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This new edition provides the most advanced research using bioprobes on the chemical control of 1) cell cycle and differentiation, 2) epigenetics, 3) apoptosis and autophagy, and 4) immune response. The “bioprobe”, first proposed in the first edition, has become an indispensable tool for chemical biology and has substantially assisted in the investigation of complex biochemical processes of cells. New areas of investigation such as stem cell research, epigenetic research, and autophagy research have rapidly advanced in the past 10 years. Including these new findings, this second edition supplies up-to-date information on the biochemical tools called bioprobes. Data on each bioprobe, such as chemical structure, origin, function, and references, are presented as one item in this volume. Readers will easily find useful information and will be able to determine the appropriate bioprobes to investigate cell functions. The information on bioprobes and their use in research makes this book a valuable source for researchers in diverse fields. Not only scientists in academia but also in the pharmaceutical industries will discover the most important information about small molecules useful for drug discovery.

Life sciences. --- Biotechnology. --- Organic chemistry. --- Biochemistry. --- Cell biology. --- Life Sciences. --- Cell Biology. --- Biochemistry, general. --- Organic Chemistry. --- Molecular probes. --- Bioprobes --- Probes, Molecular --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Organic chemistry --- Chemical engineering --- Genetic engineering --- Biosciences --- Sciences, Life --- Science --- Composition --- Molecular biology --- Affinity labeling --- Technique --- Cytology. --- Chemistry, Organic.

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The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume fami

Molecular probes. --- Diagnostic imaging. --- Imaging systems in medicine. --- Medical imaging systems --- Medical instruments and apparatus --- Clinical imaging --- Imaging, Diagnostic --- Medical diagnostic imaging --- Medical imaging --- Noninvasive medical imaging --- Diagnosis, Noninvasive --- Imaging systems in medicine --- Bioprobes --- Probes, Molecular --- Molecular biology --- Affinity labeling --- Technique

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This book discusses the latest research in the pathophysiology, diagnosis, and screening of diabetes and its management. It reviews novel technologies for early diagnosis and highlights the molecular mechanisms of microvascular and macrovascular complications of diabetes 2 mellitus. The book covers the applications of nanotechnology in diagnostics, monitoring, and treatment of diabetes mellitus. The chapter also presents the latest developments in differentiating pancreatic cells from PSCs and illustrates the challenges of their therapeutic application in treating diabetes. The book also explores the prospective medicinal plants comprising either plant extract or isolated bioactive phytoconstituents bearing anti-diabetic potential, which has been reported in several in vitro, in vivo, or clinical studies. It further examines the major mechanisms involved in cardiovascular complications among type 2 diabetes mellitus individuals and discusses the various pharmacological interventions and agents developed to delay cardiovascular events and thereby the quality and duration of the patients. Towards the end, the book summarizes the potential impact of ketogenic diets on diabetic patients, and the role of genetic vulnerability in diabetic nephropathy. As such, this book is a valuable source for students, researchers, and practitioners working in glucose metabolism, diabetes, and human health.

Human physiology. --- Metabolism. --- Molecular probes. --- Metabolism—Disorders. --- Human Physiology. --- Biological Sensors and Probes. --- Metabolic Disease. --- Bioprobes --- Probes, Molecular --- Molecular biology --- Affinity labeling --- Anabolism --- Catabolism --- Metabolism, Primary --- Primary metabolism --- Biochemistry --- Physiology --- Human biology --- Medical sciences --- Human body --- Technique --- Diabetes --- Research. --- Diabetes research

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This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.

Analytical biochemistry. --- Analytic biochemistry --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Biochemistry --- Analytical chemistry. --- Biochemistry. --- Biophysics. --- Molecular probes. --- Clinical medicine --- Analytical Chemistry. --- Analytical Biochemistry. --- Biological Chemistry. --- Bioanalysis and Bioimaging. --- Biological Sensors and Probes. --- Clinical Research. --- Research. --- Bioprobes --- Probes, Molecular --- Molecular biology --- Affinity labeling --- Biological physics --- Biology --- Medical sciences --- Physics --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry, Analytic --- Technique --- Composition

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Nuclear Medicine --- Molecular Imaging --- Nuclear medicine --- Molecular probes --- Diagnostic imaging --- Radioimmunoimaging --- Médecine nucléaire --- Sondes moléculaires --- Imagerie pour le diagnostic --- Immunoscintigraphie --- Periodicals. --- Periodicals --- Périodiques --- Nuclear Medicine. --- Molecular Imaging. --- Diagnostic imaging. --- Molecular probes. --- Nuclear medicine. --- Radioimmunoimaging. --- Immunoscintigraphy --- Atomic medicine --- Radioisotopes in medicine --- Bioprobes --- Probes, Molecular --- Clinical imaging --- Imaging, Diagnostic --- Medical diagnostic imaging --- Medical imaging --- Noninvasive medical imaging --- Imaging, Molecular --- Medicine, Atomic --- Medicine, Nuclear --- Radiology, Nuclear --- Atomic Medicine --- Nuclear Radiology --- nuclear medicine --- molecular imaging --- Immunodiagnosis --- Radioisotope scanning --- Medical radiology --- Radioactive tracers --- Radioactivity --- Molecular biology --- Affinity labeling --- Diagnosis, Noninvasive --- Imaging systems in medicine --- Nuclear Pharmacy --- Radiobiology --- Physiological effect --- Technique --- Physical methods for diagnosis --- Radiology, MRI, Ultrasonography & Medical Physics