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This Special Issue provides an update on the state of the art and current trends in polymeric drug-delivery systems specifically designed for improving drug bioavailability. The multiple contributions received further strengthen the role of polymers in modern drug delivery and targeting, illustrating the different approaches possible and unveiling what the future may bring.
Medicine --- Pharmaceutical industries --- cystic fibrosis --- Pseudomonas aeruginosa --- liposomes --- efflux pump inhibitor --- PABN --- aminoglycosides --- macrolides --- poloxamer --- thiourea --- thiolation --- mucoadhesion --- drug release --- in vivo analysis --- in vitro dissolution studies --- S-propargyl-cysteine --- poly(lactic acid) --- endogenous hydrogen sulfide --- water-in-oil-in-water --- rheumatoid arthritis --- chitosan --- drug delivery --- drug absorption --- intestinal assimilation --- oral bioavailability --- nanoemulsions --- micelles --- SEDDS --- zeta potential --- sustained release --- albumin nanoparticle --- MPT0B291 --- high-pressure homogenizer --- histone deacetylase --- calix[8]arenes --- silibinin --- inclusion complexes --- PEGylation --- cytotoxicity --- oromucosal films --- sodium alginate --- nanoparticle drug carriers --- digoxin --- zein --- heart failure --- polymer–liposome complexes --- Pluronic®-poly(acrylic acid) --- Pluronic®-poly(N,N-dimethylaminoethyl methacrylate) --- stimuli-responsive --- intelligent drug delivery systems --- liposome --- polymer --- long circulation --- polymer–lipid conjugates --- targeting --- stimulus-responsive --- antibody --- affinity --- cyclodextrin --- protein therapeutics --- sustained drug delivery --- Nitric oxide --- hydrogel --- wound dressing --- chronic wounds --- glycyrrhetinic acid --- Soluplus® --- solid dispersions --- anti-inflammatory --- biosafety --- bioavailability --- n/a --- polymer-liposome complexes --- polymer-lipid conjugates
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This reprint highlights high-quality original research and review papers that include innovative colloidal drug delivery systems and cutting-edge characterization techniques that significantly contribute to the area of nanomedicine. The results presented are of high interest for specialists from a broad spectrum of fields, including biomedical, pharmaceutical, industrial, and biotechnological spheres.
Technology: general issues --- Chemical engineering --- synthetic antimicrobial polymers --- assembled nanostructures --- surfaces and coatings --- antimicrobial properties --- folate-targeted nanoparticles --- BSA/alginate nanocarriers --- paclitaxel --- cellular uptake --- cell viability --- ciprofibrate --- drug delivery --- Rietveld method --- crystallography --- nanotechnology --- neuropathy --- polymeric nanoparticles --- preclinical investigation --- pharmacokinetics of pregabalin --- antinociceptive effect --- induced sleep --- polymer nanoparticles --- glioma/glioblastoma --- blood–brain barrier (BBB)/blood brain tumour barrier (BBTB) --- nanodiagnostics --- drug delivery and imaging --- nanocrystals --- surface modification --- chemotherapy --- cancer --- cyclosporine A --- ethoxylated fatty acid --- block copolymer --- polymeric micelles --- ocular --- nanoparticles --- natural and synthetic polymers --- drug delivery systems --- biocompatibility --- in vivo tests --- nicarbazin --- DNC --- glycyrrhizic acid --- PVP --- micelles --- coccidiosis --- Pluronic --- F127 --- drug delivery system --- active pharmaceutical ingredient --- antimicrobial activity
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This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.
Research & information: general --- film nanocomposite --- essential oil --- supercritical CO2 --- long-term package --- hybrid nanoparticles --- biocompatible polymer --- antimicrobial amphiphiles --- dynamic light scattering --- scanning electron microscopy --- cell viability from counting of colony-forming unities --- antimicrobial activity of nanoparticles --- Escherichia coli --- Staphylococcus aureus --- Candida albicans --- hydrogel --- polyvinyl alcohol --- aliphatic dicarboxylic acids --- sustained release --- linezolid --- equilibrium swelling ratio --- accumulative release --- thermogravimetric analysis --- gram-negative bacteria --- multidrug resistance --- polymer therapeutics --- colistin --- polymyxin B --- nanoliposomes --- MDR-Bacteria --- chitosan --- nanotechnologies --- plant extracts --- agro-food-wastes --- antimicrobial agents --- polymeric nanocarriers --- mixed polymeric micelles --- drug delivery --- antibiotics --- Pluronic F127 --- antimicrobial agent --- polymeric nanomaterial --- self-assembly --- antimicrobial peptide --- silver nanoparticle --- anti-biofilm --- wound healing --- bromelain --- nisin --- bioactivity --- biomedicine --- carrier --- n/a
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This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.
film nanocomposite --- essential oil --- supercritical CO2 --- long-term package --- hybrid nanoparticles --- biocompatible polymer --- antimicrobial amphiphiles --- dynamic light scattering --- scanning electron microscopy --- cell viability from counting of colony-forming unities --- antimicrobial activity of nanoparticles --- Escherichia coli --- Staphylococcus aureus --- Candida albicans --- hydrogel --- polyvinyl alcohol --- aliphatic dicarboxylic acids --- sustained release --- linezolid --- equilibrium swelling ratio --- accumulative release --- thermogravimetric analysis --- gram-negative bacteria --- multidrug resistance --- polymer therapeutics --- colistin --- polymyxin B --- nanoliposomes --- MDR-Bacteria --- chitosan --- nanotechnologies --- plant extracts --- agro-food-wastes --- antimicrobial agents --- polymeric nanocarriers --- mixed polymeric micelles --- drug delivery --- antibiotics --- Pluronic F127 --- antimicrobial agent --- polymeric nanomaterial --- self-assembly --- antimicrobial peptide --- silver nanoparticle --- anti-biofilm --- wound healing --- bromelain --- nisin --- bioactivity --- biomedicine --- carrier --- n/a
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This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.
Research & information: general --- film nanocomposite --- essential oil --- supercritical CO2 --- long-term package --- hybrid nanoparticles --- biocompatible polymer --- antimicrobial amphiphiles --- dynamic light scattering --- scanning electron microscopy --- cell viability from counting of colony-forming unities --- antimicrobial activity of nanoparticles --- Escherichia coli --- Staphylococcus aureus --- Candida albicans --- hydrogel --- polyvinyl alcohol --- aliphatic dicarboxylic acids --- sustained release --- linezolid --- equilibrium swelling ratio --- accumulative release --- thermogravimetric analysis --- gram-negative bacteria --- multidrug resistance --- polymer therapeutics --- colistin --- polymyxin B --- nanoliposomes --- MDR-Bacteria --- chitosan --- nanotechnologies --- plant extracts --- agro-food-wastes --- antimicrobial agents --- polymeric nanocarriers --- mixed polymeric micelles --- drug delivery --- antibiotics --- Pluronic F127 --- antimicrobial agent --- polymeric nanomaterial --- self-assembly --- antimicrobial peptide --- silver nanoparticle --- anti-biofilm --- wound healing --- bromelain --- nisin --- bioactivity --- biomedicine --- carrier
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Mucoadhesive polymers are widely used in the design of dosage forms for transmucosal drug delivery to the eye, respiratory, gastrointestinal and reproductive tracts. These routes of drug administration offer a number of advantages including improved drug bioavailability, reduced frequency of administration, and the avoidance for the use of injections.
chitosan --- maltodextrin --- Caco-2 cells --- alkyl lactate --- mucosal drug delivery --- thermogelling polymers --- buccal mucosa drug delivery --- drug delivery --- triple co-culture model --- oral lichen planus --- mucoadhesive polymers --- cyclodextrins --- paediatric --- mucoadhesion --- nanoparticles --- pectin --- furosemide --- oral lyophilisates --- films --- wound healing --- pluronic f127 --- interpolymer complexes --- transmucosal permeations --- Alzheimer’s disease --- biocompatibility --- poly (vinylpyrrolidone) --- mucosal membranes --- scanning electron microscopic images --- pioglitazone --- hydrogel --- resuspendibility --- thermoresponsive polymers --- mucoadhesive microspheres --- trimethyl chitosan --- Candida albicans --- xanthan gum --- omeprazole --- texture profile analysis --- acrylated chitosan --- mucoadhesive --- clotrimazole --- clobetasol --- Carbopol® --- hydroxypropyl cellulose --- electrospinning --- chitosan derivatives --- in vitro permeability --- l-arginine --- resveratrol --- cytotoxicity --- retention --- thiolated hyaluronic acid --- Carbopol --- mucoadhesive polymer --- rheology --- Eudragit® E PO --- detachment force --- chitosan-catechol --- controlled release --- PLGA-PEG --- liposphere --- gellan gum --- storage and loss moduli --- thiolated chitosan --- interpolyelectrolyte complex --- poly(2-ethyl-2-oxazoline)
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Based on five Special Issues in Coatings, this e-book contains a series of 15 articles demonstrating actual perspectives and new trends in advanced coatings in buildings. Innovative materials and multiperformance solutions provide a basis, contributing also to the better protection of buildings’ surfaces during the service life, and the users’ wellbeing.
History of engineering & technology --- geopolymer --- metakaolin --- titanium oxide --- physical and mechanical properties --- polystyrene --- DOPA --- polydopamine --- antifouling --- polyethylene glycol --- Pluronic --- QCM-D --- coating --- building materials --- bacterial growth --- proliferation --- biofilm --- antibacterial --- hydrophobic --- photocatalytic --- sonochemistry --- mortar --- polydimethylsiloxane --- phenylmethylsilicone oil --- viscosity --- additive amount --- leach --- particle size --- distribution characteristics --- contaminated particle --- porcelain insulator --- adhesion simulation model --- cellulose --- aerogel --- thermal insulation --- building envelope --- silica --- ceramic coating --- fly ash --- anti-fouling --- slagging --- boiler --- energy efficiency --- biofilms --- DEMM --- DEME --- PMMA --- polymer brush coating --- polysaccharide --- protein --- lipid --- nucleic acid --- Raman spectroscopy --- AgNPs --- antibacterial coatings --- polyetheretherketone films --- tollens method --- acrylic resin --- bio-filler --- cone calorimeter --- heat release rate --- intumescent coating --- steel --- green roofs --- biological coatings --- hydraulic performance --- thermal performance --- sustainable construction certification --- LEED --- BREEAM --- CASBEE --- BEAM --- ESGB --- glass waste --- copper oxide --- antibacterial surfaces --- hydrophobic products --- silicon-based compounds --- claddings --- durability --- moisture transport properties --- recycled and reused materials --- drainage --- dead load --- protective coatings --- air-purifying coatings --- anti-fouling coatings --- ultra-low biofouling coatings
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This book is a collection of papers published in the Special Issue of Pharmaceutics, entitled "Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules". A drug release profile is a consequential factor for nanoparticle application, directly related to drug stability and therapeutic results, as well as formulation development. Pharmaceutical particulates of different sizes and shapes (e.g., liposomes, oil-in-water emulsions, polymeric nano- and microspheres, metallic nanoparticles (NPs) such as gold, silver and iron oxide crystals, and core-shell hybrid NPs) offer many diagnostic and therapeutic applications. Membranes are also extensively utilized in many applications. They are especially beneficial to the distribution of macromolecular drugs and biopharmaceutical drugs (peptides, proteins, antibodies, oligonucleotides, plasmids, and viruses) with physicochemical and pharmacokinetic vulnerability. The delivery of drugs and bioactive molecules using particulates and membranes has gained a great deal of attention for various applications, such as the treatment of secondary infections, cancer treatment, skin regeneration, orthopaedic applications, and antimicrobial drug delivery. In addition, several production techniques have been utilized for the fabrication of particulates and membranes in the last decade, which include lyophilisation, micro-emulsion, nano-spray dryer, nano-electrospinning, slip casting and 3D printers. Therefore, pharmaceutical particulates and membranes possess excellent prospects to deliver drugs and bioactive molecules with the potential to improve new delivery strategies like sustained and controlled release.
alginate gelispheres --- textural analysis --- crosslinked matrices --- PLGA discs --- prolonged release --- powder flow properties --- microfluidics --- coculture --- HER2 --- polystyrene µPs --- biofunctionalization --- coaxial electrospraying --- polymeric nanoparticles --- spreading angle --- process-property-performance relationship --- nanoemulsion --- mixture design --- aqueous humor --- antimicrobial activity --- sustained release pellets --- double coating layer --- loxoprofen --- citric acid --- pharmacokinetic studies --- biomimetic magnetite --- drug delivery --- magnetic hyperthermia --- magnetite --- MamC --- nanoparticles stability --- pharmaceutical particulates --- membranes --- drug delivery systems --- bio-imaging --- bioactive molecules --- composite --- N-hydroxyphthalimide --- carbon dots --- polymer gels --- antitumoral activity --- wound dressing --- polymeric membrane --- nanoparticles --- curcumin --- alginate --- pluronic F68 --- drug skin permeation --- Franz cells --- tape stripping --- wound infection --- biofilm --- pseudomonas aeruginosa --- antimicrobial delivery --- polyvinylpyrrolidone --- nanofibers --- red blood cells membrane --- arsenic trioxide --- sodium alginate nanoparticles --- reduce toxicity --- anti-tumor --- pediatric drug delivery --- tuberculosis --- reconstitutable dry suspension --- isoniazid --- polymer-lipid --- microparticulate --- direct emulsification --- n/a
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Based on five Special Issues in Coatings, this e-book contains a series of 15 articles demonstrating actual perspectives and new trends in advanced coatings in buildings. Innovative materials and multiperformance solutions provide a basis, contributing also to the better protection of buildings’ surfaces during the service life, and the users’ wellbeing.
geopolymer --- metakaolin --- titanium oxide --- physical and mechanical properties --- polystyrene --- DOPA --- polydopamine --- antifouling --- polyethylene glycol --- Pluronic --- QCM-D --- coating --- building materials --- bacterial growth --- proliferation --- biofilm --- antibacterial --- hydrophobic --- photocatalytic --- sonochemistry --- mortar --- polydimethylsiloxane --- phenylmethylsilicone oil --- viscosity --- additive amount --- leach --- particle size --- distribution characteristics --- contaminated particle --- porcelain insulator --- adhesion simulation model --- cellulose --- aerogel --- thermal insulation --- building envelope --- silica --- ceramic coating --- fly ash --- anti-fouling --- slagging --- boiler --- energy efficiency --- biofilms --- DEMM --- DEME --- PMMA --- polymer brush coating --- polysaccharide --- protein --- lipid --- nucleic acid --- Raman spectroscopy --- AgNPs --- antibacterial coatings --- polyetheretherketone films --- tollens method --- acrylic resin --- bio-filler --- cone calorimeter --- heat release rate --- intumescent coating --- steel --- green roofs --- biological coatings --- hydraulic performance --- thermal performance --- sustainable construction certification --- LEED --- BREEAM --- CASBEE --- BEAM --- ESGB --- glass waste --- copper oxide --- antibacterial surfaces --- hydrophobic products --- silicon-based compounds --- claddings --- durability --- moisture transport properties --- recycled and reused materials --- drainage --- dead load --- protective coatings --- air-purifying coatings --- anti-fouling coatings --- ultra-low biofouling coatings
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Based on five Special Issues in Coatings, this e-book contains a series of 15 articles demonstrating actual perspectives and new trends in advanced coatings in buildings. Innovative materials and multiperformance solutions provide a basis, contributing also to the better protection of buildings’ surfaces during the service life, and the users’ wellbeing.
History of engineering & technology --- geopolymer --- metakaolin --- titanium oxide --- physical and mechanical properties --- polystyrene --- DOPA --- polydopamine --- antifouling --- polyethylene glycol --- Pluronic --- QCM-D --- coating --- building materials --- bacterial growth --- proliferation --- biofilm --- antibacterial --- hydrophobic --- photocatalytic --- sonochemistry --- mortar --- polydimethylsiloxane --- phenylmethylsilicone oil --- viscosity --- additive amount --- leach --- particle size --- distribution characteristics --- contaminated particle --- porcelain insulator --- adhesion simulation model --- cellulose --- aerogel --- thermal insulation --- building envelope --- silica --- ceramic coating --- fly ash --- anti-fouling --- slagging --- boiler --- energy efficiency --- biofilms --- DEMM --- DEME --- PMMA --- polymer brush coating --- polysaccharide --- protein --- lipid --- nucleic acid --- Raman spectroscopy --- AgNPs --- antibacterial coatings --- polyetheretherketone films --- tollens method --- acrylic resin --- bio-filler --- cone calorimeter --- heat release rate --- intumescent coating --- steel --- green roofs --- biological coatings --- hydraulic performance --- thermal performance --- sustainable construction certification --- LEED --- BREEAM --- CASBEE --- BEAM --- ESGB --- glass waste --- copper oxide --- antibacterial surfaces --- hydrophobic products --- silicon-based compounds --- claddings --- durability --- moisture transport properties --- recycled and reused materials --- drainage --- dead load --- protective coatings --- air-purifying coatings --- anti-fouling coatings --- ultra-low biofouling coatings
Listing 1 - 10 of 17 | << page >> |
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