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Interracial marriage --- Interracial marriage --- World War, 1939-1945 --- Mariage interracial --- 2ème guerre mondiale --- Law and legislation --- Deportations from Italy. --- Déportés italiens --- Pirani Cardosi, Clara, --- Correspondence. --- Auschwitz (Concentration camp)

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Microfluidics and lab-on-a-chip have, in recent years, come to the forefront in diagnostics and detection. At point-of-care, in the emergency room, and at the hospital bed or GP clinic, lab-on-a-chip offers the potential to rapidly detect time-critical and life-threatening diseases such as sepsis and bacterial meningitis. Furthermore, portable and user-friendly diagnostic platforms can enable disease diagnostics and detection in resource-poor settings where centralised laboratory facilities may not be available. At point-of-use, microfluidics and lab-on-chip can be applied in the field to rapidly identify plant pathogens, thus reducing the need for damaging broad spectrum pesticides while also reducing food losses. Microfluidics can also be applied to the continuous monitoring of water quality and can support policy-makers and protection agencies in protecting the environment. Perhaps most excitingly, microfluidics also offers the potential to enable entirely new diagnostic tests that cannot be implemented using conventional laboratory tools. Examples of microfluidics at the frontier of new medical diagnostic tests include early detection of cancers through circulating tumour cells (CTCs) and highly sensitive genetic tests using droplet-based digital PCR.This Special Issue on “Advances in Microfluidics Technology for Diagnostics and Detection” aims to gather outstanding research and to carry out comprehensive coverage of all aspects related to microfluidics in diagnostics and detection.

Medicine --- biosensors --- LoaD platforms --- microfluidics --- centrifugal microfluidics --- PoC devices --- SARS-CoV-2 --- COVID-19 --- nano-qPCR --- ultra-sensitive --- viral RNA --- viral load --- detection --- LabDisk --- vector-borne diseases --- malaria --- arboviruses --- insecticide resistances --- mosquito monitoring --- SAW --- Pirani --- compact --- wireless --- vacuum --- sensing --- digital droplet polymerase chain reaction (ddPCR) --- multiplexing --- centrifugal step emulsification --- droplet stability --- droplet fluorescence evaluation --- nanoparticle --- lipoplex --- polyplex --- raspberry pi --- siRNA --- python --- n/a

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Children’s bone growth is continuous, and remodelling is always extensive. Growth proceeds from a vulnerable part of the bone, the growth plate. In remodelling, old bone tissue is gradually replaced by new tissue. Many bone disorders arise from the changes that occur in a growing child’s musculoskeletal system, and these disorders can positively or negatively impact bone development. Other bone disorders may be inherited or occur in childhood for unknown reasons.Bone disorders in children can result from factors that affect people of all ages, including injury, infection (osteomyelitis), cancer, and metabolic diseases. Causes of bone disorders can involve the gradual misalignment of bones and stress on growth plates during growth. Congenital deformities such as clubfoot or developmental dysplasia of the hip can lead to important alterations of bone development, causing severe dysfunction. Certain rare connective tissue disorders can also affect the bones, such as Marfan syndrome, osteogenesis imperfecta, and osteochondrodysplasias.Many specialists are involved in the management of bone development disorders in children and adolescents, such as neurosurgeons, plastic surgeons, general surgeons, ORL surgeons, maxillofacial surgeons, orthopaedics, radiologists, and pediatric intensive care physicians.The aim of this Special Issue is to present the latest research on the etiology, physiopathology, diagnosis and screening, management, and rehabilitation related to bone development and disease in infants, focusing on congenital, developmental, post-traumatic, and post-infective disorders.

Medicine --- pediatric --- growing age --- complex regional pain syndrome --- reflex sympathetic dystrophy --- multidisciplinary --- physical therapy --- cognitive behavioral therapy --- drugs --- pharmacological treatment --- occupational therapy --- supracondylar humerus fracture --- humerus fracture --- upper limb fracture --- fracture laterality --- handedness --- pediatric orthopedics --- developmental dysplasia of the hip --- DDH --- treatment --- conservative --- bracing --- dynamic splint --- static splint --- Legg–Calvé–Perthes disease --- Herring lateral pillar classification --- Stulberg classification --- Waldenström stage --- duration --- chronological age --- skeletal maturity --- Cervical Vertebral Maturation --- douple diapering --- neonatal hip --- DDH prevention --- hip positioning --- hip extension --- hip adduction --- clubfoot --- CTEV --- sport --- sport practice --- sport activity level --- young athletes --- ponseti method --- bone tumors --- Ewing’s sarcoma --- infants --- children --- composite prosthesis --- Pirani score --- Dimeglio score --- interobserver reliability --- congenital talipes equinovarus --- hemophilia --- prophylaxis --- high-impact sports --- physical activity --- psychological wellness --- trauma --- lockdown --- pandemic --- SARS-Co-V-2 --- n/a --- Legg-Calvé-Perthes disease --- Waldenström stage --- Ewing's sarcoma

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Children’s bone growth is continuous, and remodelling is always extensive. Growth proceeds from a vulnerable part of the bone, the growth plate. In remodelling, old bone tissue is gradually replaced by new tissue. Many bone disorders arise from the changes that occur in a growing child’s musculoskeletal system, and these disorders can positively or negatively impact bone development. Other bone disorders may be inherited or occur in childhood for unknown reasons.Bone disorders in children can result from factors that affect people of all ages, including injury, infection (osteomyelitis), cancer, and metabolic diseases. Causes of bone disorders can involve the gradual misalignment of bones and stress on growth plates during growth. Congenital deformities such as clubfoot or developmental dysplasia of the hip can lead to important alterations of bone development, causing severe dysfunction. Certain rare connective tissue disorders can also affect the bones, such as Marfan syndrome, osteogenesis imperfecta, and osteochondrodysplasias.Many specialists are involved in the management of bone development disorders in children and adolescents, such as neurosurgeons, plastic surgeons, general surgeons, ORL surgeons, maxillofacial surgeons, orthopaedics, radiologists, and pediatric intensive care physicians.The aim of this Special Issue is to present the latest research on the etiology, physiopathology, diagnosis and screening, management, and rehabilitation related to bone development and disease in infants, focusing on congenital, developmental, post-traumatic, and post-infective disorders.

pediatric --- growing age --- complex regional pain syndrome --- reflex sympathetic dystrophy --- multidisciplinary --- physical therapy --- cognitive behavioral therapy --- drugs --- pharmacological treatment --- occupational therapy --- supracondylar humerus fracture --- humerus fracture --- upper limb fracture --- fracture laterality --- handedness --- pediatric orthopedics --- developmental dysplasia of the hip --- DDH --- treatment --- conservative --- bracing --- dynamic splint --- static splint --- Legg–Calvé–Perthes disease --- Herring lateral pillar classification --- Stulberg classification --- Waldenström stage --- duration --- chronological age --- skeletal maturity --- Cervical Vertebral Maturation --- douple diapering --- neonatal hip --- DDH prevention --- hip positioning --- hip extension --- hip adduction --- clubfoot --- CTEV --- sport --- sport practice --- sport activity level --- young athletes --- ponseti method --- bone tumors --- Ewing’s sarcoma --- infants --- children --- composite prosthesis --- Pirani score --- Dimeglio score --- interobserver reliability --- congenital talipes equinovarus --- hemophilia --- prophylaxis --- high-impact sports --- physical activity --- psychological wellness --- trauma --- lockdown --- pandemic --- SARS-Co-V-2 --- n/a --- Legg-Calvé-Perthes disease --- Waldenström stage --- Ewing's sarcoma