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Waldenström macroglobulinemia (WM) is a rare lymphoplasmacytic lymphoma characterized by the presence of an immunoglobulin M (IgM) monoclonal protein. WM is a chronic, indolent disease, which can remain undiagnosed for years. A better understanding of the role of signaling pathways in the development of the disease and the identification of clinical and genetic markers have driven the development of targeted therapeutic strategies, improving overall survival. In this resource, the authors distill current knowledge on the pathophysiology, epidemiology and etiology of WM and discuss how the disease may present, how it is diagnosed and whentreatment should be initiated. They also provide an overview of current approaches to treatment as well as ongoing and planned research directions. It contains a wealth of information for those working in the field and will be of particular value to specialist nurses and trainees in the fields of hematology, oncology, gerontology, pathology and neurology.

Hematology. --- Plasma cell diseases. --- Plasma cell disorders --- Plasma cell dyscrasias --- Connective tissues --- Immunologic diseases --- Haematology --- Internal medicine --- Blood --- Diseases

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This volume provides a comprehensive, state-of-the art review on the field of diagnostic hematopathology as it is applied to patients with plasma cell neoplasms. The book places particular emphasis on immunophenotypic data – immunohistochemistry and flow cytometry – as well as cytogenetics, and discusses how these ancillary data can predict prognosis and chemotherapeutic response. It also provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.  Written by experts in their fields, Plasma Cell Neoplasms serves as a very useful resource for physicians and researchers interested in plasma cell myeloma diagnosis, therapy, and research.    .

Oncology. --- Plasma cell diseases -- Treatment. --- Pathology --- Medicine --- Health & Biological Sciences --- Plasma cell diseases --- Treatment. --- Plasma cell disorders --- Plasma cell dyscrasias --- Tumors --- Connective tissues --- Immunologic diseases --- Diseases --- Pathology. --- Oncology  . --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive

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This book provides an overview of our current understanding of the pathogenesis of the plasma cell neoplasms and comprehensively updates the reader on the laboratory techniques used in the diagnosis and prognostication of these malignancies as well as for monitoring response to therapy. Plasma Cell Neoplasms: Pathogenesis, Diagnosis and Laboratory Evaluation will be of great value to those medical professionals directly involved in the evaluation and diagnosis of clinical materials from patients with plasma cell neoplasms, including surgical pathologists, hematopathologists, and clinical pathologists.

Medicine. --- Pathology. --- Medicine & Public Health. --- Multiple myeloma. --- Plasma cell diseases. --- Plasmacytoma. --- Plasma cell disorders --- Plasma cell dyscrasias --- Kahler's disease --- Plasma cell myeloma --- B cells --- Monoclonal gammopathies --- Plasmacytoma --- Lymphomas --- Connective tissues --- Immunologic diseases --- Tumors --- Diseases --- Disease (Pathology) --- Medical sciences --- Medicine --- Medicine, Preventive