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2012 (3)

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Book
Genome-wide prediction and analysis of protein-protein functional linkages in bacteria
Authors: ---
ISSN: 21934746 ISBN: 1461447054 1461447046 Year: 2012 Publisher: New York, NY : Springer,

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Abstract

Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus on protein-protein interaction predictions in bacteria. The authors will describe these methods and further highlight its use to predict various biological pathways and complexity of the cellular response to various environmental conditions. Topics include analysis of complex genome-scale protein-protein interaction networks, effects of reference genome selection on prediction accuracy, and genome sequence templates to predict protein function.


Book
Activity-based protein profiling
Authors: ---
ISSN: 03401022 ISBN: 3642283772 3642283780 9783642283772 Year: 2012 Volume: 324 Publisher: Berlin ; Heidelberg : Springer,

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M. B. Nodwell S. A. Sieber ABPP Methodology: Introduction and Overview J. Krysiak R. Breinbauer Activity-Based Protein Profiling for Natural Product Target Discovery P. P. Geurink L. M. Prely G. A. van der Marel R. Bischoff H. S. Overkleeft Photoaffinity Labeling in Activity-Based Protein Profiling W. P. Heal E. W. Tate Application of Activity-Based Protein Profiling to the Study of Microbial Pathogenesis Y.-G. Kim A. Saghatelian Functional Analysis of Protein Targets by Metabolomic Approaches.  .


Book
Microarrays in diagnostics and biomarker development
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ISBN: 3642282024 3642439764 3642282032 9786613697301 1280786914 Year: 2012 Publisher: Heidelberg, Germany : Springer,

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Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications. This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards “nanoarrays”, which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies.


Book
Antibody Arrays : Methods and Protocols
Authors: ---
ISBN: 1071610643 1071610635 Year: 2021 Publisher: New York, NY : Springer US : Imprint: Humana,

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This detailed book presents a technical overview and practical methodology of a variety of antibody array formats and technologies. As advantages and disadvantages of antibody array types are explored, the volume also delves into practical applications of antibody arrays pertaining to investigations of specific research topics and biological processes as well as guidance on the methods of processing, analysis, and storage of array data. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Antibody Arrays: Methods and Protocols aims to empower the reader with the information required to select the most appropriate array for their research application, with the technical knowledge to use and process the array, and with the knowledge to perform analysis that realizes the maximum benefit from the data generated.

Keywords

Immunoglobulins. --- Protein microarrays. --- Antibodies. --- Protein Array Analysis. --- Microarray Analysis. --- Microarrays, Protein --- Peptide biochips --- Peptide microarrays --- Protein biochips --- Biochips --- Immobilized proteins --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Microarray Analytical Devices --- Microarray Microchips --- Nanoarray Analytical Devices --- Analysis, Microarray --- Analytical Device, Microarray --- Analytical Device, Nanoarray --- Analytical Devices, Microarray --- Analytical Devices, Nanoarray --- Device, Microarray Analytical --- Device, Nanoarray Analytical --- Devices, Microarray Analytical --- Devices, Nanoarray Analytical --- Microarray Analytical Device --- Microarray Microchip --- Microchip, Microarray --- Microchips, Microarray --- Nanoarray Analytical Device --- Protein Array Assay --- Protein Arrays --- Protein Biochips --- Protein Microarray Analysis --- Protein Microarray Assay --- Protein Profiling Microarrays --- ProteinChip --- Protein Chips --- Protein Microarrays --- Protein Microchips --- Protein Profiling Chips --- Analyses, Protein Array --- Analyses, Protein Microarray --- Analysis, Protein Array --- Analysis, Protein Microarray --- Array Analyses, Protein --- Array Analysis, Protein --- Array Assay, Protein --- Array Assays, Protein --- Array, Protein --- Arrays, Protein --- Assay, Protein Array --- Assay, Protein Microarray --- Assays, Protein Array --- Assays, Protein Microarray --- Biochip, Protein --- Biochips, Protein --- Chip, Protein --- Chip, Protein Profiling --- Chips, Protein --- Chips, Protein Profiling --- Microarray Analyses, Protein --- Microarray Analysis, Protein --- Microarray Assay, Protein --- Microarray Assays, Protein --- Microarray, Protein --- Microarray, Protein Profiling --- Microarrays, Protein Profiling --- Microchip, Protein --- Microchips, Protein --- Profiling Chip, Protein --- Profiling Chips, Protein --- Profiling Microarray, Protein --- Profiling Microarrays, Protein --- Protein Array --- Protein Array Analyses --- Protein Array Assays --- Protein Biochip --- Protein Chip --- Protein Microarray --- Protein Microarray Analyses --- Protein Microarray Assays --- Protein Microchip --- Protein Profiling Chip --- Protein Profiling Microarray --- ProteinChips --- Protein Interaction Mapping --- Biology—Technique. --- Chemistry. --- Biological Techniques. --- Physical sciences

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