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This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: historical background; medical significance in humans and animals; genetic variation; virulence factors; metabolism and physiology; physiological proteomics; cell wall assembly and physiology; transition metal ion homeostasis; molecular strategies of antibiotic resistance; genetic regulation; and immune response. Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.

Staphylococcus aureus.

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Staphylococcus aureus is resident in skin and nasal membranes with a formidable pathogenic potential to cause a variety of community and hospital acquired infections. This authoritative survey covers the impact of genome sequences into our understanding of MRSA and MSSA pathogenesis. World specialists from America, Germany, Japan, Sweden and the UK contribute knowledge and experience which will be welcome to researchers, practitioners and postgraduate students of immunology, microbiology, bacteriology and pharmacology worldwide.An authoritative survey that covers the impact of

Staphylococcus aureus. --- Staphylococcus aureus infections. --- Staphylococcus aureus infections --- Staphylococcus aureus --- Epidemiology. --- Pathogenesis. --- Genetic aspects.

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In the twenty first century, the bacterium Staphylococcus aureus continues to be a global threat to human and animal health. There is currently no vaccine for preventing S. aureus infections and the bacterium has developed resistance to many, if not most, antibiotics, hence the therapeutic options are rapidly disappearing. The genetic and physiological flexibility that allows this commensal bacterium to become a powerful pathogen and elucidating the myriad of mechanisms it employs to avoid the host and/or antimicrobials are important areas of research.This book brings together respected S. aureus experts from around the world to provide a timely overview of staphylococcal research. Topics covered include: medical significance; genetic variation; virulence factors; metabolism; proteomics; cell wall assembly; antibiotic resistance; genetic regulation; and immune response.Essential reading for scientists working with staphylococci. This text is an excellent introduction for entry level scientists, as well as those seeking a deeper understanding of this critically important bacterial pathogen.

Staphylococcus aureus. --- Staphylocoque doré.

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The staphylococcus aureus, more specificially the j/IRSA (Methicillin Resistant Staphylococcus Aureus) is the pathogenic bacterium wich is found the most in hospitals. Two different clones can be found : the CA - MRSA (Community Acquired MRSA) and the HA - MRSA (Hospital Acquired MRSA). The HA - MRSA has its origin in hospitals and is therefore detected when the patient gets it within 48 to 72 hours after his admission to the hospital. To the contrary the CA - MRSA has infected the patient before his admission to the hospital.
The staphylococcus aureus started to become resistant mainly because of an improper use of antibiotics. A resistance to penicillin and methicillin (MRSA) was first discovered. ln this case the only antibiotics which still works on this germ is the vaneomyein. Unfortunately some clones developed lately a resistance to that substance as well. People mostly affected by the staphylococcus aureus are among others weakened people, diabetic patients, old people, people who have a catheter or a prosthesis.
Of course the staphylococcus aureus will result in diseases such as but not lirnited to skin and flabby tissues infections, endocarditis and blood poisoning (septicaemia). The mortality rate will also increase.
ln order to avoid the above problems the hospital will establish several prevention measures such as for example hand hygiene, precautionary measusres and detection of infected patients. These patients will be isolated in separate rooms and the hospital personnel who takes care of them will take care of them will take precautionary measures as well as have a good hand hygiene Le staphylocoque doré, et plus particulièrement le MRSA (Methicillin Resistant Staphylococcus Aureus) est une des bactéries pathogènes les plus présentes à l'hôpital. On y trouvera 2 souches différentes, le CA et le HA - MRSA (Cornrnunity - Acquired et Hospital- Acquired MRSA). Le HA - MRSA trouve son origine dans l'hôpital et est d'ailleurs défini quand le patient l'acquiert dans un délai de 48 à 72 heures après son admission. Tandis que le CA - MRSA a déjà été acquis en dehors de l'hôpital.
Le staphylocoque doré a commencé à développer des résistances surtout à cause de l'usage inaproprié des antibiotiques. On a d'abord trouvé une résitance à la pénicilline et à la méthicilline (MRSA). Dans ce dernier cas, un des seuls antibiotiques ayant encore une action sm ce germe est la vancomycine. Mais hélas depuis quelques armées, certaines souches ont aussi acquis cette résistance. Les personnes les plus touchées sont des personnes affaiblies, des diabétiques, des personnes âgées, portant des cathéters, des prothèses, ...
Bien entendu, le staphylocoque doré va avoir comme conséquences des maladies telles que des infections de la peau et des tissus mous, des endocardites, des septicémies, ... Il va aussi augmenter le taux de mortalité.
Pour éviter toutes ces conséquences, l'hôpital mettra en place toute une série d'actions de prévention comme l'hygiène des mains, la mise en place de barrières de précaution, la détection de patients colonisés, ... On isolera ces derniers dans des chambres à part et le personnel hospitalier s'en occupant mettra en place des barrières de précaution et effectuera une bonne prévention de l'hygiène des mains.

Staphylococcus aureus --- Methicillin-Resistant Staphylococcus aureus --- Hospitals --- Patients

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Staphylococcus aureus infections. --- Staphylococcal infections