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Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants that are clinically important. This book is also focused on the challenges of diagnostic interpretation of NGS results in a clinical setting.

Genomics. --- Medical genetics. --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Genome research --- Genomes --- Molecular genetics --- Genetic aspects --- Research --- Community Health Planning --- Public Health --- Biostatistics --- Health Education --- Health Promotion --- Community Health Systems --- Population-Based Planning --- Community Health Plannings --- Community Health System --- Health Planning, Community --- Health Plannings, Community --- Health System, Community --- Health Systems, Community --- Planning, Community Health --- Planning, Population-Based --- Plannings, Community Health --- Plannings, Population-Based --- Population Based Planning --- Population-Based Plannings --- System, Community Health --- Systems, Community Health --- Promotional Items --- Health Campaigns --- Promotion of Health --- Wellness Programs --- Campaign, Health --- Campaigns, Health --- Health Campaign --- Health Promotions --- Item, Promotional --- Items, Promotional --- Program, Wellness --- Programs, Wellness --- Promotion, Health --- Promotional Item --- Promotions, Health --- Wellness Program --- Preventive Health Services --- Preventive Medicine --- Education, Community Health --- Health Education, Community --- Community Health Education --- Education, Health --- Health --- Biological Statistics --- Biological Statistic --- Statistic, Biological --- Statistics, Biological --- Community Health --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Community --- Health, Public --- Education, Public Health Professional --- education

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This salient reference grounds readers in the theoretical basis and day-to-day practice of community-based health care programs, and their potential as a transformative force in public health. Centering around concepts of self-determination, empowerment, and inclusiveness, the book details the roles of physicians, research, and residents in the transition to self-directed initiatives and greater community control. Community-focused interventions and methods, starting with genuine dialogue between practitioners and residents, are discussed as keys to understanding local voice and worldview, and recognizing residents as active participants and not simply targets of service delivery. And coverage pays careful attention to training issues, including how clinicians can become involved in community-based care without neglecting individual patient needs.   Among the topics covered are:          Narrative medicine in the context of community-based practice.          Qualitative and participatory action research.           Health committees as a community-based strategy.          Dialogue, world entry, and community-based intervention.           Politics of knowledge in community-based work.          Training physicians with communities. Dimensions of Community-Based Projects in Health Care challenges sociologists, social workers, and public health administrators to look beyond traditional biomedical concepts of care and naturalistic methods of research, and toward more democratic programs, planning, and policy. The partnerships described in these pages reflect a deep commitment to patients’ lives, and to the future of public health.

Community health services --- Social service. --- Medicine. --- Psychology, clinical. --- Quality of Life --- Social Work and Community Development. --- Health Promotion and Disease Prevention. --- Health Psychology. --- Quality of Life Research. --- Life, Quality of --- Economic history --- Human ecology --- Life --- Social history --- Basic needs --- Human comfort --- Social accounting --- Work-life balance --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Benevolent institutions --- Philanthropy --- Relief stations (for the poor) --- Social service agencies --- Social welfare --- Social work --- Human services --- Research. --- Community Health Services. --- Community Health Planning. --- Primary Health Care. --- United States. --- Primary Healthcare --- Primary Care --- Care, Primary --- Care, Primary Health --- Health Care, Primary --- Healthcare, Primary --- Community Health Systems --- Population-Based Planning --- Community Health Plannings --- Community Health System --- Health Planning, Community --- Health Plannings, Community --- Health System, Community --- Health Systems, Community --- Planning, Community Health --- Planning, Population-Based --- Plannings, Community Health --- Plannings, Population-Based --- Population Based Planning --- Population-Based Plannings --- System, Community Health --- Systems, Community Health --- Community Healthcare --- Health Services, Community --- Services, Community Health --- Community Health Care --- Care, Community Health --- Community Health Service --- Community Healthcares --- Health Care, Community --- Health Service, Community --- Healthcare, Community --- Healthcares, Community --- Service, Community Health --- Public Health Administration --- Social Work --- Community Health Planning --- Health Workforce --- Health promotion. --- Health psychology. --- Quality of life. --- Health psychology --- Health psychology, Clinical --- Psychology, Clinical health --- Psychology, Health --- Salutogenesis --- Clinical psychology --- Medicine and psychology --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education

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Social Welfare --- Age Groups --- Internationality --- Vital Statistics --- Regional Health Planning --- Demography --- Persons --- Health Planning --- Sociology --- Data Collection --- Social Sciences --- Health Care Economics and Organizations --- Epidemiologic Methods --- Information Science --- Named Groups --- Epidemiologic Measurements --- Population Characteristics --- Anthropology, Education, Sociology and Social Phenomena --- Health Care --- Investigative Techniques --- Public Health --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Environment and Public Health --- Community Health Planning --- International Cooperation --- Mortality --- Child Welfare --- Adolescent --- Child --- Infant --- Medicine --- Health & Biological Sciences --- Pediatrics --- Infants --- Children --- Minors --- Adolescents --- Adolescents, Female --- Adolescents, Male --- Teenagers --- Teens --- Adolescence --- Youth --- Adolescent, Female --- Adolescent, Male --- Female Adolescent --- Female Adolescents --- Male Adolescent --- Male Adolescents --- Teen --- Teenager --- Youths --- Adolescent Welfare --- Welfare, Adolescent --- Welfare, Child --- Child Health --- Child Health Services --- Social Work --- Age Specific Death Rate --- Age-Specific Death Rate --- Case Fatality Rate --- Decline, Mortality --- Determinants, Mortality --- Differential Mortality --- Excess Mortality --- Mortality Decline --- Mortality Determinants --- Mortality Rate --- Mortality, Differential --- Mortality, Excess --- CFR Case Fatality Rate --- Crude Death Rate --- Crude Mortality Rate --- Death Rate --- Age-Specific Death Rates --- Case Fatality Rates --- Crude Death Rates --- Crude Mortality Rates --- Death Rate, Age-Specific --- Death Rate, Crude --- Death Rates --- Determinant, Mortality --- Differential Mortalities --- Excess Mortalities --- Mortalities --- Mortality Declines --- Mortality Determinant --- Mortality Rate, Crude --- Mortality Rates --- Rate, Age-Specific Death --- Rate, Case Fatality --- Rate, Crude Death --- Rate, Crude Mortality --- Rate, Death --- Rate, Mortality --- Rates, Case Fatality --- Disease --- Treaties --- Foreign Aid --- Aid, Foreign --- Cooperation, International --- Treaty --- Community Health Systems --- Population-Based Planning --- Community Health Plannings --- Community Health System --- Health Planning, Community --- Health Plannings, Community --- Health System, Community --- Health Systems, Community --- Planning, Community Health --- Planning, Population-Based --- Plannings, Community Health --- Plannings, Population-Based --- Population Based Planning --- Population-Based Plannings --- System, Community Health --- Systems, Community Health --- Community Health --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Community --- Health, Public --- Preventive Medicine --- Education, Public Health Professional --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Population Heterogeneity --- Population Statistics --- Characteristic, Population --- Characteristics, Population --- Heterogeneity, Population --- Population Characteristic --- Statistics, Population --- Measurements, Epidemiologic --- Epidemiologic Measurement --- Measurement, Epidemiologic --- Information Sciences --- Science, Information --- Sciences, Information --- Epidemiologic Method --- Epidemiological Methods --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- Epidemiology --- Healthcare Economics and Organizations --- Health Care Economics --- Health Economics --- Healthcare Economics --- Care Economic, Health --- Economic, Health --- Economic, Health Care --- Economic, Healthcare --- Economics, Health Care --- Health Care Economic --- Health Economic --- Healthcare Economic --- Science, Social --- Sciences, Social --- Social Science --- Data Collection Methods --- Dual Data Collection --- Collection Method, Data --- Collection Methods, Data --- Collection, Data --- Collection, Dual Data --- Data Collection Method --- Method, Data Collection --- Methods, Data Collection --- Medical History Taking --- Empirical Research --- General Social Development and Population --- PL93-641 --- Public Law 93-641 --- Health and Welfare Planning --- National Health Planning and Resources Development Act of 1974 --- Planning, Health and Welfare --- State Health Planning, United States --- Planning, Health --- Public Law 93 641 --- Planning Techniques --- Person --- Accounting, Demographic --- Analyses, Demographic --- Analyses, Multiregional --- Analysis, Period --- Brass Technic --- Brass Technique --- Demographers --- Demographic Accounting --- Demographic Analysis --- Demographic Factor --- Demographic Factors --- Demographic Impact --- Demographic Impacts --- Demographic Survey --- Demographic Surveys --- Demographic and Health Surveys --- Demographics --- Demography, Historical --- Demography, Prehistoric --- Factor, Demographic --- Factors, Demographic --- Family Reconstitution --- Historical Demography --- Impact, Demographic --- Impacts, Demographic --- Multiregional Analysis --- Period Analysis --- Population Spatial Distribution --- Prehistoric Demography --- Reverse Survival Method --- Stable Population Method --- Survey, Demographic --- Surveys, Demographic --- Demographer --- Demographic --- Demographic and Health Survey --- Population Distribution --- Analyses, Period --- Analysis, Demographic --- Analysis, Multiregional --- Demographic Analyses --- Demographies, Historical --- Demographies, Prehistoric --- Distribution, Population --- Distribution, Population Spatial --- Distributions, Population --- Distributions, Population Spatial --- Family Reconstitutions --- Historical Demographies --- Method, Reverse Survival --- Method, Stable Population --- Methods, Reverse Survival --- Methods, Stable Population --- Multiregional Analyses --- Period Analyses --- Population Distributions --- Population Methods, Stable --- Population Spatial Distributions --- Prehistoric Demographies --- Reconstitution, Family --- Reconstitutions, Family --- Reverse Survival Methods --- Spatial Distribution, Population --- Spatial Distributions, Population --- Stable Population Methods --- Technic, Brass --- Technique, Brass --- Review, Appropriateness --- Annual Implementation Plans --- Appropriateness Review --- Areawide Planning --- Comprehensive Health Planning --- Annual Implementation Plan --- Appropriateness Reviews --- Health Planning, Comprehensive --- Health Planning, Regional --- Implementation Plan, Annual --- Implementation Plans, Annual --- Plan, Annual Implementation --- Planning, Areawide --- Planning, Comprehensive Health --- Planning, Regional Health --- Plans, Annual Implementation --- Reviews, Appropriateness --- Registration of Vital Statistics --- Registration, Vital Statistics --- Statistics, Vital --- Vital Statistics Registration --- Registrations, Vital Statistics --- Vital Statistics Registrations --- Globalization --- International Aspects --- International Perspectives --- International Relations --- Multinational Aspects --- Multinational Perspectives --- Aspect, International --- Aspect, Multinational --- Aspects, International --- Aspects, Multinational --- International Aspect --- International Perspective --- Multinational Aspect --- Multinational Perspective --- Perspective, International --- Perspective, Multinational --- Perspectives, International --- Perspectives, Multinational --- Relations, International --- International Law --- Age Group --- Group, Age --- Groups, Age --- Community Services --- Services, Community --- Community Service --- Service, Community --- Welfare, Social --- Public Assistance --- mortality --- methods