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"The book aims to provide the reader with a detailed description of protein structure and dynamics, combined with an in-depth discussion of the relationship between both these aspects and protein function. Adopting the structural-biophysical approach, we discuss these in relation to molecular interactions and thermodynamic changes that transpire in this highly complex system. There are several types of textbooks describing protein structure and function. Biochemistry textbooks emphasize the functional aspect of proteins and provide a rather general description of structure and structure-function relationship (SFR). Structural Biology textbooks provide an extensive description of protein structure and also refer to SFR with varying degrees of detail. However, energy-related aspects are often avoided. Molecular biophysics textbooks focus on molecular interactions and thermodynamic aspects of protein structure, but tend to lack detailed description of structural and dynamic aspects, as well as SFR. Our book refers to all of the aforementioned aspects and attempts to provide a unified view. Our energy-oriented approach is manifested throughout the book, whether we discuss structure, dynamics or specific functions of proteins. An extensive discussion of the energetics of protein structure is also given in a chapter dedicated to this topic"--Provided by publisher
Proteins --- Physical biochemistry --- Amino Acid Sequence --- Protein Conformation --- Structure-activity relationships --- physiology --- 577.122 --- 577.122 Protein metabolism --- Protein metabolism --- Amino Acid Sequences --- Sequence, Amino Acid --- Sequences, Amino Acid --- Protein Structure, Primary --- Primary Protein Structure --- Primary Protein Structures --- Protein Structures, Primary --- Structure, Primary Protein --- Structures, Primary Protein --- Peptides --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Biophysical chemistry --- Biochemistry --- Physical organic chemistry --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Proteins - Structure-activity relationships --- Proteins - physiology
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Concentrating on the aspects of protein function that are common to the majority of proteins, this collection of methods is brought together for reseachers who are without access to expensive equipment. Using these protocols researchers will be able to get information about the functional properties of any protein. A companion volume, "Protein Structure: A Practical Approach" also edited by Thomas Creighton, provides the methods necessary for the study of protein strucutre.
biochemie --- General biochemistry --- biochemistry --- proteïnen --- Relations structure-activité --- Affinity labeling --- Structure-activity relationships --- Affinity labeling. --- Structure-activity relationships. --- Relations structure-activité --- Biochemistry --- Proteins --- #WSCH:WBIO --- 577.122 --- 577.122 Protein metabolism --- Protein metabolism --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Protein affinity labeling --- Protein binding --- Technique --- Analysis --- physiology --- Basic Sciences. Chemistry --- Technique. --- Analysis. --- physiology. --- Proteins and Enzymes. --- Biochimie --- Protéines --- Analyse --- Electrophoresis. --- Molecular cloning. --- DNA. --- Physiology. --- Biochemistry - Technique --- Proteins - Structure-activity relationships --- Proteins - Affinity labeling --- Proteins - physiology --- DNA --- Genes --- Molecular structure-biological activity relationship
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Protein Conformation. --- Protein Denaturation. --- Protein Folding. --- Structure-Activity Relationship. --- Proteins --- Protéines --- Pathophysiology. --- Structure-activity relationships. --- Metabolism --- Disorders. --- Physiopathologie --- Pathophysiology --- Structure-activity relationships --- Disorders --- Protéines --- Protein Conformation --- Protein Denaturation --- Protein Folding --- Structure-Activity Relationship --- 577.122 --- 577.122 Protein metabolism --- Protein metabolism --- Relationship, Structure-Activity --- Relationships, Structure-Activity --- Structure Activity Relationship --- Structure-Activity Relationships --- Protein Folding, Globular --- Folding, Globular Protein --- Folding, Protein --- Foldings, Globular Protein --- Foldings, Protein --- Globular Protein Folding --- Globular Protein Foldings --- Protein Foldings --- Protein Foldings, Globular --- Proteostasis --- Protein Multimerization --- Intrinsically Disordered Proteins --- Denaturation, Protein --- Denaturations, Protein --- Protein Denaturations --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Metabolism&delete& --- Protein metabolism disorders --- Proteins - Pathophysiology --- Proteins - Structure-activity relationships --- Proteins - Metabolism - Disorders
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