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Book
Life span : evolutionary, ecological, and demographic perspectives
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ISBN: 0878341110 9780878341115 Year: 2003 Volume: 29 Publisher: New York, N.Y. Population Council


Book
Social bioarchaeology
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ISBN: 9781444337679 9781405191876 1405191872 144433767X Year: 2011 Volume: 14 Publisher: Chichester Wiley-Blackwell

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"Social bioarchaeology introduces the exciting and growing biosocial approach in archaeology that challenges the traditional methods of analyzing and interpreting human skeletal remains. Agarwal, Glencross, and the experts assembled in this volume outline the essential components of this research, focusing on the dynamic interactions between humans and their larger social, cultural, and physical environments, and how these analyses increase our understanding of human adaptation. The authors draw upon studies from the Americas, Europe, and the Middle East examining the central themes, theoretical issues, and methodological innovations in the field. Each chapter offers significant new research that integrates elements from biological, behavioural, ecological and social research. This new volume will be a valuable resource for archaeologists, biological anthropologists, paleopathologists, and all researchers with an interest in understanding our social and biological adaptations in a constantly changing global environment"--Provided by publisher.


Book
Life-span extension : single-cell organisms to man
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ISBN: 1603275061 9786612333392 1282333399 160327507X Year: 2009 Publisher: Totowa, N.J. : London : Humana ; Springer [distributor],

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In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process. Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice. Novel, emerging technologies and the increasingly wide variety of systems that are now used to study aging and the mechanisms of aging provide enormous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.

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