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For nearly 30 years, Dr. Meir Kryger's must-have guide to sleep medicine has been the gold standard in this fast-changing field. This essential, full-color reference includes more than 20 unique sections and over 170 chapters covering every aspect of sleep disorders, giving you the authoritative guidance you need to offer your patients the best possible care. For this updated 6th edition, extensive additional online material enhances the value of Principles and Practice of Sleep Medicine to your practice.

Sleep disorders. --- Sleep --- Physiological aspects. --- Dyssomnias --- Adjustment Sleep Disorder --- Environmental Sleep Disorder --- Limit-Setting Sleep Disorder --- Nocturnal Eating-Drinking Syndrome --- Sleep Disorder, Adjustment --- Sleep Disorder, Environmental --- Sleep Disorder, Limit-Setting --- Sleep Disorders, Extrinsic --- Adjustment Sleep Disorders --- Dyssomnia --- Eating-Drinking Syndrome, Nocturnal --- Eating-Drinking Syndromes, Nocturnal --- Environmental Sleep Disorders --- Extrinsic Sleep Disorder --- Extrinsic Sleep Disorders --- Limit Setting Sleep Disorder --- Limit-Setting Sleep Disorders --- Nocturnal Eating Drinking Syndrome --- Nocturnal Eating-Drinking Syndromes --- Sleep Disorder, Extrinsic --- Sleep Disorder, Limit Setting --- Sleep Disorders, Adjustment --- Sleep Disorders, Environmental --- Sleep Disorders, Limit-Setting --- Syndrome, Nocturnal Eating-Drinking --- Syndromes, Nocturnal Eating-Drinking --- Disorders of sleep --- Nervous system --- Psychology, Pathological --- Diseases --- Sleep Wake Disorders --- Long Sleeper Syndrome --- Short Sleep Phenotype --- Short Sleeper Syndrome --- Sleep-Related Neurogenic Tachypnea --- Subwakefullness Syndrome --- Sleep Disorders --- Disorder, Sleep --- Disorder, Sleep Wake --- Disorders, Sleep --- Disorders, Sleep Wake --- Long Sleeper Syndromes --- Neurogenic Tachypnea, Sleep-Related --- Neurogenic Tachypneas, Sleep-Related --- Phenotype, Short Sleep --- Phenotypes, Short Sleep --- Short Sleep Phenotypes --- Short Sleeper Syndromes --- Sleep Disorder --- Sleep Phenotypes, Short --- Sleep Related Neurogenic Tachypnea --- Sleep Wake Disorder --- Sleep-Related Neurogenic Tachypneas --- Sleeper Syndrome, Long --- Sleeper Syndrome, Short --- Sleeper Syndromes, Long --- Sleeper Syndromes, Short --- Subwakefullness Syndromes --- Syndrome, Long Sleeper --- Syndrome, Short Sleeper --- Syndrome, Subwakefullness --- Syndromes, Long Sleeper --- Syndromes, Short Sleeper --- Syndromes, Subwakefullness --- Tachypnea, Sleep-Related Neurogenic --- Tachypneas, Sleep-Related Neurogenic --- Wake Disorder, Sleep --- Wake Disorders, Sleep --- Sleep Hygiene --- physiology

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Sleep Apnea, Obstructive --- Sleep Apnea Syndromes --- Sleep Disorders, Intrinsic --- Apnea --- Dyssomnias --- Respiration Disorders --- Respiratory Tract Diseases --- Sleep Disorders --- Nervous System Diseases --- Diseases --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Neurology --- Long Sleeper Syndrome --- Short Sleep Phenotype --- Short Sleeper Syndrome --- Sleep-Related Neurogenic Tachypnea --- Subwakefullness Syndrome --- Disorder, Sleep --- Disorder, Sleep Wake --- Disorders, Sleep --- Disorders, Sleep Wake --- Long Sleeper Syndromes --- Neurogenic Tachypnea, Sleep-Related --- Neurogenic Tachypneas, Sleep-Related --- Phenotype, Short Sleep --- Phenotypes, Short Sleep --- Short Sleep Phenotypes --- Short Sleeper Syndromes --- Sleep Disorder --- Sleep Phenotypes, Short --- Sleep Related Neurogenic Tachypnea --- Sleep Wake Disorder --- Sleep-Related Neurogenic Tachypneas --- Sleeper Syndrome, Long --- Sleeper Syndrome, Short --- Sleeper Syndromes, Long --- Sleeper Syndromes, Short --- Subwakefullness Syndromes --- Syndrome, Long Sleeper --- Syndrome, Short Sleeper --- Syndrome, Subwakefullness --- Syndromes, Long Sleeper --- Syndromes, Short Sleeper --- Syndromes, Subwakefullness --- Tachypnea, Sleep-Related Neurogenic --- Tachypneas, Sleep-Related Neurogenic --- Wake Disorder, Sleep --- Wake Disorders, Sleep --- Sleep Hygiene --- Disease, Respiratory Tract --- Diseases, Respiratory Tract --- Respiratory Tract Disease --- Tract Disease, Respiratory --- Tract Diseases, Respiratory --- Disorder, Respiration --- Disorders, Respiration --- Respiration Disorder --- Adjustment Sleep Disorder --- Environmental Sleep Disorder --- Limit-Setting Sleep Disorder --- Nocturnal Eating-Drinking Syndrome --- Sleep Disorder, Adjustment --- Sleep Disorder, Environmental --- Sleep Disorder, Limit-Setting --- Sleep Disorders, Extrinsic --- Adjustment Sleep Disorders --- Dyssomnia --- Eating-Drinking Syndrome, Nocturnal --- Eating-Drinking Syndromes, Nocturnal --- Environmental Sleep Disorders --- Extrinsic Sleep Disorder --- Extrinsic Sleep Disorders --- Limit Setting Sleep Disorder --- Limit-Setting Sleep Disorders --- Nocturnal Eating Drinking Syndrome --- Nocturnal Eating-Drinking Syndromes --- Sleep Disorder, Extrinsic --- Sleep Disorder, Limit Setting --- Sleep Disorders, Adjustment --- Sleep Disorders, Environmental --- Sleep Disorders, Limit-Setting --- Syndrome, Nocturnal Eating-Drinking --- Syndromes, Nocturnal Eating-Drinking --- Apneas --- Respiration --- Hypersomnia, Post-Traumatic --- Hypersomnia, Posttraumatic --- Sleep State Misperception --- Intrinsic Sleep Disorders --- Hypersomnia, Post Traumatic --- Hypersomnias, Post-Traumatic --- Hypersomnias, Posttraumatic --- Intrinsic Sleep Disorder --- Post-Traumatic Hypersomnia --- Post-Traumatic Hypersomnias --- Posttraumatic Hypersomnia --- Posttraumatic Hypersomnias --- Sleep Disorder, Intrinsic --- Sleep State Misperceptions --- Mixed Central and Obstructive Sleep Apnea --- Sleep Apnea, Mixed --- Sleep Apnea, Mixed Central and Obstructive --- Sleep Hypopnea --- Apnea, Sleep --- Hypersomnia with Periodic Respiration --- Sleep-Disordered Breathing --- Apnea Syndrome, Sleep --- Apnea Syndromes, Sleep --- Apneas, Sleep --- Breathing, Sleep-Disordered --- Hypopnea, Sleep --- Hypopneas, Sleep --- Mixed Sleep Apnea --- Mixed Sleep Apneas --- Sleep Apnea --- Sleep Apnea Syndrome --- Sleep Apneas --- Sleep Apneas, Mixed --- Sleep Disordered Breathing --- Sleep Hypopneas --- Apnea, Obstructive Sleep --- OSAHS --- Obstructive Sleep Apnea Syndrome --- Sleep Apnea Hypopnea Syndrome --- Sleep Apnea Syndrome, Obstructive --- Syndrome, Obstructive Sleep Apnea --- Syndrome, Sleep Apnea, Obstructive --- Syndrome, Upper Airway Resistance, Sleep Apnea --- Obstructive Sleep Apnea --- Upper Airway Resistance Sleep Apnea Syndrome --- Apneas, Obstructive Sleep --- Obstructive Sleep Apneas --- Sleep Apneas, Obstructive --- Respiratory Diseases --- Respiratory System Diseases --- Disease, Respiratory System --- Respiratory System Disease

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Fatigue --- Automotive medicine --- Dyssomnias --- Sleep --- Technology, Industry, and Agriculture --- Signs and Symptoms --- Sleep Disorders --- Psychophysiology --- Nervous System Physiological Processes --- Pathological Conditions, Signs and Symptoms --- Neurologic Manifestations --- Technology, Industry, Agriculture --- Psychological Phenomena and Processes --- Mental Disorders --- Nervous System Diseases --- Diseases --- Nervous System Physiological Phenomena --- Psychiatry and Psychology --- Musculoskeletal and Neural Physiological Phenomena --- Phenomena and Processes --- Sleep Deprivation --- Transportation --- Medicine --- Health & Biological Sciences --- Transportation Medicine & Physiology --- Psychologic Processes --- Psychologic Processes and Principles --- Psychological Processes --- Phenomena, Psychological --- Processes, Psychologic --- Processes, Psychological --- Psychological Phenomenas --- Psychological Processe --- Focal Neurologic Deficits --- Manifestations, Neurologic --- Manifestations, Neurological --- Neurologic Dysfunction --- Neurologic Findings --- Neurologic Manifestation --- Neurologic Signs --- Neurologic Symptoms --- Neurological Manifestations --- Neurologic Deficits --- Neurologic Signs and Symptoms --- Deficit, Focal Neurologic --- Deficit, Neurologic --- Deficits, Focal Neurologic --- Deficits, Neurologic --- Dysfunction, Neurologic --- Dysfunctions, Neurologic --- Finding, Neurologic --- Findings, Neurologic --- Focal Neurologic Deficit --- Manifestation, Neurologic --- Manifestation, Neurological --- Neurologic Deficit --- Neurologic Deficit, Focal --- Neurologic Deficits, Focal --- Neurologic Dysfunctions --- Neurologic Finding --- Neurologic Sign --- Neurologic Symptom --- Neurological Manifestation --- Sign, Neurologic --- Signs, Neurologic --- Symptom, Neurologic --- Symptoms, Neurologic --- Nervous System --- Symptoms and General Pathology --- Nervous System Physiological Concepts --- Nervous System Physiological Phenomenon --- Nervous System Physiological Process --- Physiology, Nervous System --- Nervous System Physiologic Processes --- Nervous System Physiology --- System Physiology, Nervous --- Mind-Body Relationship (Physiology) --- Physiologic Psychology --- Physiological Psychology --- Psychology, Physiologic --- Mind-Body Relations (Physiology) --- Psychology, Physiological --- Mind Body Relations (Physiology) --- Mind Body Relationship (Physiology) --- Mind-Body Relation (Physiology) --- Mind-Body Relationships (Physiology) --- Physiologic Psychologies --- Psychologies, Physiologic --- Relation, Mind-Body (Physiology) --- Relations, Mind-Body (Physiology) --- Relationship, Mind-Body (Physiology) --- Relationships, Mind-Body (Physiology) --- Psychosomatic Medicine --- Mind-Body Relations, Metaphysical --- Long Sleeper Syndrome --- Short Sleep Phenotype --- Short Sleeper Syndrome --- Sleep-Related Neurogenic Tachypnea --- Subwakefullness Syndrome --- Disorder, Sleep --- Disorder, Sleep Wake --- Disorders, Sleep --- Disorders, Sleep Wake --- Long Sleeper Syndromes --- Neurogenic Tachypnea, Sleep-Related --- Neurogenic Tachypneas, Sleep-Related --- Phenotype, Short Sleep --- Phenotypes, Short Sleep --- Short Sleep Phenotypes --- Short Sleeper Syndromes --- Sleep Disorder --- Sleep Phenotypes, Short --- Sleep Related Neurogenic Tachypnea --- Sleep Wake Disorder --- Sleep-Related Neurogenic Tachypneas --- Sleeper Syndrome, Long --- Sleeper Syndrome, Short --- Sleeper Syndromes, Long --- Sleeper Syndromes, Short --- Subwakefullness Syndromes --- Syndrome, Long Sleeper --- Syndrome, Short Sleeper --- Syndrome, Subwakefullness --- Syndromes, Long Sleeper --- Syndromes, Short Sleeper --- Syndromes, Subwakefullness --- Tachypnea, Sleep-Related Neurogenic --- Tachypneas, Sleep-Related Neurogenic --- Wake Disorder, Sleep --- Wake Disorders, Sleep --- Sleep Hygiene --- Symptoms and Signs --- Sleep Habits --- Sleeping Habit --- Sleeping Habits --- Habit, Sleep --- Habit, Sleeping --- Habits, Sleep --- Habits, Sleeping --- Sleep Habit --- Sleepiness --- Adjustment Sleep Disorder --- Environmental Sleep Disorder --- Limit-Setting Sleep Disorder --- Nocturnal Eating-Drinking Syndrome --- Sleep Disorder, Adjustment --- Sleep Disorder, Environmental --- Sleep Disorder, Limit-Setting --- Sleep Disorders, Extrinsic --- Adjustment Sleep Disorders --- Dyssomnia --- Eating-Drinking Syndrome, Nocturnal --- Eating-Drinking Syndromes, Nocturnal --- Environmental Sleep Disorders --- Extrinsic Sleep Disorder --- Extrinsic Sleep Disorders --- Limit Setting Sleep Disorder --- Limit-Setting Sleep Disorders --- Nocturnal Eating Drinking Syndrome --- Nocturnal Eating-Drinking Syndromes --- Sleep Disorder, Extrinsic --- Sleep Disorder, Limit Setting --- Sleep Disorders, Adjustment --- Sleep Disorders, Environmental --- Sleep Disorders, Limit-Setting --- Syndrome, Nocturnal Eating-Drinking --- Syndromes, Nocturnal Eating-Drinking --- Automobile driving, Medical aspects of --- Transportation medicine --- Exhaustion --- Lassitude --- Tiredness --- Weariness --- Physiology --- Symptoms --- Rest --- Commuting --- Asthenia --- Physical Exertion --- Inadequate Sleep --- Insufficient Sleep --- Insufficient Sleep Syndrome --- REM Sleep Deprivation --- Sleep Debt --- Sleep Fragmentation --- Sleep Insufficiency --- Deprivation, REM Sleep --- Deprivation, Sleep --- Fragmentation, Sleep --- Insufficiencies, Sleep --- Insufficiency, Sleep --- Insufficient Sleep Syndromes --- Sleep Deprivation, REM --- Sleep Insufficiencies --- Sleep, Inadequate --- Sleep, Insufficient --- Syndrome, Insufficient Sleep --- Musculoskeletal and Neural Physiological Concepts --- Musculoskeletal and Neural Physiological Phenomenon --- Musculoskeletal and Neural Physiology --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Neurology --- Behavior Disorders --- Diagnosis, Psychiatric --- Mental Disorders, Severe --- Psychiatric Diagnosis --- Mental Illness --- Psychiatric Diseases --- Psychiatric Disorders --- Psychiatric Illness --- Illness, Mental --- Mental Disorder --- Mental Disorder, Severe --- Mental Illnesses --- Psychiatric Disease --- Psychiatric Disorder --- Psychiatric Illnesses --- Severe Mental Disorder --- Severe Mental Disorders --- Mentally Ill Persons --- Congresses --- physiology --- Sleep Deprivation. --- Transportation. --- prevention & control. --- Transport. Traffic --- Personnel management

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Biomedicine is a multidisciplinary branch of medical science that consists of many scientific disciplines, e.g., biology, biotechnology, bioinformatics, and genetics; moreover, it covers various medical specialties. In recent years, this field of science has developed rapidly. This means that a large amount of data has been generated, due to (among other reasons) the processing, analysis, and recognition of a wide range of biomedical signals and images obtained through increasingly advanced medical imaging devices. The analysis of these data requires the use of advanced IT methods, which include those related to the use of artificial intelligence, and in particular machine learning. It is a summary of the Special Issue “Machine Learning for Biomedical Application”, briefly outlining selected applications of machine learning in the processing, analysis, and recognition of biomedical data, mostly regarding biosignals and medical images.

Research & information: general --- depthwise separable convolution (DSC) --- all convolutional network (ACN) --- batch normalization (BN) --- ensemble convolutional neural network (ECNN) --- electrocardiogram (ECG) --- MIT-BIH database --- cephalometric landmark --- X-ray --- deep learning --- ResNet --- registration --- electronic human-machine interface --- blindness --- gesture recognition --- inertial sensors --- IMU --- dynamic contrast-enhanced MRI --- kidney perfusion --- glomerular filtration rate --- pharmacokinetic modeling --- multi-layer perceptron --- parameter estimation --- instance segmentation --- computer vision --- retinal blood vessel image --- computer-aided diagnosis --- U-shaped neural network --- residual learning --- semantic gap --- intracranial hemorrhage --- computed tomography --- random forest --- sleep disorder --- obstructive sleep disorder --- overnight polysomnogram --- EEG --- EMG --- ECG --- HRV signals --- Electronic Medical Record (EMR) --- disease prediction --- Amyotrophic Lateral Sclerosis (ALS) --- weighted Jaccard index (WJI) --- lung cancer --- CT images --- CNN --- pulmonary fibrosis --- radiotherapy --- n/a

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Semiotics --- Semiotiek. --- Semiotik. --- Semiotics. --- Semiologie --- Zeichentheorie --- Semeiotics --- Semiology (Linguistics) --- Zeichen --- Semantics --- Signs and symbols --- Structuralism (Literary analysis) --- Linguistique. --- Sémantique. --- Publications périodiques. --- Semiotik --- Sleep Wake Disorders. --- Long Sleeper Syndrome --- Short Sleep Phenotype --- Short Sleeper Syndrome --- Sleep-Related Neurogenic Tachypnea --- Subwakefullness Syndrome --- Sleep Disorders --- Disorder, Sleep --- Disorder, Sleep Wake --- Disorders, Sleep --- Disorders, Sleep Wake --- Long Sleeper Syndromes --- Neurogenic Tachypnea, Sleep-Related --- Neurogenic Tachypneas, Sleep-Related --- Phenotype, Short Sleep --- Phenotypes, Short Sleep --- Short Sleep Phenotypes --- Short Sleeper Syndromes --- Sleep Disorder --- Sleep Phenotypes, Short --- Sleep Related Neurogenic Tachypnea --- Sleep Wake Disorder --- Sleep-Related Neurogenic Tachypneas --- Sleeper Syndrome, Long --- Sleeper Syndrome, Short --- Sleeper Syndromes, Long --- Sleeper Syndromes, Short --- Subwakefullness Syndromes --- Syndrome, Long Sleeper --- Syndrome, Short Sleeper --- Syndrome, Subwakefullness --- Syndromes, Long Sleeper --- Syndromes, Short Sleeper --- Syndromes, Subwakefullness --- Tachypnea, Sleep-Related Neurogenic --- Tachypneas, Sleep-Related Neurogenic --- Wake Disorder, Sleep --- Wake Disorders, Sleep --- Sleep Hygiene --- Comparative linguistics