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PROTEIN TRANSPORT --- BACTERIA --- PROTEIN TRANSPORT --- BACTERIA

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CELL BIOLOGY --- TRAINING COURSES --- PROTEIN SYNTHESIS --- PROTEIN TRANSPORT --- TRAINING COURSES --- CELL BIOLOGY --- TRAINING COURSES --- PROTEIN SYNTHESIS --- PROTEIN TRANSPORT --- TRAINING COURSES

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The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Trafficking in Neurons examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. The book is divided into seven sections that review mechanisms of protein transport, the role of protein trafficking in synapse formation, exo- and endocytosis, transport of receptors, tra

Neurons. --- Neurons - metabolism. --- Physiological transport. --- Protein Transport. --- Proteins. --- Proteins - Physiological transport. --- Proteins--Physiological transport, Neurons. Protein Transport. Neurons--metabolism. . --- Proteins --- Neurons --- Protein Transport --- Metabolism --- Cells --- Metabolic Phenomena --- Nervous System --- Biological Transport --- Phenomena and Processes --- Anatomy --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiological transport --- Anatomies --- Biologic Transport --- Transport, Biological --- Transport, Biologic --- Nervous Systems --- System, Nervous --- Systems, Nervous --- Metabolic Phenomenon --- Metabolic Process --- Metabolism Concepts --- Metabolism Phenomena --- Process, Metabolic --- Processes, Metabolic --- Anabolism --- Catabolism --- Metabolic Concepts --- Metabolic Processes --- Concept, Metabolic --- Concept, Metabolism --- Concepts, Metabolic --- Concepts, Metabolism --- Metabolic Concept --- Metabolism Concept --- Phenomena, Metabolic --- Phenomena, Metabolism --- Phenomenon, Metabolic --- Cell --- Protein Localization Processes, Cellular --- Protein Sorting --- Protein Targeting --- Protein Trafficking --- Gated Protein Transport --- Protein Translocation --- Transmembrane Protein Transport --- Vesicular Protein Transport --- Protein Sortings --- Protein Traffickings --- Protein Transport, Gated --- Protein Transport, Transmembrane --- Protein Transport, Vesicular --- Protein Transports --- Targeting, Protein --- Trafficking, Protein --- Traffickings, Protein --- Transmembrane Protein Transports --- Nerve Cells --- Cell, Nerve --- Cells, Nerve --- Nerve Cell --- Neuron --- Nerve cells --- Neurocytes --- Nervous system

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In the last few years, significant breakthroughs in transcription research expanded our appreciation for the complexity of molecular controls on gene expression in mammalian cells. In Transcription Factors: Methods and Protocols, experts in the field describe state-of-the-art approaches that investigators can use to probe critical mechanisms underlying transcription factor nuclear-cytoplasmic trafficking as well as to assess the functional impact of post-translational modifications on transcription factor function. The chapters are written by prominent scientists, many of whom developed these methods, and highlight protocols that focus on specific transcription factor family members with particular relevance to human disease. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and current, Transcription Factors: Methods and Protocols compiles the latest techniques for elucidating controls on transcription factor intracellular localization and activity, and consequently is unlike any other methods-based text on transcriptional regulation today. .

Transcription factors --- Transcription Factors --- Research --- Methodology --- Proteins --- Investigative Techniques --- Publication Formats --- Biological Transport --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Publication Characteristics --- Amino Acids, Peptides, and Proteins --- Metabolism --- Cytological Techniques --- Clinical Laboratory Techniques --- Laboratory Manuals --- Protein Transport --- Chemicals and Drugs --- Metabolic Phenomena --- Phenomena and Processes --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Metabolic Phenomenon --- Metabolic Process --- Metabolism Concepts --- Metabolism Phenomena --- Process, Metabolic --- Processes, Metabolic --- Anabolism --- Catabolism --- Metabolic Concepts --- Metabolic Processes --- Concept, Metabolic --- Concept, Metabolism --- Concepts, Metabolic --- Concepts, Metabolism --- Metabolic Concept --- Metabolism Concept --- Phenomena, Metabolic --- Phenomena, Metabolism --- Phenomenon, Metabolic --- Protein Localization Processes, Cellular --- Protein Sorting --- Protein Targeting --- Protein Trafficking --- Gated Protein Transport --- Protein Translocation --- Transmembrane Protein Transport --- Vesicular Protein Transport --- Protein Sortings --- Protein Traffickings --- Protein Transport, Gated --- Protein Transport, Transmembrane --- Protein Transport, Vesicular --- Protein Transports --- Targeting, Protein --- Trafficking, Protein --- Traffickings, Protein --- Transmembrane Protein Transports --- Diagnoses and Laboratory Examinations --- Diagnosis, Laboratory --- Laboratory Diagnosis --- Laboratory Examinations and Diagnoses --- Laboratory Techniques, Clinical --- Clinical Laboratory Technique --- Diagnoses, Laboratory --- Laboratory Diagnoses --- Laboratory Technique, Clinical --- Technique, Clinical Laboratory --- Techniques, Clinical Laboratory --- Transcription Factor --- Factor, Transcription --- Factors, Transcription --- Cytologic Technics --- Cytological Technic --- Cytological Technics --- Cytological Technique --- Technic, Cytological --- Technics, Cytological --- Technique, Cytological --- Techniques, Cytological --- Cytologic Technic --- Technic, Cytologic --- Technics, Cytologic --- Cell Biology --- Biologic Transport --- Transport, Biological --- Transport, Biologic --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Genetic transcription factors --- methods --- Cytology. --- Cell Biology. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Transcription factors - Research - Methodology

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"Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs."--

Proteins --- Structure. --- Intrinsically Disordered Proteins --- Carrier Proteins. --- Protein Conformation --- physiology. --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Binding Protein --- Binding Proteins --- Transport Proteins --- Protein, Binding --- Proteins, Binding --- Proteins, Carrier --- Proteins, Transport --- Protein Binding --- Receptors, Transferrin --- Carrier Protein --- Transport Protein --- Protein, Carrier --- Protein, Transport