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Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements, responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation.
RNA-protein interactions. --- Messenger RNA. --- Genetic regulation. --- Prokaryotes. --- Cell organelles. --- Interactions ARN-protéines --- ARN messager --- Régulation génétique --- Procaryotes --- Organites cellulaires --- Bacteria. --- Organelles,. --- RNA Stability. --- RNA, Archaeal. --- RNA, Bacterial. --- RNA, Bacterial --- RNA, Archaeal --- Organelles --- mRNA Cleavage and Polyadenylation Factors --- RNA Stability --- RNA --- RNA-Binding Proteins --- Biochemical Phenomena --- Cytoplasmic Structures --- Cytoplasm --- Nucleic Acids --- Nucleoproteins --- Carrier Proteins --- Chemical Phenomena --- Intracellular Space --- Nucleic Acids, Nucleotides, and Nucleosides --- Proteins --- Phenomena and Processes --- Cellular Structures --- Chemicals and Drugs --- Amino Acids, Peptides, and Proteins --- Cells --- Anatomy --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Interactions ARN-protéines --- Régulation génétique --- Organelles, Cell --- Germs --- Microbes --- Gene expression --- Gene expression regulation --- Gene regulation --- Informational RNA --- Messenger ribonucleic acid --- mRNA --- Protein transcript --- Protein transcripts --- Template RNA --- Interactions, RNA-protein --- Protein-RNA interactions --- RNA-protein binding --- Regulation --- Prokaryotes --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Protein binding
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CRISPR-Cas is a recently discovered defense system which protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR-Cas immune systems has been identified in at least half of the available prokaryotic genomes. On-going biochemical and functional analyses have resulted in substantial insight into the functions and possible applications of these fascinating systems, although many secrets remain to be uncovered. In this book, experts summarize the state of the art of this exciting field.
Molecular biology. --- Molecular genetics. --- Bacterial genetics --- Biological Evolution --- Biology --- Immunity --- RNA --- Organisms --- Genetic Processes --- Immune System Phenomena --- Biological Science Disciplines --- Nucleic Acids --- Nucleic Acids, Nucleotides, and Nucleosides --- Genetic Phenomena --- Natural Science Disciplines --- Phenomena and Processes --- Chemicals and Drugs --- Disciplines and Occupations --- Evolution, Molecular --- Genetics --- Bacteria --- RNA, Archaeal --- Archaea --- RNA, Bacterial --- Adaptive Immunity --- Health & Biological Sciences --- Microbiology & Immunology --- Immunity. --- CRISPR (Genetics) --- Clustered Regularly Interspaced Short Palindromic Repeats (Genetics) --- Life sciences. --- Medical microbiology. --- Microbiology. --- Microbial genetics. --- Microbial genomics. --- Life Sciences. --- Microbial Genetics and Genomics. --- Medical Microbiology. --- Genomics --- Microbial genetics --- Microorganisms --- Microbiology --- Microbial biology --- Biosciences --- Sciences, Life --- Science --- Immunology
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