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Book
L'expérience dans l'innovation en santé : modes éphémères ou nouveau paradigme ?
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ISBN: 9781784059750 1784059757 Year: 2023 Publisher: Londres: ISTE,

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Abstract

Le recours à l'expérience des patients, usagers, professionnels de santé et autres parties prenantes pour innover et repenser les organisations et les systèmes de santé connait un véritable essor. Le déploiement de ces méthodes et pratiques innovantes nécessite toutefois la compréhension et la maîtrise de principes théoriques, ainsi qu'une expérimentation de ces dernières sur le terrain. L'expérience dans l'innovation en santé alterne exposés théoriques et études de cas/exemples pour présenter les notions clés de l'innovation en santé et de l'expérience des personnes qui sont au cœur des différents écosystèmes de soins et de santé. Il rassemble des perspectives, des points de vue divers et complémentaires permettant un éclairage nouveau sur la question de l'expérience en santé à travers le prisme de l'innovation. Il inclut de nombreuses ressources, idées et résultats pour toutes personnes, tous acteurs du soin souhaitant mettre en œuvre des approches innovantes plaçant l'expérience humaine au centre des écosystèmes de santé.


Book
Advances in Forensic Genetics
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Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The book has 25 articles about the status and new directions in forensic genetics. Approximately half of the articles are invited reviews, and the remaining articles deal with new forensic genetic methods. The articles cover aspects such as sampling DNA evidence at the scene of a crime; DNA transfer when handling evidence material and how to avoid DNA contamination of items, laboratory, etc.; identification of body fluids and tissues with RNA; forensic microbiome analysis with molecular biology methods as a supplement to the examination of human DNA; forensic DNA phenotyping for predicting visible traits such as eye, hair, and skin colour; new ancestry informative DNA markers for estimating ethnic origin; new genetic genealogy methods for identifying distant relatives that cannot be identified with conventional forensic DNA typing; sensitive DNA methods, including single-cell DNA analysis and other highly specialised and sensitive methods to examine ancient DNA from unidentified victims of war; forensic animal genetics; genetics of visible traits in dogs; statistical tools for interpreting forensic DNA analyses, including the most used IT tools for forensic STR-typing and DNA sequencing; haploid markers (Y-chromosome and mitochondria DNA); inference of ethnic origin; a comprehensive logical framework for the interpretation of forensic genetic DNA data; and an overview of the ethical aspects of modern forensic genetics.

Keywords

Research & information: general --- Biology, life sciences --- Genetics (non-medical) --- TaqMan SNP genotyping --- OpenArray™ system --- forensic DNA phenotyping --- forensic DNA typing --- animal forensics --- wildlife forensics --- cat STRs --- dog STRs --- cyt b --- COI --- biogeographic ancestry --- pigmentation --- skin color --- externally visible characteristics --- forensic genetics --- eye colour --- rs12913832 --- DNA phenotyping --- domestic dog (Canis familiaris) --- canine DNA phenotyping --- forensic --- proof of concept study --- evidence --- Y-STR --- mtDNA --- mitochondria --- bio-geographical ancestry --- massively parallel sequencing --- ancestry informative markers --- SNPs --- 1000 Genomes --- Human Origins SNP array --- FDP --- HIrisPlex-S --- DEPArray --- ancestry prediction --- phenotype prediction --- next-generation sequencing --- single-cell genomics --- single-cell sequencing --- mixture deconvolution --- low template DNA --- ltDNA --- probabilistic genotyping --- EuroForMix --- DNAStatistX --- STRmixTM --- DNA forensics --- DNA mixture --- mixture interpretation --- single-cell --- clustering algorithm --- number of contributors --- consensus profile --- cross-amplification --- microsatellites --- Strigiformes --- illegal trade --- kinship --- nocturnal raptors --- review --- body fluid --- organ --- tissue --- identification --- mRNA --- DNA methylation --- activity level --- massively parallel sequencing (MPS) --- next-generation sequencing (NGS) --- short tandem repeat (STR) --- sequence analysis --- software --- DNA transfer --- DNA persistence --- DNA prevalence --- DNA recovery --- activity level evaluation --- forensic science --- ethics --- ethics as lived practice --- decision-making --- genetic databasing --- forensic genealogy --- forensic epigenetics --- communication --- database --- SNP --- next generation sequencing --- hybridization capture --- bone --- transfer --- persistence --- activity --- Bayesian networks --- burglary --- CODIS --- touch DNA --- crime scene --- authorized --- sampling --- short tandem repeat --- forensic microbiology --- microbiome --- physical appearance --- human genome variation --- DNA-based prediction --- investigative leads --- forensic DNA intelligence --- forensic genomics --- degraded DNA --- mitochondrial DNA --- forensic DNA profiling --- ancient DNA --- human identification --- ancestry --- biostatistics --- clustering --- classification --- distance based --- likehood --- hypothesis tests --- DNA molecules --- decontamination --- cleaning strategies --- Romanov family --- next generation sequencing (NGS) --- heteroplasmy --- single nucleotide polymorphism (SNP) --- kinship analyses --- biological sexing --- DNA --- principles of interpretation --- investigative --- evaluative --- reporting --- LR --- propositions --- activity issues --- TaqMan SNP genotyping --- OpenArray™ system --- forensic DNA phenotyping --- forensic DNA typing --- animal forensics --- wildlife forensics --- cat STRs --- dog STRs --- cyt b --- COI --- biogeographic ancestry --- pigmentation --- skin color --- externally visible characteristics --- forensic genetics --- eye colour --- rs12913832 --- DNA phenotyping --- domestic dog (Canis familiaris) --- canine DNA phenotyping --- forensic --- proof of concept study --- evidence --- Y-STR --- mtDNA --- mitochondria --- bio-geographical ancestry --- massively parallel sequencing --- ancestry informative markers --- SNPs --- 1000 Genomes --- Human Origins SNP array --- FDP --- HIrisPlex-S --- DEPArray --- ancestry prediction --- phenotype prediction --- next-generation sequencing --- single-cell genomics --- single-cell sequencing --- mixture deconvolution --- low template DNA --- ltDNA --- probabilistic genotyping --- EuroForMix --- DNAStatistX --- STRmixTM --- DNA forensics --- DNA mixture --- mixture interpretation --- single-cell --- clustering algorithm --- number of contributors --- consensus profile --- cross-amplification --- microsatellites --- Strigiformes --- illegal trade --- kinship --- nocturnal raptors --- review --- body fluid --- organ --- tissue --- identification --- mRNA --- DNA methylation --- activity level --- massively parallel sequencing (MPS) --- next-generation sequencing (NGS) --- short tandem repeat (STR) --- sequence analysis --- software --- DNA transfer --- DNA persistence --- DNA prevalence --- DNA recovery --- activity level evaluation --- forensic science --- ethics --- ethics as lived practice --- decision-making --- genetic databasing --- forensic genealogy --- forensic epigenetics --- communication --- database --- SNP --- next generation sequencing --- hybridization capture --- bone --- transfer --- persistence --- activity --- Bayesian networks --- burglary --- CODIS --- touch DNA --- crime scene --- authorized --- sampling --- short tandem repeat --- forensic microbiology --- microbiome --- physical appearance --- human genome variation --- DNA-based prediction --- investigative leads --- forensic DNA intelligence --- forensic genomics --- degraded DNA --- mitochondrial DNA --- forensic DNA profiling --- ancient DNA --- human identification --- ancestry --- biostatistics --- clustering --- classification --- distance based --- likehood --- hypothesis tests --- DNA molecules --- decontamination --- cleaning strategies --- Romanov family --- next generation sequencing (NGS) --- heteroplasmy --- single nucleotide polymorphism (SNP) --- kinship analyses --- biological sexing --- DNA --- principles of interpretation --- investigative --- evaluative --- reporting --- LR --- propositions --- activity issues


Book
Advances in Forensic Genetics
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

Choose an application

Bookmark

Abstract

The book has 25 articles about the status and new directions in forensic genetics. Approximately half of the articles are invited reviews, and the remaining articles deal with new forensic genetic methods. The articles cover aspects such as sampling DNA evidence at the scene of a crime; DNA transfer when handling evidence material and how to avoid DNA contamination of items, laboratory, etc.; identification of body fluids and tissues with RNA; forensic microbiome analysis with molecular biology methods as a supplement to the examination of human DNA; forensic DNA phenotyping for predicting visible traits such as eye, hair, and skin colour; new ancestry informative DNA markers for estimating ethnic origin; new genetic genealogy methods for identifying distant relatives that cannot be identified with conventional forensic DNA typing; sensitive DNA methods, including single-cell DNA analysis and other highly specialised and sensitive methods to examine ancient DNA from unidentified victims of war; forensic animal genetics; genetics of visible traits in dogs; statistical tools for interpreting forensic DNA analyses, including the most used IT tools for forensic STR-typing and DNA sequencing; haploid markers (Y-chromosome and mitochondria DNA); inference of ethnic origin; a comprehensive logical framework for the interpretation of forensic genetic DNA data; and an overview of the ethical aspects of modern forensic genetics.

Keywords

TaqMan SNP genotyping --- OpenArray™ system --- forensic DNA phenotyping --- forensic DNA typing --- animal forensics --- wildlife forensics --- cat STRs --- dog STRs --- cyt b --- COI --- biogeographic ancestry --- pigmentation --- skin color --- externally visible characteristics --- forensic genetics --- eye colour --- rs12913832 --- DNA phenotyping --- domestic dog (Canis familiaris) --- canine DNA phenotyping --- forensic --- proof of concept study --- evidence --- Y-STR --- mtDNA --- mitochondria --- bio-geographical ancestry --- massively parallel sequencing --- ancestry informative markers --- SNPs --- 1000 Genomes --- Human Origins SNP array --- FDP --- HIrisPlex-S --- DEPArray --- ancestry prediction --- phenotype prediction --- next-generation sequencing --- single-cell genomics --- single-cell sequencing --- mixture deconvolution --- low template DNA --- ltDNA --- probabilistic genotyping --- EuroForMix --- DNAStatistX --- STRmixTM --- DNA forensics --- DNA mixture --- mixture interpretation --- single-cell --- clustering algorithm --- number of contributors --- consensus profile --- cross-amplification --- microsatellites --- Strigiformes --- illegal trade --- kinship --- nocturnal raptors --- review --- body fluid --- organ --- tissue --- identification --- mRNA --- DNA methylation --- activity level --- massively parallel sequencing (MPS) --- next-generation sequencing (NGS) --- short tandem repeat (STR) --- sequence analysis --- software --- DNA transfer --- DNA persistence --- DNA prevalence --- DNA recovery --- activity level evaluation --- forensic science --- ethics --- ethics as lived practice --- decision-making --- genetic databasing --- forensic genealogy --- forensic epigenetics --- communication --- database --- SNP --- next generation sequencing --- hybridization capture --- bone --- transfer --- persistence --- activity --- Bayesian networks --- burglary --- CODIS --- touch DNA --- crime scene --- authorized --- sampling --- short tandem repeat --- forensic microbiology --- microbiome --- physical appearance --- human genome variation --- DNA-based prediction --- investigative leads --- forensic DNA intelligence --- forensic genomics --- degraded DNA --- mitochondrial DNA --- forensic DNA profiling --- ancient DNA --- human identification --- ancestry --- biostatistics --- clustering --- classification --- distance based --- likehood --- hypothesis tests --- DNA molecules --- decontamination --- cleaning strategies --- Romanov family --- next generation sequencing (NGS) --- heteroplasmy --- single nucleotide polymorphism (SNP) --- kinship analyses --- biological sexing --- DNA --- principles of interpretation --- investigative --- evaluative --- reporting --- LR --- propositions --- activity issues

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