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It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. This includes a discussion of presynaptic calcium channels, the core proteins of the secretory machinery, and the actions of clostridial toxins and a -latrotoxin, famous for their potency as well as their crucial role in the elucidation of the steps of exocytosis. In the book’s second part, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process. These include ligand-gated ion channels and presynaptic G-protein-coupled receptors. The targets of presynaptic receptors within the exocytosis cascade, and their therapeutic potential, are subjects addressed in the majority of chapters.

Exocytosis. --- Neurotransmitter receptors. --- Neurotransmitters. --- Chemical nerve transmitters --- Nerve transmitter substances --- Neural transmitters --- Neurohumors --- Neuroregulators --- Synaptic transmitters --- Transmitters, Chemical nerve --- Transmitters, Synaptic --- Neurochemistry --- Neural transmission --- Receptors, Neurotransmitter --- Cell receptors --- Hormone receptors --- Neural receptors --- Reverse pinocytosis --- Cell physiology --- Toxicology. --- Neurosciences. --- Neurology. --- Human physiology. --- Pharmacology/Toxicology. --- Human Physiology. --- Human biology --- Medical sciences --- Physiology --- Human body --- Medicine --- Nervous system --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Neuroscience --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Diseases --- Toxicology --- Pharmacology. --- Neurology . --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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Mutant --- Mutants --- Plante --- plants --- Méthode d'amélioration génétique --- breeding methods --- Mutation --- mutation --- 581.14 --- 581.15 --- Coated vesicles --- Endocytosis --- Exocytosis --- Plant cells and tissues --- -Plant mutation --- -Plant translocation --- Plants --- #WPLT:dd.prof.J.Vendrig --- Flora --- Plant kingdom --- Plantae --- Vascular plants --- Vegetable kingdom --- Vegetation --- Wildlife --- Organisms --- Botany --- Translocation (Botany) --- Translocation in plants --- Biological transport --- Plants, Motion of fluids in --- Mutation of plants --- Mutation (Biology) --- Plant genetics --- Plant tissues --- Cells --- Plant anatomy --- Tissues --- Reverse pinocytosis --- Cell physiology --- Absorption (Physiology) --- Vesicles, Coated --- Cell organelles --- Development --- Variations. Modifications. Mutations --- Inclusions --- Congresses --- -Congresses. --- Translocation --- Assimilation --- Metabolism --- Coated vesicles. --- Endocytosis. --- Exocytosis. --- Plant mutation --- Plant translocation. --- Inclusions. --- Congresses. --- 581.15 Variations. Modifications. Mutations --- 581.14 Development --- Plant and Crop Sciences. Botany -- Plant Development --- ALLW. --- Plant and Crop Sciences Botany -- Plant Development. --- Phytohistology. Phytocytology --- mutation. --- Development -&delete& --- -Congresses --- PLANT CELLS --- ENDOCYTOSIS --- EXOCYTOSIS --- CYTOPLASMIC INCLUSIONS --- COATED VESICLES --- VESICLES --- TRAFFIC --- MEETINGS