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Reports that heat processing of foods induces the formation of acrylamide heightened interest in the chemistry, biochemistry, and safety of this compound. Acrylamide-induced neurotoxicity, reproductive toxicity, genotoxicity, and carcinogenicity are potential human health risks based on animal studies. Because exposure of humans to acrylamide can come from both external sources and the diet, there exists a need to develop a better understanding of its formation and distribution in food and its role in human health. To contribute to this effort, experts from eight countries have presented data on the chemistry, analysis, metabolism, pharmacology, and toxicology of acrylamide. Specifically covered are the following aspects: exposure from the environment and the diet; biomarkers of exposure; risk assessment; epidemiology; mechanism of formation in food; biological alkylation of amino acids, peptides, proteins, and DNA by acrylamide and its epoxide metabolite glycidamide; neurotoxicity, reproductive toxicity, and carcinogenicity; protection against adverse effects; and possible approaches to reducing levels in food. Cross-fertilization of ideas among several disciplines in which an interest in acrylamide has developed, including food science, pharmacology, toxicology, and medicine, will provide a better understanding of the chemistry and biology of acrylamide in food, and can lead to the development of food processes to decrease the acrylamide content of the diet.

Acrylamide --- Food --- Toxicology. --- Food toxicology --- Nutritional toxicology --- Toxicology --- Nutritionally induced diseases --- Acrylic amide --- Propenamide --- Propenoic acid amide --- Acrylates --- Amides --- Food science. --- Chemistry. --- Food Science. --- Chemistry/Food Science, general. --- Physical sciences --- Science --- Food technology --- Chemical engineering --- Food Technology. --- Food Sciences --- Technology, Food --- Food Science --- Science, Food --- Sciences, Food --- Nutritional Sciences

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Food --- Food Technology. --- Nutritional Sciences. --- Food industry and trade. --- Foods --- Dinners and dining --- Home economics --- Table --- Cooking --- Diet --- Dietaries --- Gastronomy --- Nutrition --- Nutrition Science --- Nutrition Sciences --- Nutritional Science --- Science, Nutrition --- Science, Nutritional --- Sciences, Nutrition --- Sciences, Nutritional --- Food Technology --- Food Sciences --- Technology, Food --- Food Science --- Science, Food --- Sciences, Food --- Nutritional Sciences --- Technology --- Agriculture. Animal husbandry. Hunting. Fishery --- food science --- nutrition --- health --- biotechnology

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Food industry and trade --- Food --- Food Industry --- Food Technology --- Biotechnology --- trends --- Aliments --- Industrie et commerce --- Périodiques. --- Biotechnologie --- Food Industries --- Industries, Food --- Industry, Food --- Food Sciences --- Technology, Food --- Food Science --- Science, Food --- Sciences, Food --- Foods --- Nutritional Sciences --- Dinners and dining --- Home economics --- Table --- Cooking --- Diet --- Dietaries --- Gastronomy --- Nutrition --- trends. --- Primitive societies

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Fermentation --- Bioengineering --- Microbiology --- Biomedical Engineering. --- Fermentation. --- Food Technology. --- Microbiological Techniques. --- Biotechnologie --- Microbiologie industrielle --- Biotechnologie. --- Forschung und Entwicklung. --- Japan. --- Food Sciences --- Technology, Food --- Food Science --- Science, Food --- Sciences, Food --- Microbiologic Technic --- Microbiologic Technics --- Microbiologic Technique --- Microbiological Technics --- Technic, Microbiologic --- Technics, Microbiological --- Technique, Microbiologic --- Techniques, Microbiologic --- Microbiologic Techniques --- Microbiological Technic --- Microbiological Technique --- Technic, Microbiological --- Technics, Microbiologic --- Technique, Microbiological --- Techniques, Microbiological --- Fermentations --- Engineering, Biomedical --- Clinical Engineering --- Engineering, Clinical --- methods --- Nutritional Sciences --- Bioreactors --- Biomedical Technology

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Food industry and trade --- Food Technology --- Food --- Food-Processing Industry --- Aliments --- Industrie et commerce --- Périodiques. --- Recherche --- Industry, Food-Processing --- Food Processing Industry --- Food-Processing Industries --- Industries, Food-Processing --- Industry, Food Processing --- Nutrients --- Foods --- Food Sciences --- Technology, Food --- Food Science --- Science, Food --- Sciences, Food --- Food preparation industry --- Food processing industry --- Food trade --- Nutrient --- Nutritional Physiological Phenomena --- Nutritional Requirements --- Nutritional Sciences --- Agricultural processing industries --- Processed foods --- Food processing --- Food technology --- Processing --- Food Technology. --- Food. --- Food-Processing Industr. --- Food-Processing Industry.