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Periodical
The Journal of supercritical fluids.
ISSN: 18728162 08968446 Year: 1988 Publisher: [Amsterdam] : Elsevier Science


Book
Hyphenated techniques in supercritical fluid chromatography and extraction
Author:
ISBN: 9780444887948 0444887946 9780080858616 0080858619 9786611789350 1281789356 Year: 1992 Volume: 53 Publisher: Amsterdam New York Elsevier

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Abstract

This is the first book to focus on the latest developments in hyphenated techniques using supercritical fluids. The advantages of SFC in hyphenation with various detection modes, such as FTIR, MS, MPD and ICP and others are clearly featured throughout the book. Special attention is paid to coupling of SFE with GC or SFC. In this edited volume, chapters are written by leading experts in the field. The book will be of interest to professionals in academia, as well as to those researchers working in an industrial environment, such as analytical instrumentation, pharmaceuticals, agricult


Book
Practical application of supercritical fluid chromatography for pharmaceutical research and development
Authors: ---
ISBN: 0323884873 9780323884884 0323884881 9780323884877 9780323884877 Year: 2022 Publisher: [Place of publication not identified] : Academic Press,

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Abstract

Practical Application of Supercritical Fluid Chromatography for Pharmaceutical Research and Development provides a valuable "go-to" reference for many difficult-to-solve challenges using pertinent chromatographic theory, first-hand case studies, and examples provided from academic and industry experts. This text also enables professors teaching an analytical instrumental course to introduce and instruct students about one of the most sustainable and powerful separation methods currently available. While the text has broad applicability across industrial sectors, it focuses primarily on application in the pharmaceutical industry. The book is designed to allow readers to align current HPLC/UHPLC capabilities with SFC as an orthogonal tool for project specific methods in the pharmaceutical industry. It highlights where SFC falls on the spectrum of useful chromatographic tools for routine and challenging separative methods. Experienced HPLC users who are interested in developing knowledge in orthogonal separation techniques, as well as newcomers to the field of separation science, will find this text particularly useful. Chapters address where SFC may fit the analytical needs of the pharmaceutical industry and alert the readers as to where the technique will not fit. Readers will gain an understanding of how and where SFC may be applied and adapted more routinely across the pharmaceutical industry as a 'green' way of undertaking separation opportunities and challenges. Areas within the pharmaceutical industry include early drug discovery, process chemistry, and late stage development and manufacturing.

Supercritical fluid : methods and protocols
Authors: ---
ISBN: 0896035719 9786610820269 1280820268 1592590306 1617370797 Year: 2000 Publisher: Clifton, NJ : Humana Press,

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Because of their unique properties and relatively low environmental impact, supercritical fluids have proven highly useful in the extraction and separation of organic compounds, in particle production, as reaction media, and for the destruction of toxic waste. In Supercritical Fluid Methods and Protocols, experienced practitioners present detailed accounts of a wide variety of techniques using supercritical fluids. These range from the supercritical fluid extraction methods for numerous compounds to the ninhydrin staining of fingerprints on checks and banknotes, and from the detection of impurities in pharmaceuticals to a wide variety of applications throughout environmental and food science, and across analytical, clinical, and medicinal chemistry. Detailed step-by-step instructions enable users to apply these essential techniques successfully the first time, and include modifications that permit their effective adaptation to novel experimental or process conditions. For each application, additional discussions provide needed background information, lists of materials and apparatus, and advice about common pitfalls and how to avoid them. Versatile and comprehensive, Supercritical Methods and Protocols offers both novice and experienced investigators and laboratory analysts powerful tools that will enable successful biological and bioprocess analyses and optimizations today.

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