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The story of Depo-Provera joins the national struggle over the drug's FDA approval to the state legal issues raised by its contraceptive and criminal justice uses.Depo-Provera is known as an injectable hormonal birth control method, but few are familiar with its dark and complicated history. Depo-Provera was tested on women since the mid-1960s without their informed consent until it was FDA-approved in 1992, but never FDA-approved as chemical castration for male sex offenders.Contraceptive Risk is William Green's landmark study of Depo-Provera. Based on a fascinating combination of archival materials and interviews, the book is framed as three interconnected stories told by Judith Weisz, who chaired the FDA's Public Board of Inquiry on Depo-Provera, a scientific court; by Anne MacMurdo who brought a products liability suit against Upjohn, the drug's manufacturer, for the deleterious side effects she suffered from the drug's use; and by Roger Gauntlett, an Upjohn heir who, when he was convicted of sexual assault, refused to take a dose of his family's own medicine as a probation condition. Together these three stories of Depo-Provera's convoluted fifty year odyssey call for a paradigm shift in pharmaceutical drug development.Contraceptive Risk is a thoroughly researched and engrossing approach to the scientific, political and institutional forces involved in health law and policy, as well as the multifaceted politics of measuring risk.

Contraception. --- Women --- Contraceptives --- Birth control devices --- Contraceptive devices --- Medical instruments and apparatus --- Human females --- Wimmin --- Woman --- Womon --- Womyn --- Females --- Human beings --- Femininity --- Conception --- Birth control --- Reproductive rights --- Health risk assessment. --- Safety measures. --- Prevention --- Medroxyprogesterone --- Contraceptive drugs, Injectable --- Contraceptive Agents --- Medroxyprogesterone Acetate --- Pharmaceutical Research --- Risk Assessment --- Injectable contraceptives --- Injections --- Depo-Provera (Trademark) --- Hydroxymethylpregnenedione --- Hydroxymethylprogesterone --- Methylhydroxyprogesterone --- Provera (Trademark) --- Hydroxyprogesterone --- Progestational hormones, Synthetic --- Safety measures --- Health risk assessment --- adverse effects --- history --- ethics