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Almost 30 years have gone by since the postulation that GISTs derive from mesenchymal stem elements, and only 15 years have gone by since the definitive detection of origin of GISTs. Research in the last decade was more focused upon the justification of imatinib mezylate therapy in GISTs and clarification why a secondary resistance that occurred during the kinase inhibitors therapy. The era of therapy for GISTs, targeting the primary activating mutations in the KIT proto-oncogene; is being proclaimed as bringing the message of special importance to the pathologist role in multidisciplinary team that are responsible for treating patients with locally advanced or metastatic GIST. This is the first conclusive message forthcoming from this book. On the other hand, the book provides summarised and case-based knowledge on current management of gastrointestinal and extragastrointestinal stromal tumours. We hope that this book may be considered as a worthwhile timely addition to clinical science dissemination, medical education, further basic and clinical research.

Gastrointestinal stromal tumors. --- GISTs (Gastrointestinal stromal tumors) --- Stromal tumors, Gastrointestinal --- Gastrointestinal system --- Tumors --- Oncology

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This book aims to provide a complete overview of the diagnosis and treatment of gastrointestinal stromal tumors (GISTs). It has been conceived to be both a detailed guide for clinical practice and an updated reference for all those involved in the evaluation of GISTs imaging. The publication provides comprehensive descriptions of the full range of common imaging and nonimaging techniques used in the diagnosis and followup of GISTs. Techniques reviewed include: · Conventional radiography · Endoscopy and endoscopic ultrasound · Conventional, color-Doppler and contrast-enhanced ultrasound · Computed tomography · Magnetic resonance imaging, and · Contrast-enhanced PET/CT imaging Both medical and surgical treatment strategies are also fully reviewed. Finally, the book concludes with a chapter that aims to stimulate widespread interest in the formation of new GISTs Units. Written by experts in the field, the book is enriched throughout by numerous black-and-white and color images, making it an invaluable source of information as well as an indispensable guide to interpreting images for radiologists, gastroenterologists, pathologists, oncologists and surgeons.  .

Digestive organs -- Cancer. --- Digestive organs. --- Gastrointestinal Neoplasms. --- Gastrointestinal Neoplasms --- Digestive System Neoplasms --- Gastrointestinal Diseases --- Neoplasms by Site --- Digestive System Diseases --- Diseases --- Neoplasms --- Gastrointestinal Stromal Tumors --- Medicine --- Health & Biological Sciences --- Radiology, MRI, Ultrasonography & Medical Physics --- Gastrointestinal stromal tumors. --- GISTs (Gastrointestinal stromal tumors) --- Stromal tumors, Gastrointestinal --- Medicine. --- Radiology. --- Nuclear medicine. --- Oncology. --- Pathology. --- Computers. --- Medicine & Public Health. --- Imaging / Radiology. --- Diagnostic Radiology. --- Nuclear Medicine. --- Information Systems and Communication Service. --- Gastrointestinal system --- Tumors --- Radiology, Medical. --- Oncology  . --- Information systems. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Atomic medicine --- Radioisotopes in medicine --- Medical radiology --- Radioactive tracers --- Radioactivity --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Physiological effect --- Automatic computers --- Automatic data processors --- Computer hardware --- Computing machines (Computers) --- Electronic brains --- Electronic calculating-machines --- Electronic computers --- Hardware, Computer --- Computer systems --- Cybernetics --- Machine theory --- Calculators --- Cyberspace --- Radiological physics --- Physics --- Radiation