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Breast Neoplasms --- Immunohistochemistry --- Proto-Oncogene Proteins c-bcl-2 --- Tissue Fixation --- Glutathione --- metabolism --- methods

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In this book, scientists pioneering the field have compiled a series of focused chapters to highlight the relevance of the BCL‑2 family of proteins in apoptosis, physiology and disease. An important focus of this volume is considering the potential TH ERA PEUT IC benefits of targeting apoptosis pathways in the context of human disease. Readers interested in understanding how a cell handles stress and the consequences of dysregulation of this process for human disease will find this book very valuable. It attempts to describe a fascinating area of research where physiology and biomedicine converge at different levels, revealing a trip from the molecular regulation of apoptosis to the impact of this process to the physiology of a whole organism.

Apoptosis. --- Tumor proteins. --- Apoptosis --- Tumor proteins --- Bcl-2 protein family. --- Apoptosis Regulatory Proteins --- Cell Death --- Biological Science Disciplines --- Medicine --- Diseases --- Metabolic Phenomena --- Proto-Oncogene Proteins --- Health Occupations --- Phenomena and Processes --- Intracellular Signaling Peptides and Proteins --- Natural Science Disciplines --- Cell Physiological Processes --- Oncogene Proteins --- Disciplines and Occupations --- Cell Physiological Phenomena --- Proteins --- Neoplasm Proteins --- Peptides --- Pathology --- Proto-Oncogene Proteins c-bcl-2 --- Metabolism --- Neoplasms --- Physiology --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Biology --- Health & Biological Sciences --- Cytology --- Medicine. --- Human physiology. --- Molecular biology. --- Proteins. --- Biomedicine. --- Human Physiology. --- Protein Science. --- Biomedicine general. --- Molecular Medicine. --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology --- Human biology --- Medical sciences --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Physicians --- Tumor markers --- Cell death --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Composition --- Health Workforce --- Proteins . --- Biomedicine, general.