Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The book focuses on a global problem challenging the health systems. Trypanosoma cruzi infections are transmitted by cone-nosed triatomine bugs, by blood transfusion and congenitally from mothers to their offspring. The American Trypanosomiasis affects 20 million people; among them a significant parcel (< 1/3) will develop Chagas disease in the heart and digestive tract, where the immune system effector cells destroy target host cells. Genotype modifications resulting from transfer of minicircle sequence kDNA from the parasite into the host ́s genome may explain the autoimmune pathogenesis.

Chagas' disease. --- American trypanosomiasis --- Barbiero fever --- Cruz-Chagas disease --- South American trypanosomiasis --- Trypanosomiasis

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Even 110 years after its discovery, Chagas disease is still an important public health problem, especially in Latin America where it is endemic. The limited effect of current treatments in the chronic phase of the disease, as well as the lack of information about disease progression, are crucial challenges that justify the intense research on this illness. The interaction between the etiological agent Trypanosoma cruzi and its invertebrate and vertebrate hosts involves the regulation of the parasite virulence and host immune responses. T. cruzi presents mechanisms to evade host defenses, including resistance to oxidative species and vesicles secretion, among many others. In this context, a better understanding of the biochemical and molecular features of the parasite's success inside its hosts could contribute to the development of novel anti-T. cruzi strategies such as prototypes of drugs and vaccines. This book discusses Chagas disease and its etiological agent, including information on relevant clinical aspects such as diagnosis, treatment, biomarkers, and so on. It also presents information about cellular, molecular, and biochemical characteristics of the parasite-host interactions.

Chagas' disease. --- American trypanosomiasis --- Barbiero fever --- Cruz-Chagas disease --- South American trypanosomiasis --- Trypanosomiasis

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Este admirável volume reuniu especialistas de diversos campos do conhecimento para comentar a importância de 15 artigos clássicos associados à descoberta científica de Carlos Chagas, que completou cem anos em 2009. A obra indica novas diretrizes e os desafios que ainda cercam a doença na atualidade. Organizado por pesquisadoras do Instituto Oswaldo Cruz (IOC/Fiocruz) e da Casa de Oswaldo Cruz (COC/Fiocruz), pela coordenadora de eventos da Fiocruz e por um ex-vice-presidente de pesquisa da instituição, que juntos formaram uma rede para definir quais seriam os principais artigos clássicos que demarcaram o avanço das pesquisas sobre doença de Chagas, o livro contextualiza-os em relação ao centenário e “…assim surge…, coletivo, histórico e atual”, nas palavras de uma das organizadoras.

Chagas' disease --- Diseases --- History. --- Transmission. --- Causes and theories of causation. --- Aetiology --- Etiology --- Pathology --- American trypanosomiasis --- Barbiero fever --- Cruz-Chagas disease --- South American trypanosomiasis --- Trypanosomiasis --- History of medicine

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This title critically reviews old and new literature, help to create greater awareness of the disease in the US and helps in the evaluation of certain epidemiological and public health issues. During the first half of the 20th century, Chagas disease was assumed to be absent from the U.S. and considered an exotic disease, until the first two indigenous cases were discovered, almost simultaneously, in Texas, 1955. Since that time four indigenous cases have been documented in several places in the country. Although the disease is still considered uncommon in the US, this disease is not

Chagas' disease -- Epidemiology. --- Chagas Disease -- epidemiology. --- Chagas' disease --- Public Health --- Medicine --- Health & Biological Sciences --- Communicable Diseases --- Infectious Diseases --- Epidemiology --- Emerging infectious diseases. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- American trypanosomiasis --- Barbiero fever --- Cruz-Chagas disease --- South American trypanosomiasis --- Trypanosomiasis

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book aims to present updated knowledge on various aspects of the natural history, biology, and impact of triatomines to all interested readers. Each chapter will be written by authorities in the respective field, covering topics such as behavior, neurophysiology, immunology, ecology, and evolution. The contents will consider scientific, as well as innovative perspectives, on the problems related to the role of triatomine bugs as parasite vectors affecting millions in the Latin American region.

Conenoses as carriers of disease. --- Chagas' disease. --- American trypanosomiasis --- Barbiero fever --- Cruz-Chagas disease --- South American trypanosomiasis --- Trypanosomiasis --- Insects as carriers of disease --- Invertebrates. --- Parasitology. --- Veterinary microbiology. --- Invertebrate Zoology. --- Veterinary Microbiology. --- Parasitologia --- Microbiologia veterinària --- Malaltia de Chagas --- Agricultural microbiology --- Medical microbiology --- Communicable diseases in animals --- Biology --- Invertebrata --- Animals