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Radioisotope brachytherapy.

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This dissertation by Vaiva Kaveckyte explores the development of experimental brachytherapy dosimetry using Monte Carlo simulations for detector evaluation. Brachytherapy is a cancer treatment method involving the placement of radioactive sources close to or inside a tumor. The research focuses on improving dosimetry accuracy, especially for prostate and gynecological tumors, by proposing a synthetic diamond detector for in-phantom quality assurance. The study examines the detector's suitability for measuring absorbed doses in brachytherapy and external beam radiotherapy, aiming to enhance treatment safety and precision. The work is intended for medical professionals and researchers in the field of radiation therapy.

Radiation dosimetry. --- Radioisotope brachytherapy.

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Radioisotope brachytherapy. --- Cancer --- Treatment.

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Radioisotope brachytherapy --- Accidents

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This thesis by Björn Morén focuses on the mathematical modeling of dose planning in high dose-rate brachytherapy, a form of radiation therapy used primarily in the treatment of prostate and gynecologic cancers. The study addresses the optimization of treatment planning, including decisions on catheter placement and radiation source dwell times, with the aim of maximizing tumor dose while minimizing exposure to surrounding healthy tissues. The research emphasizes the use of dosimetric indices derived from dose-volume histograms to evaluate treatment plans. The work highlights the advantages of mathematical optimization over manual planning, such as reduced planning time and improved treatment quality. Intended for researchers and practitioners in the field of medical physics and oncology, the thesis also discusses the challenges associated with solving mixed-integer programs that incorporate clinically relevant criteria.

Radioisotope brachytherapy. --- Radiation dosimetry.