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Prostate cancer is the most frequently diagnosed non-cutaneous malignancy in men, and the second leading cause of male cancer-related mortality in the United States.  The last decade has seen unprecedented progress in the detection, prognosis, treatment and prevention of prostate cancer. These advances have been driven largely by an increased understanding of the underlying biochemistry, molecular biology and genetics of the disease. New cell and animal models have been developed that recapitulate the natural progression of prostate cancer. New technologies have allowed scientists to view in detail the genomic, proteomic, metabolomics and other –omic universe of cancer cells and tissues. This has resulted in a greater understanding of the pathophysiology of the disease.

Prostate -- Cancer -- Diet therapy. --- Prostate -- Cancer -- Genetic aspects. --- Prostate -- Cancer -- Molecular aspects. --- Prostate --- Exocrine Glands --- Cell Physiological Processes --- Neoplastic Processes --- Prostatic Diseases --- Genital Neoplasms, Male --- Genitalia, Male --- Prostatic Secretory Proteins --- Tumor Markers, Biological --- Kallikreins --- Antigens, Neoplasm --- Biochemical Processes --- Proteins --- Seminal Plasma Proteins --- Genital Diseases, Male --- Neoplasms --- Biochemical Phenomena --- Biological Markers --- Pathologic Processes --- Genitalia --- Serine Endopeptidases --- Tissues --- Cell Physiological Phenomena --- Chemical Processes --- Antigens --- Amino Acids, Peptides, and Proteins --- Urogenital Neoplasms --- Neoplasms by Site --- Phenomena and Processes --- Chemical Phenomena --- Male Urogenital Diseases --- Biological Factors --- Endopeptidases --- Urogenital System --- Anatomy --- Diseases --- Chemicals and Drugs --- Serine Proteases --- Pathological Conditions, Signs and Symptoms --- Peptide Hydrolases --- Hydrolases --- Enzymes --- Enzymes and Coenzymes --- Signal Transduction --- Prostatic Neoplasms --- Neoplasm Proteins --- Prostate-Specific Antigen --- Cell Transformation, Neoplastic --- Medicine --- Health & Biological Sciences --- Oncology --- Cancer --- Genetics. --- Cancer. --- Medicine. --- Cancer research. --- Medical biochemistry. --- Proteins. --- Cell biology. --- Systems biology. --- Biological systems. --- Biomedicine. --- Cancer Research. --- Medical Biochemistry. --- Cell Biology. --- Protein Science. --- Receptors. --- Biological Networks, Systems Biology. --- Biosystems --- Systems, Biological --- Biology --- System theory --- Systems biology --- Computational biology --- Bioinformatics --- Biological systems --- Molecular biology --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Pathology --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Physicians --- Philosophy --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Oncology. --- Biochemistry. --- Cytology. --- Cell receptors. --- Systems Biology. --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Binding sites (Biochemistry) --- Cell membranes --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Tumors --- Composition --- Proteins .