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This book points to some new areas for investigation on squamous cell carcinoma (SCC). Firstly, the features and management of some specific SCC is discussed to give the readers the general principles in dealing with these uncommon and sophisticated conditions. Some new concepts in adjuvant therapy including neoadjuvant therapy and gold nanoparticle-based photo dynamic therapy are introduced. Secondly, a detailed discussion of molecular aspects of tumor invasion and progression in SCC is provided with the emphasis on the roles of some important factors. The role of tumor microenvironment in head and neck SCC is specifically discussed. Thirdly, the roles of cancer stem cells (CSC) in cancer therapy of SCC are described. Molecular mechanisms involving therapeutic resistance and new therapeutic strategies targeting CSC are discussed in detail. Finally, other aspects concerning SCC are included, which involve the assessment, genetic manipulation and its possible clinical implications for the treatment of SCC.

Squamous cell carcinoma. --- SCC (Oncology) --- Squamous cell cancer --- Cancer --- Oncology

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Cellule d'épithéliome spinocellulaire --- Epithelioomcel spinocellulare --- Epithéliome spinocellulaire [Cellule d' ] --- SCC (Oncology) --- Squamous cell cancer --- Squamous cell carcinoma --- Anus --- Cancer

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46.80 clinical veterinary medicine. --- BCG vaccine. --- BCG vaccines --- Cattle --- Cattle. --- Eyes. --- Horses --- Horses. --- Immunotherapy. --- Sarcoids. --- Squamous-cell cancer. --- Veterinary immunology. --- Therapeutic use. --- Diseases --- Chemotherapy. --- Diseases --- Chemotherapy.

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This open access book discusses the most current issues in head and neck cancer with a focus on current trends such as biomarkers, precision medicine and immunotherapy. New approaches in the diagnosis such as liquid biopsies and imaging biomarkers to predict radiotherapy toxicity as well as approaches in the surgical management of head and neck cancers are discussed. The book discusses medical and surgical approaches in both primary, recurrent and metastatic disease and also covers approaches for rare head neck cancers. Readers will learn about the latest drug developments and epidemiological aspects in cancers ranging from head and neck squamous cell cancer to nasopharynx cancer. Edited by a team of world leaders in head and neck cancer, this volume serves as an easy reference to the head and neck oncology practitioner and provides a contemporary overview for specialists the field. The chapters are based on the latest data presented at the 7th Trends in Head and Neck Oncology Conference and reflect the most up-to-date information in the field.

Oncology  . --- Radiotherapy. --- Surgical oncology. --- Oncology. --- Surgical Oncology. --- Cancer --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Tumors --- Excision --- Treatment --- Radiological services --- Càncer de coll --- Càncer de cap --- Cirurgia oncològica --- Cirurgia del càncer --- Extirpació del càncer --- Oncologia quirúrgica --- Cirurgia --- Càncer --- Oncology --- Radiotherapy --- Surgical Oncology --- Internal Medicine --- Radiology --- Surgery --- Nasopharynx cancer --- Head and Neck Squamous Cell Cancer --- non-oropharyngeal head and neck cancer --- predictive biomarkers --- liquid biopsies --- induction chemotherapy --- immunotherapy --- precision medicine --- HNSCC --- Open Access

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Squamous cell carcinoma of the esophagus has a lower incidence than other gastrointestinal tract cancer; however, there are many difficult issued related to the choice of appropriate therapy for these patients. In recent years, the use of multimodal treatment has greatly improved the prognosis of patients affected by this disease but several aspects of the oncological and surgical management are still controversial. This book aims to give a homogeneous approach to esophageal cancer treatment, based on the author’s lifetime experience in conjunction with exhaustive review of recent literature. In each chapter surgeons and oncologists will find appropriate tools for correct management of the diagnosis and therapy of this difficult disease. The book analyzes all the aspects of staging and treatment, such as modern diagnostic and staging techniques (MRI or PET-CT), endoscopic treatment of early cancer, new minimally invasive and open surgical techniques, and combined treatment. In addition, there are chapters dedicated to the postoperative course of these patients, as well as their quality of life, with indications for the correct follow-up and treatment of relapses.

Cancer -- Radiotherapy -- Examinations, questions, etc. --- Neoplasms -- radiotherapy -- Examination Questions. --- Esophagus --- Squamous cell carcinoma --- Gastrointestinal system --- Pharyngeal Neoplasms --- Carcinoma --- Gastrointestinal Neoplasms --- Head and Neck Neoplasms --- Esophageal Diseases --- Neoplasms, Squamous Cell --- Digestive System Neoplasms --- Neoplasms, Glandular and Epithelial --- Otorhinolaryngologic Neoplasms --- Gastrointestinal Diseases --- Pharyngeal Diseases --- Neoplasms by Site --- Digestive System Diseases --- Neoplasms by Histologic Type --- Stomatognathic Diseases --- Otorhinolaryngologic Diseases --- Neoplasms --- Diseases --- Hypopharyngeal Neoplasms --- Carcinoma, Squamous Cell --- Esophageal Neoplasms --- Medicine --- Surgery & Anesthesiology --- Health & Biological Sciences --- Oncology --- Surgery - General and By Type --- Treatment --- Cancer --- Hypopharynx --- Squamous cell carcinoma. --- Cancer. --- SCC (Oncology) --- Squamous cell cancer --- Medicine. --- Radiotherapy. --- Gastroenterology. --- Oncology. --- Surgery. --- Medicine & Public Health. --- Surgery, Primitive --- Tumors --- Internal medicine --- Digestive organs --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Radiological services --- Oncology  . --- Gastroenterology .