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Streptococcus agalactiae --- Streptococcus agalactiae --- Streptococcus agalactiae --- chemistry. --- genetics. --- immunology.
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Résumé
STREPTOCOCCUS AGALACTIAE --- GENETICS --- STREPTOCOCCUS AGALACTIAE --- GENETICS
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STREPTOCOCCUS AGALACTIAE --- GENETICS --- STREPTOCOCCUS AGALACTIAE --- GENETICS
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Pregnancy --- Streptococcus agalactiae --- Streptococcal infections --- Complications --- Prevention.
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Streptococcal Infections --- Streptococcus agalactiae --- Pregnancy Complications, Infectious --- transmission --- growth & development
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Le Streptocoque du groupe B, également appelé Streptococcus agalactiae ou Group B Streptococcus (GBS), est une bactérie cocci à gram positif, présente naturellement dans le tractus gastro-intestinal et génital des porteurs sains. Ce pathogène opportuniste est responsable de la première cause d’infection néonatale chez les nouveau-nés. Elle se manifeste principalement par des septicémies et des méningites. Ce travail de fin d’études s’inscrit dans le cadre de l’évaluation d’une nouvelle méthode de typage basée sur le séquençage à haut débit, ou « Next Generation Sequencing » (NGS). Ce dernier, combiné à l’outil bioinformatique « WGS typer », permet une caractérisation complète de la bactérie. L’objectif de ce TFE repose ainsi sur une comparaison entre les méthodes actuellement utilisées au laboratoire (PCR et MLST) et la nouvelle approche. Les facteurs ciblés sont le sérotype capsulaire, les protéines pili, les gènes de résistance et le « sequence type ». Les résultats obtenus pour les 37 souches étudiées sont majoritairement similaires entre les deux démarches. Au vu des avantages du NGS, il fera prochainement l’objet d’une validation de méthode au sein du Centre National de Référence du GBS.
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STREPTOCOCCUS AGALACTIAE --- DELIVERY --- STREPTOCOCCAL INFECTIONS --- INFANT, NEWBORN --- MOTHERS --- VAGINAL SMEARS --- ANTIBIOTICS --- PREVENTION AND CONTROL --- THERAPEUTIC USE --- STREPTOCOCCUS AGALACTIAE --- DELIVERY --- STREPTOCOCCAL INFECTIONS --- INFANT, NEWBORN --- MOTHERS --- VAGINAL SMEARS --- ANTIBIOTICS --- PREVENTION AND CONTROL --- THERAPEUTIC USE
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Gelber Galt. --- Mastitis (Veterinärmedizin) --- Rindererkrankungen --- Serodiagnostik --- Streptococcus agalactiae --- Streptokokkendifferenzierung b. Rinder. --- Kreuzreaktionen v. B-Streptokokken v. Mensch u. Rind. --- B-Streptokokken b. Rindern u. b. Menschen. --- Pathogenität f. Mensch u. Rind.
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Phages have shown a high biotechnological potential with numerous applications. The advent of high-resolution microscopy techniques aligned with omic and molecular tools have revealed innovative phage features and enabled new processes that can be further exploited for biotechnological applications in a wide variety of fields. The high-quality original articles and reviews presented in this Special Issue demonstrate the incredible potential of phages and their derived proteins in a wide range of biotechnological applications for human benefit. Considering the emergence of amazing new available bioengineering tools and the high abundance of phages and the multitude of phage proteins yet to be discovered and studied, we believe that the upcoming years will present us with many more fascinating and new previously unimagined phage-based biotechnological applications.
toxicity --- encapsulation --- n/a --- cancerous tumors --- bacteriophage-derived lytic enzyme --- native gel electrophoresis --- bacteriophages --- Cpl-1 --- O-antigen --- ESKAPE --- Clostridium perfringens --- X-ray crystallography --- macromolecular interactions --- safety --- biofilm --- major coat protein --- Streptococcus agalactiae --- Staphylococcus aureus --- tail sheath protein --- magnetic separation --- serotyping --- pathogenic viruses --- liposomes --- tuberculosis --- Listeria monocytogenes --- nanotubular structures --- alpha-sheet --- biosensors --- sarcoidosis --- tailspike proteins --- M13 bacteriophage --- Streptococcus pneumoniae --- gene expression regulation --- bacteriophage recombination --- self-assembly --- phage therapy --- R-type pyocin --- contractile injection systems --- bacteriophage vB_EcoM_FV3 --- microtiter plate assay --- Enterococcus faecalis --- culture enrichment --- drug delivery vehicles --- neurodegenerative disease --- landscape phage --- niosomes --- bacteriophage --- Myoviridae --- bacteriophage evolution --- porous structure --- phage-host interaction --- phage display --- immune response --- antibiotic resistance --- Pseudomonas aeruginosa --- phage --- bacteriocin --- Appelmans --- fluorescence sensor --- molecular probe --- nanomedicine --- Shigella flexneri --- reporter phage --- filters --- in vitro activity --- capsid dynamics --- immunoscreening --- diagnostics --- microarray --- receptor-binding protein --- endolysin --- enzybiotics --- transfersomes --- T7phage library --- Pal
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