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An international group of authors have produced an overview of the progress made in the medicinal chemistry of compounds (selectively) acting at serotonin receptors or serotonin transporters either as agonists, partial agonists or antagonists. Structure - affinity relationships and structure - activity relationships of agonists, partial agonists, and antagonists of 5-HT receptors and uptake sites, are discussed. Structure, sequence homology and the effect of site-directed mutations of 5-HT receptors and the reuptake site on the binding of ligands show the tremendous impact of molecular biolo

Serotonin --- Antagonists, Serotonin --- Antiserotonergic agents --- Antiserotonin drugs --- Serotonin antagonists --- Serotonin blockaders --- Serotonin inhibitors --- 5-HT (Neurotransmitter) --- Hydroxytryptamine --- Neurotransmitters --- Tryptamine --- Receptors. --- Agonists. --- Antagonists.