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Orthodox Eastern Church --- Srpska pravoslavna crkva --- History --- Herzegovina (Bosnia and Herzegovina) --- Church history --- Biserica Ortodoxă Sârbă --- Eglise orthodoxe serbe --- Orthodox Church of Serbia --- Orthodox Eastern Church. --- Serbian Orthodox Church --- Serbische Orthodoxe Kirche --- Srp. prav. crkva --- Srpska crkva --- Српска православна црква --- Hercegovina (Bosnia and Hercegovina) --- Hum (Bosnia and Herzegovina) --- Zahumlje (Bosnia and Herzegovina) --- Serbs --- Religion --- Serbians --- Serbo-Croatians --- Servians --- Ethnology
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Bishop Nikolaj Velimirović (1881–1956) is arguably one the most controversial figures in contemporary Serbian national culture. Having been vilified by the former Yugoslav Communist authorities as a fascist and an antisemite, this Orthodox Christian thinker has over the past two decades come to be regarded in Serbian society as the most important religious person since medieval times and an embodiment of the authentic Serbian national spirit. Velimirović was formally canonised by the Serbian Orthodox Church in 2003. In this book, Jovan Byford charts the posthumous transformation of Velimirović from 'traitor' to 'saint' and examines the dynamics of repression and denial that were used to divert public attention from the controversies surrounding the bishop's life, the most important of which is his antisemitism. Byford offers the first detailed examination of the way in which an Eastern Orthodox Church manages controversy surrounding the presence of antisemitism within its ranks and he considers the implications of the continuing reverence of Nikolaj Velimirović for the persistence of antisemitism in Serbian Orthodox culture and in Serbian society as a whole. This book is based on a detailed examination of the changing representation of Bishop Nikolaj Velimirović in the Serbian media and in commemorative discourse devoted to him. The book also makes extensive use of exclusive interviews with a number of Serbian public figures who have been actively involved in the bishop’s rehabilitation over the past two decades.
Velimirović, Nikolaj, --- Srpska pravoslavna crkva --- Nikolaj, --- Velimirović, Nik., --- Nikolaĭ, --- Velimirović, Nicholas, --- Vel-Mirovich, Nicholas, --- Velimirovic, Nicholai, --- Velimirovic, Nicolai, --- Velimirovich, Nicholai --- Велимировић, Николај, --- Sveti Nikolaj Srpski, --- Eglise orthodoxe serbe --- Orthodox Church of Serbia --- Serbian Orthodox Church --- Serbische Orthodoxe Kirche --- Srp. prav. crkva --- Srpska crkva --- Српска православна црква --- Christian saints --- Orthodox Eastern Church --- Bishops --- Orthodox Eastern Church. --- Biserica Ortodoxă Sârbă --- 20th century, Biography, Media, Memory politics, Orthodox Church, Saints, Serbia. --- Velimirovic, Nikolaj,
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Focusing on the impact of the Savannah River Plant (SRP) on the communities it created, rejuvenated, or displaced, this book explores the parallel militarization and modernization of the Cold War-era South. The SRP, a scientific and industrial complex near Aiken, South Carolina, grew out of a 1950 partnership between the Atomic Energy Commission and the DuPont Corporation and was dedicated to producing materials for the hydrogen bomb. Kari Frederickson shows how the needs of the expanding national security state, in combination with the corporate culture of DuPont, transformed the economy, lan
Social change --- Militarism --- Nuclear weapons industry --- Cold War --- World politics --- Weapons industry --- Antimilitarism --- Military policy --- Sociology, Military --- Chauvinism and jingoism --- Imperialism --- Change, Social --- Cultural change --- Cultural transformation --- Societal change --- Socio-cultural change --- Social history --- Social evolution --- History --- Social aspects --- Savannah River Plant (E.I. du Pont de Nemours & Company) --- Savannah River Site (Westinghouse Savannah River Company) --- Du Pont de Nemours (E. I.) and Company. --- E.I. du Pont de Nemours & Company. --- SRP --- History. --- Aiken (S.C.) --- Savannah River Valley (Ga. and S.C.) --- Savannah Valley (Ga. and S.C.) --- City of Aiken (S.C.) --- Economic conditions --- Social conditions --- Cold war
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This book is a comprehensive exposition of the interaction of a national (the Serbian people) and a religiou (the Orthodox Christian faith) content, in the formation of a distinctive national identity and a mode of being. Its interdisciplinary approach, drawing on sociology, social anthropology, theology, political theory, Balkan historiography, and Serbian folklore, is deployed to provide a powerful and original analysis of how Serbian Orthodoxy has resulted in the sacralisation of the Serbian nation by framing the parameters of its existence. Addresses the following questions: what 'makes' a Serb? Are meaningful assumptions possible by introducing Serbian Orthodoxy as the primal point of reference? Why does religion appear to have an especially strong appeal?
Church and state --- Nationalism --- Christianity and state --- Separation of church and state --- State and church --- State, The --- Consciousness, National --- Identity, National --- National consciousness --- National identity --- International relations --- Patriotism --- Political science --- Autonomy and independence movements --- Internationalism --- Political messianism --- History. --- Srpska pravoslavna crkva --- Religious aspects --- History of doctrines. --- Biserica Ortodoxă Sârbă --- Eglise orthodoxe serbe --- Orthodox Church of Serbia --- Orthodox Eastern Church. --- Serbian Orthodox Church --- Serbische Orthodoxe Kirche --- Srp. prav. crkva --- Srpska crkva --- Српска православна црква --- Serbia --- N.R. Serbii︠a︡ --- Narodna Republika Srbija --- NR Serbii︠a︡ --- People's Republic of Serbia --- Republic of Serbia --- Republika Srbija --- RS de Serbije --- Serbii︠a︡ --- Servia --- Socialist Republic of Serbia --- Socijalistička Republika Srbija --- Sot︠s︡ialisticheskai︠a︡ Respublika Serbii︠a︡ --- SR Srbija --- Srbija --- SRS --- Szerbia --- Србија --- Serbia and Montenegro --- Church history. --- Religious life and customs. --- Balkan, Identity, Nationalism, Orthodox Church, Religion, Serbia.
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Protein import into the endoplasmic reticulum (ER) is the first step in the biogenesis of approximately 10,000 different soluble and membrane proteins of human cells, which amounts to about 30% of the proteome. Most of these proteins fulfill their functions either in the membrane or lumen of the ER plus the nuclear envelope, in one of the organelles of the pathways for endo- and exocytosis (ERGIC, Golgi apparatus, endosome, lysosome, and trafficking vesicles), or at the cell surface as plasma membrane or secreted proteins. An increasing number of membrane proteins destined to lipid droplets, peroxisomes or mitochondria are first targeted to and inserted into the ER membrane prior to their integration into budding lipid droplets or peroxisomes or prior to their delivery to mitochondria via the ER-SURF pathway. ER protein import involves two stages, ER targeting, which guarantees membrane specificity, and the insertion of nascent membrane proteins into or translocation of soluble precursor polypeptides across the ER membrane. In most cases, both processes depend on amino-terminal signal peptides or transmembrane helices, which serve as signal peptide equivalents. However, the targeting reaction can also involve the ER targeting of specific mRNAs or ribosome–nascent chain complexes. Both processes may occur co- or post-translationally and are facilitated by various sophisticated machineries, which reside in the cytosol and the ER membrane, respectively. Except for resident ER and mitochondrial membrane proteins, the mature proteins are delivered to their functional locations by vesicular transport.
chaperones --- contact sites --- endoplasmic reticulum --- ER-SURF --- membrane extraction --- mitochondria --- protein targeting --- bimolecular luminescence complementation --- competition --- split luciferase --- membrane proteins --- protein–protein interactions --- Sec61 complex --- Sec63 --- synthetic peptide complementation --- TRAP complex --- ER protein translocase --- signal peptide --- protein translocation --- nascent peptide chain --- membrane insertion --- molecular modelling --- molecular dynamics simulations --- molecular docking --- signal peptidase --- ER translocon --- signal recognition particle dependent protein targeting --- Sec61 dependent translocation --- co-translational translocation --- inhibitor --- high throughput screening --- Sec61 --- Sec62 --- folding --- insertion --- membrane protein --- translocon --- ribosome --- transmembrane segment --- lipid droplets --- peroxisomes --- PEX3 --- membrane protein insertion --- label-free quantitative mass spectrometry --- differential protein abundance analysis --- Zellweger syndrome --- GET --- protein transport --- SND --- SRP --- EMC --- positive-inside rule --- hydrophobicity --- transmembrane helix --- signal recognition particle --- nascent polypeptide-associated complex --- fidelity --- cyclotriazadisulfonamide --- ER quality control --- DNAJC3 --- preprotein --- Sec61 translocon --- ribosome stalling --- signal sequence --- Sec61 translocase --- NAC --- n/a --- protein-protein interactions
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The book explores issues concerning the design, synthetic methods and biological evaluation of molecules of pharmaceutical interest.
fluorinated pyrazole aldehydes --- tyrosinase inhibition --- phosphodiesterase inhibition --- antibacterial activity --- molecular docking --- periodontitis --- SRP --- LDD --- gelcide --- cancer --- phytocomponents --- Tiospora cardifolia --- silica --- silver oxynitrate --- stability --- core-shell --- antibiofilm --- antimicrobial --- sesquiterpene --- inflammatory pathologies --- nutraceuticals --- triclosan --- surgical site infection --- suture --- abdominal surgery --- cost-analysis --- budget impact analysis --- spirooxindole --- 1,3-dipolar cycloaddition --- eco-friendly chemistry --- ROCS --- shape alignment --- lipophilicity --- anticancer activity --- sol–gel coating --- medical textiles --- antioxidant --- anti-inflammatory --- PEA derivative --- drug release --- imidazole --- antiproliferative --- antioxidant activities --- docking --- DPPH --- ABTS --- acetylcholinesterase --- xanthine oxidase --- pyrimidine-trione --- barbituric --- thiobarbituric --- urease inhibitors --- DFT --- N-benzylisatin-aryl hydrazones --- gefitinib --- A549 cell lines --- pomegranate --- Punica granatum L. --- pomegranate skin extract --- pomegranate fruit extract --- nutraceutical properties --- biological properties --- cladodes --- Opuntia --- antioxidants --- polyphenols --- SFE-CO2 --- rutin --- iso-quercitrin --- nicotiflorin --- narcissin --- n/a --- sol-gel coating
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Protein import into the endoplasmic reticulum (ER) is the first step in the biogenesis of approximately 10,000 different soluble and membrane proteins of human cells, which amounts to about 30% of the proteome. Most of these proteins fulfill their functions either in the membrane or lumen of the ER plus the nuclear envelope, in one of the organelles of the pathways for endo- and exocytosis (ERGIC, Golgi apparatus, endosome, lysosome, and trafficking vesicles), or at the cell surface as plasma membrane or secreted proteins. An increasing number of membrane proteins destined to lipid droplets, peroxisomes or mitochondria are first targeted to and inserted into the ER membrane prior to their integration into budding lipid droplets or peroxisomes or prior to their delivery to mitochondria via the ER-SURF pathway. ER protein import involves two stages, ER targeting, which guarantees membrane specificity, and the insertion of nascent membrane proteins into or translocation of soluble precursor polypeptides across the ER membrane. In most cases, both processes depend on amino-terminal signal peptides or transmembrane helices, which serve as signal peptide equivalents. However, the targeting reaction can also involve the ER targeting of specific mRNAs or ribosome–nascent chain complexes. Both processes may occur co- or post-translationally and are facilitated by various sophisticated machineries, which reside in the cytosol and the ER membrane, respectively. Except for resident ER and mitochondrial membrane proteins, the mature proteins are delivered to their functional locations by vesicular transport.
Research & information: general --- Biology, life sciences --- chaperones --- contact sites --- endoplasmic reticulum --- ER-SURF --- membrane extraction --- mitochondria --- protein targeting --- bimolecular luminescence complementation --- competition --- split luciferase --- membrane proteins --- protein-protein interactions --- Sec61 complex --- Sec63 --- synthetic peptide complementation --- TRAP complex --- ER protein translocase --- signal peptide --- protein translocation --- nascent peptide chain --- membrane insertion --- molecular modelling --- molecular dynamics simulations --- molecular docking --- signal peptidase --- ER translocon --- signal recognition particle dependent protein targeting --- Sec61 dependent translocation --- co-translational translocation --- inhibitor --- high throughput screening --- Sec61 --- Sec62 --- folding --- insertion --- membrane protein --- translocon --- ribosome --- transmembrane segment --- lipid droplets --- peroxisomes --- PEX3 --- membrane protein insertion --- label-free quantitative mass spectrometry --- differential protein abundance analysis --- Zellweger syndrome --- GET --- protein transport --- SND --- SRP --- EMC --- positive-inside rule --- hydrophobicity --- transmembrane helix --- signal recognition particle --- nascent polypeptide-associated complex --- fidelity --- cyclotriazadisulfonamide --- ER quality control --- DNAJC3 --- preprotein --- Sec61 translocon --- ribosome stalling --- signal sequence --- Sec61 translocase --- NAC
Choose an application
The book explores issues concerning the design, synthetic methods and biological evaluation of molecules of pharmaceutical interest.
Research & information: general --- Chemistry --- fluorinated pyrazole aldehydes --- tyrosinase inhibition --- phosphodiesterase inhibition --- antibacterial activity --- molecular docking --- periodontitis --- SRP --- LDD --- gelcide --- cancer --- phytocomponents --- Tiospora cardifolia --- silica --- silver oxynitrate --- stability --- core-shell --- antibiofilm --- antimicrobial --- sesquiterpene --- inflammatory pathologies --- nutraceuticals --- triclosan --- surgical site infection --- suture --- abdominal surgery --- cost-analysis --- budget impact analysis --- spirooxindole --- 1,3-dipolar cycloaddition --- eco-friendly chemistry --- ROCS --- shape alignment --- lipophilicity --- anticancer activity --- sol-gel coating --- medical textiles --- antioxidant --- anti-inflammatory --- PEA derivative --- drug release --- imidazole --- antiproliferative --- antioxidant activities --- docking --- DPPH --- ABTS --- acetylcholinesterase --- xanthine oxidase --- pyrimidine-trione --- barbituric --- thiobarbituric --- urease inhibitors --- DFT --- N-benzylisatin-aryl hydrazones --- gefitinib --- A549 cell lines --- pomegranate --- Punica granatum L. --- pomegranate skin extract --- pomegranate fruit extract --- nutraceutical properties --- biological properties --- cladodes --- Opuntia --- antioxidants --- polyphenols --- SFE-CO2 --- rutin --- iso-quercitrin --- nicotiflorin --- narcissin
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