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The analysis of protein function is a vital step in the characterization of any newly discovered protein. This new edition brings up to date the techniques used, and presents experimental procedures that can be performed in the average laboratory without recourse to highly specialised equipment. The protocols will be of use to both experienced and novice researchers and are accompanied by background information, hints and tips, and troubleshooting guides to ensure successful elucidation of protein function.

Proteins --- Protein binding --- Protéines --- physiology. --- Analysis. --- Research --- Methodology. --- Structure-activity relationships. --- Affinity labeling. --- Analyse --- Fixation --- Recherche --- Méthodologie --- Proteins. --- Protéines --- Méthodologie --- Physiology. --- LABORATORY MANUALS --- PROTEINS --- ESCHERICHIA COLI --- STRUCTURES --- DNA-BINDING PROTEINS --- GENE EXPRESSION --- PROTEIN FOLDING --- LIGAND BINDING --- PROTEIN SEQUENCE DETERMINATION --- CROSSLINKING --- AFFINITY LABELS --- IDENTIFICATION --- TECHNIQUES --- RECOMBINANT PROTEINS --- PRODUCTION --- ELECTROPHORESIS --- LIGANDS --- BINDING SITES --- LABELLING --- CHEMICAL STRUCTURE --- ANALYSIS

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Takes the novel approach to cover both the sequence and structure analysis of proteins in one volume and from an algorithmic perspective. It provides a comprehensive introduction to the analysis of protein sequence and structure analysis; takes an algorithmic approach, relying on computational methods rather than theoretical; provides an integrated presentation of theory, examples, exercises and applications; and includes coverage of both protein structure, and sequence, analysis. This book is accessible enough for biologists, yet rigorous enough for computer scientists and mathematicians.

Proteins --- Bioinformatics --- Protein Conformation --- Sequence Analysis, Protein --- Algorithms --- Computational Biology --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Amino Acid Sequence Analyses --- Amino Acid Sequence Determination --- Amino Acid Sequence Determinations --- Amino Acid Sequencing --- Peptide Sequence Determination --- Protein Sequencing --- Sequence Analyses, Amino Acid --- Sequence Analysis, Amino Acid --- Sequence Analysis, Peptide --- Sequence Determination, Amino Acid --- Sequence Determinations, Amino Acid --- Amino Acid Sequence Analysis --- Peptide Sequence Analysis --- Protein Sequence Analysis --- Sequence Determination, Protein --- Acid Sequencing, Amino --- Analyses, Peptide Sequence --- Analyses, Protein Sequence --- Analysis, Peptide Sequence --- Analysis, Protein Sequence --- Peptide Sequence Analyses --- Peptide Sequence Determinations --- Protein Sequence Analyses --- Protein Sequence Determination --- Protein Sequence Determinations --- Sequence Analyses, Peptide --- Sequence Analyses, Protein --- Sequence Determination, Peptide --- Sequence Determinations, Peptide --- Sequence Determinations, Protein --- Sequencing, Amino Acid --- Sequencing, Protein --- Molecular Sequence Annotation --- Algorithm --- Structure --- methods --- Data processing --- bioinformatics --- databanken --- databases --- aminozuursequenties --- amino acid sequences --- nucleotidenvolgordes --- nucleotide sequences --- chemische structuur --- chemical structure --- studieboeken --- textbooks --- eiwitten --- proteins --- Proteomics