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To this day, Status Epilepticus is a condition not fully understood. The pathological mechanisms are vague and the treatments available are still for some of them empirical. Status Epilepticus only affects a small part of the population, but it is nevertheless a condition that, if not treated in time, can be fatal. There is much paper on the subject, but even if the authors agree on some points, there are divergent opinions and predilection medications change from one study to another. The aim of this work is to unify existing data based on expert opinions, guidelines and multi-analyzes, and using the rest of the literature to resolve divergences and fill in the data gaps. L'EME est une maladie encore assez mal comprise. Ces mécanismes pathologiques sont vagues et les traitements disponibles sont encore pour certains empiriques. Elle ne touche qu'une petite partie de la population, mais ça n'en fait pas moins une condition qui, si elle n'est pas traitée à temps, peut être fatale. Ils existent de nombreux travaux concernant l'EME, mais même si les auteurs s'accordent sur certains points, bien souvent, les avis divergent et les médications de prédilections changent d'une étude à l'autre. Ce travail a pour but d'unifier les données existantes en se basant principalement sur les opinions d'experts, des guidelines et des multi analyses, et en utilisant le reste de la littérature pour réglé les divergences et comblé le manque de données.

Status Epilepticus --- Algorithms

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"Interest in status epilepticus--the most extreme form of epilepsy, involving continuous seizures--has surged in the last 20 years. Since 1979 there have been over 4,000 publications on the subject, including more than 1,700 in the last five years. No other text provides such a comprehensive review of the recent advances in the field of status epilepticus. The book focuses on the two areas in which progress has been most rapid: basic mechanisms and treatment. There is now a greater understanding of the mechanisms and complications of status epilepticus at the molecular level, which should eventually lead to improved therapy, and treatment strategies today have a greater sense of urgency because of the realization that neuronal apoptosis and necrosis can be triggered very quickly. After an overview of history, classification, and epidemiology, the contributors consider clinical phenomenology, biological markers, pathophysiology, brain damage, epileptogenesis, therapeutic principles, pharmacology, and therapeutic management. Their contributions are equally divided between studies of basic mechanisms in animal models and clinical studies, so that the reader can turn easily from the reductionist experiment that isolates a small component of status to the complex clinical situation in which these principles can translate into therapeutic action. The goal is to provide a scientific rationale for clinical decisions while developing therapeutic attitudes that are firmly grounded in pathophysiology"--MIT CogNet.

Epilepsy --- Convulsions --- Status Epilepticus --- Brain Diseases --- Central Nervous System Diseases --- Nervous System Diseases --- Diseases --- Neurology --- Medicine --- Health & Biological Sciences --- Treatment --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- CNS Diseases --- Central Nervous System Disorders --- CNS Disease --- Brain Disorders --- CNS Disorders, Intracranial --- Central Nervous System Disorders, Intracranial --- Central Nervous System Intracranial Disorders --- Encephalon Diseases --- Encephalopathy --- Intracranial CNS Disorders --- Intracranial Central Nervous System Disorders --- Brain Disease --- Brain Disorder --- CNS Disorder, Intracranial --- Encephalon Disease --- Encephalopathies --- Intracranial CNS Disorder --- Epilepsy, Cryptogenic --- Seizures, Epileptic --- Single Seizure --- Aura --- Awakening Epilepsy --- Epileptic Seizures --- Seizure Disorder --- Auras --- Cryptogenic Epilepsies --- Cryptogenic Epilepsy --- Epilepsies --- Epilepsies, Cryptogenic --- Epilepsy, Awakening --- Epileptic Seizure --- Seizure Disorders --- Seizure, Epileptic --- Seizure, Single --- Seizures, Single --- Single Seizures --- Grand Mal Status Epilepticus --- Status Epilepticus, Complex Partial --- Status Epilepticus, Electrographic --- Status Epilepticus, Generalized --- Status Epilepticus, Generalized Convulsive --- Status Epilepticus, Grand Mal --- Status Epilepticus, Non-Convulsive --- Status Epilepticus, Simple Partial --- Status Epilepticus, Subclinical --- Absence Status --- Complex Partial Status Epilepticus --- Generalized Convulsive Status Epilepticus --- Non-Convulsive Status Epilepticus --- Petit Mal Status --- Simple Partial Status Epilepticus --- Electrographic Status Epilepticus --- Generalized Status Epilepticus --- Non Convulsive Status Epilepticus --- Status Epilepticus, Non Convulsive --- Status, Absence --- Status, Petit Mal --- Subclinical Status Epilepticus --- Convulsive disorders --- Convulsive seizures --- Seizures, Convulsive --- Seizures --- Nervous system --- Spasms --- Brain --- Developmental disabilities --- Epilepsy. --- Convulsions. --- Treatment. --- NEUROSCIENCE/General

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Medicine --- Neurology & clinical neurophysiology --- Status Epilepticus --- Epilepsy --- Seizures --- Anticonvulsants --- Autoimmune epilepsy --- Temporal Lobe Epilepsy --- Epileptogenesis

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Status Epilepticus --- Epilepsy --- Seizures --- Anticonvulsants --- Autoimmune epilepsy --- Temporal Lobe Epilepsy --- Epileptogenesis

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Clinical neurologic examination remains the cornerstone of modern neurology. However, it provides rather limited information when facing critically ill neurologic patients, especially those with altered mental status. The underlying mechanisms might include nonconvulsive seizures, cerebral hemodynamic failure, brain edema, delayed cerebral ischemia (DCI), intracranial hypertension, etc.. Most of them are invisible but detectable. Integration of various monitoring and evaluation methods have been applied in neurologic intensive care unit (NICU), to interpret electric, biochemical and physiological changes of the brain into objective data, which help physicians select patients suitable for specific interference, recognize the treatable disorders, assess the response to treatment and prevent secondary injuries. Because some progress has been made lately, it is important for clinicians in NICU to update the concepts and knowledge of multimodality monitoring and evaluation, as well as to explore what is still needed in modern NICU. In this Research Topic, we collect articles regarding monitoring methods/techniques and their application in common neurocritical diseases.

Medicine --- Neurology & clinical neurophysiology --- acute ischemic stroke --- anoxic brain injury --- encephalitis --- multi-modality monitoring --- outcome --- prognostication --- status epilepticus --- acute ischemic stroke --- anoxic brain injury --- encephalitis --- multi-modality monitoring --- outcome --- prognostication --- status epilepticus