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Flavins --- Flavoproteins --- Congresses --- Flavins. --- Proteins. --- 577.164.1 <063> --- -Flavoproteins --- -Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Molecular Mechanisms of Pharmacological Action --- Flavoenzymes --- Proteins --- Lyochromes --- Coenzymes --- Pigments (Biology) --- Vitamin B complex or group (Thiamin. Aneurin. Riboflavin. Lactoflavin. Folic acid etc.)--Congressen --- Conferences - Meetings --- Congresses. --- -Vitamin B complex or group (Thiamin. Aneurin. Riboflavin. Lactoflavin. Folic acid etc.)--Congressen --- 577.164.1 <063> Vitamin B complex or group (Thiamin. Aneurin. Riboflavin. Lactoflavin. Folic acid etc.)--Congressen --- Gene Products, Protein --- Protein --- Flavins - Congresses --- Flavoproteins - Congresses

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This Special Issue provides an update on the most recent research and developments in the area of freeze-drying technology in foods. It presents a combination of experimental and modeling studies, offering an overview of oncoming challenges and opportunities on the topic.

Technology: general issues --- aquafaba --- chickpea --- emulsifiers --- egg replacer --- egg-free products --- vitamin C --- total phenols --- total carotenoids --- antioxidant activity --- colour --- mechanical properties --- pressure --- shelf temperature --- freezing rate --- freeze-drying --- lyophilization --- plant-based foods --- fruits --- vegetables --- blueberry freeze-drying --- berry-busting --- skin perforation --- primary drying time --- quality --- gellan gum --- modified pH --- riboflavin --- drying kinetics --- release mechanism --- model discrimination --- process design --- rehydration --- modelling --- microstructure --- food quality --- encapsulation --- processes combination --- aquafaba --- chickpea --- emulsifiers --- egg replacer --- egg-free products --- vitamin C --- total phenols --- total carotenoids --- antioxidant activity --- colour --- mechanical properties --- pressure --- shelf temperature --- freezing rate --- freeze-drying --- lyophilization --- plant-based foods --- fruits --- vegetables --- blueberry freeze-drying --- berry-busting --- skin perforation --- primary drying time --- quality --- gellan gum --- modified pH --- riboflavin --- drying kinetics --- release mechanism --- model discrimination --- process design --- rehydration --- modelling --- microstructure --- food quality --- encapsulation --- processes combination

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This Special Issue provides an update on the most recent research and developments in the area of freeze-drying technology in foods. It presents a combination of experimental and modeling studies, offering an overview of oncoming challenges and opportunities on the topic.

Technology: general issues --- aquafaba --- chickpea --- emulsifiers --- egg replacer --- egg-free products --- vitamin C --- total phenols --- total carotenoids --- antioxidant activity --- colour --- mechanical properties --- pressure --- shelf temperature --- freezing rate --- freeze-drying --- lyophilization --- plant-based foods --- fruits --- vegetables --- blueberry freeze-drying --- berry-busting --- skin perforation --- primary drying time --- quality --- gellan gum --- modified pH --- riboflavin --- drying kinetics --- release mechanism --- model discrimination --- process design --- rehydration --- modelling --- microstructure --- food quality --- encapsulation --- processes combination

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The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment, suitably designed to be a similar as possible to cellular conditions. This Special Issue provides readers with a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to be used as traces for the discoveries of some relevant biological processes. Several subjects are presented, with five articles and five reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications and bioinspired synthesis, with “free radicals” as the common denominator.

guanine --- guanyl radical --- tautomerism --- guanine radical cation --- oligonucleotides --- DNA --- G-quadruplex --- time-resolved spectroscopies --- reactive oxygen species (ROS) --- oxidation --- catalase mimics --- peroxide --- diiron-peroxo complexes --- structure/activity --- kinetic studies --- biomimetic chemistry --- cysteine --- ketone reduction --- free radicals --- pulse radiolysis --- kinetics --- DNA oxidation --- DNA hole transfer --- molecular dynamics --- quantum dynamics --- electron transfer --- charge transfer --- quantum coherence --- chemiluminescence --- reaction mechanisms --- singlet oxygen --- reactive oxygen species --- light emission --- crosslink --- dimerization --- protein oxidation --- radicals --- di-tyrosine --- di-tryptophan --- disulfides --- thiols --- aggregation --- proteomics --- mass spectrometry --- collagen --- riboflavin --- hyaluronic acid --- EPR spectroscopy --- keratoconus --- STEM --- DNA biosensor --- chemical nucleases --- DNA-drug interaction --- copper complexes --- metallodrugs --- MEP pathway --- antibiotics --- IspH --- LytB --- [4Fe-4S] cluster --- reductive dehydroxylation --- bioorganometallic intermediate --- inhibitors --- methionine --- neighboring group effect --- hydroxyl radical --- triplet state of carboxybenzophenone --- one-electron oxidants --- laser flash photolysis --- peptides --- proteins --- n/a

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This special issue brings together cutting edge research and insightful commentary on the currentl state of the Cancer Nanomedicine field.

Technology: general issues --- antibody drug conjugate (ADC) --- PD-L1 --- tumor spheroid disruption --- immune modulation --- doxorubicin --- graphene oxide --- adsorption --- cathepsin D --- cathepsin L --- anti-metastatic enzyme cancer therapy --- nanoparticles --- targeted delivery system --- siRNA --- osteopontin --- mammary carcinoma --- mesenchymal stem cells (MSCs) --- TAT peptide --- PLGA --- paclitaxel --- nano-engineered MSCs --- orthotopic lung tumor model --- intracranial glioma --- immunotherapy --- CPMV --- viral nanoparticles --- in situ vaccine --- albumin nanoparticles --- microbubble --- ultrasound --- theranostics --- hepatocellular carcinoma --- VX2 tumor --- intra-arterial chemotherapy --- lung cancer --- nanomedicine --- clinical status --- cancer therapy --- breast cancer --- cell signaling --- active targeting --- passive targeting --- EPR effect --- oncogenes --- nanoparticle --- drug delivery --- ligand --- tumor targeting --- biodistribution --- Mesoporous silica nanoparticle --- drug delivery system --- target treatment --- lanthanide metal --- hyaluronic acid --- hyaluronidase --- drug combination --- everolimus --- dual-targeting --- magnetic nanoparticles --- monoclonal antibodies --- nanostructured lipid carrier --- platelet membrane --- biomimicry --- plasmonic photothermal therapy --- gold nanorods --- surgery --- bleeding --- dogs --- cats --- stimuli-responsive --- DOX --- SN38 --- CSCs --- single-walled carbon nanotubes --- chirality separation --- NASH --- drug-gene delivery --- near IR hyperspectral imaging --- plasmonics --- copper --- VEGF --- glioblastoma --- differentiated neuroblastoma --- peptidomimetics --- real-time quantitative polymerase chain reaction (qPCR) --- actin --- combinatorial therapy --- anticancer and antibacterial activity --- temoporfin --- drug-in-cyclodextrin-in-liposome --- hybrid nanoparticles --- multicellular tumor spheroids --- cyclodextrins --- photodynamic therapy article --- yet reasonably common within the subject discipline --- antitumor strategy --- biomimetic core–shell nanoparticles --- NK cell-derived exosomes --- folate receptor --- albumin nanoparticle --- microfluidic --- cabazitaxel --- polydopamine nanoparticles --- size --- cytotoxicity --- iron affinity --- FA-DABA-SMA --- self-assembly --- oncogenic proteins --- intracellular disruption --- folic receptor alpha --- pancreatic cancer --- parvifloron D --- albumin --- erlotinib --- photodynamic therapy --- lipid nanoparticles --- tumor vectorization --- verteporfin --- ovarian carcinomatosis --- spheroids --- integrin --- RGD peptide --- cancer diagnosis --- radiotherapy --- hyperthermia therapy --- biomimetic --- nanocarrier --- membrane-wrapped --- cancer --- targeted delivery --- photothermal therapy --- imaging --- cancer nanomedicine --- tumor microenvironment --- nano–bio interactions --- clinical translation --- magnetic nanowires --- magnetic hyperthermia --- magnetic actuation --- magnetic drug targeting --- titanate nanotubes --- gold nanoparticles --- vectorization --- colloidal stability --- docetaxel --- prostate cancer --- mangiferin --- anti-topoisomerase activity --- extracellular vesicles --- exosomes --- chemico-physical functionalization --- loading --- translational medicine --- nanotechnology: bioengineering --- anacardic acid --- mitoxantrone --- targeted drug delivery --- liposomes --- melanoma --- apoptosis --- ascorbic acid --- angiogenesis --- epithelial-to-mesenchymal transition --- hypoxia --- immunosuppression --- metabolism --- nanotherapeutics --- tumour microenvironment --- DNA origami --- liposome --- remote loading --- acute toxicity --- organoids --- magnetic silica-coated iron oxide nanochains --- photothermal treatment --- hyperthermia --- collagen --- cellular microenvironment --- lymphadenectomy --- magnetometer --- sentinel lymph node dissection --- SPION --- superparamagnetic iron oxide nanoparticles --- Vδ2 T cells --- zoledronic acid --- polymeric nanoconstruct --- anti-tumor immunity --- colorectal carcinoma --- β-cyclodextrin nanosponges --- BALB-neuT mice --- brain tumours --- glioma --- blood brain barrier --- polymeric nanoparticles --- PEGylation --- dioleoylphosphatidylethanolamine --- poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer --- folate --- oxidation-sensitive release --- cellular interaction --- in vitro anti-cancer activity --- triple negative breast cancer --- organotin --- mesoporous silica nanoparticles --- MDA-MB-231 --- theranostic nanomaterials --- nanobiotechnology --- molecular imaging --- nanosystems --- nanomicelles --- ovarian cancer --- tumour targeting --- chemotherapeutics --- riboflavin --- vitamin B2 --- nanomedicines --- secondary structure --- mixed micelle --- pH responsive --- targeted therapy --- anti-cancer --- shear stress --- flow --- in vitro --- therapeutics --- diagnostics --- Immunotherapy