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MOTOR CORTEX --- PYRAMIDAL TRACTS --- ELECTRIC STIMULATION --- MAGNETICS --- PHYSICAL STIMULATION --- EFFERENT PATHWAYS --- SPINAL CORD --- MOTOR NEURONS --- MOTOR CORTEX --- PYRAMIDAL TRACTS --- ELECTRIC STIMULATION --- MAGNETICS --- PHYSICAL STIMULATION --- EFFERENT PATHWAYS --- SPINAL CORD --- MOTOR NEURONS

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PHRENIC NERVE --- RESPIRATION DISORDERS --- ELECTRIC STIMULATION --- PHYSICAL STIMULATION --- RESPIRATORY THERAPY --- RESPIRATION, ARTIFICIAL --- PHRENIC NERVE --- PHYSIOPATHOLOGY --- PHYSIOLOGY --- PHRENIC NERVE --- RESPIRATION DISORDERS --- ELECTRIC STIMULATION --- PHYSICAL STIMULATION --- RESPIRATORY THERAPY --- RESPIRATION, ARTIFICIAL --- PHRENIC NERVE --- PHYSIOPATHOLOGY --- PHYSIOLOGY

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The present book recapitulates the articles published within the Special Issue "Cartilage Repair and Regeneration: Focus on Multi-Disciplinary Strategies", Applied Sciences, MDPI, dealing with the innovative multi-disciplinary therapeutic approaches for musculoskeletal diseases. In particular the published studies space from advanced 3D bioprinting technology to obtain a scaffold with different zonal cell densities, and biphasic scaffold (ChondroMimetic) construction, pass through the comparison of different techniques for cartilage regeneration such as of mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) and histopathological features of osteochondral units, and end with the considerations regarding development of bioreactors able to mimic the biomechanical load on chondrocytes in vitro, giving some interesting insights in this specific scientific field.

Medicine --- Pharmacology --- mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach --- mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach

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The present book recapitulates the articles published within the Special Issue "Cartilage Repair and Regeneration: Focus on Multi-Disciplinary Strategies", Applied Sciences, MDPI, dealing with the innovative multi-disciplinary therapeutic approaches for musculoskeletal diseases. In particular the published studies space from advanced 3D bioprinting technology to obtain a scaffold with different zonal cell densities, and biphasic scaffold (ChondroMimetic) construction, pass through the comparison of different techniques for cartilage regeneration such as of mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) and histopathological features of osteochondral units, and end with the considerations regarding development of bioreactors able to mimic the biomechanical load on chondrocytes in vitro, giving some interesting insights in this specific scientific field.

mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach

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This book and its companion volume describe state-of-the-art advances in techniques associated with implantable neural prosthetic devices and their applications. They offer researchers, engineers, clinicians, students and any specialists in this field a deeper understanding of the neural prosthetic techniques currently available for a wide range of biomedical applications. In part two of this two-volume sequence, Implantable Neural Prostheses: Techniques and Engineering Approaches, the focus is on general techniques, platforms, and engineering approaches in research and development. Coverage includes biocompatibility, electrode materials and testing, electrochemical techniques for neural stimulation applications, thin-film electrode arrays, hermetic and thin-film packaging, and microelectronics for recording, stimulation and wireless telemetry. Also discussed is the design process in the development of medical devices.

Implants, Artificial. --- Nervous system -- Surgery. --- Prosthesis. --- Prosthesis --- Implants, Artificial --- Nervous system --- Electric Stimulation --- Electrodes, Implanted --- Deep Brain Stimulation --- Prosthesis Design --- Prostheses and Implants --- Nervous System --- Anatomy --- Equipment and Supplies --- Electrodes --- Physical Stimulation --- Equipment Design --- Electric Stimulation Therapy --- Surgical Procedures, Operative --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Electrical Equipment and Supplies --- Investigative Techniques --- Therapeutics --- Biomedical Engineering --- Neurology --- Prosthesis & Artificial Organs --- Medicine --- Health & Biological Sciences --- Surgery & Anesthesiology --- Surgery --- Surgery. --- Nerves --- Neurosurgery --- Artificial implants --- Implants, Surgical --- Surgical implants --- Prostheses --- Prosthetics --- Engineering. --- Neurosciences. --- Biophysics. --- Biological physics. --- Medical physics. --- Radiation. --- Biomedical engineering. --- Biomaterials. --- Biomedical Engineering. --- Medical and Radiation Physics. --- Biophysics and Biological Physics. --- Biomedical materials --- Moulage in medicine --- Surgery, Plastic --- Artificial organs --- Biomedical Engineering and Bioengineering. --- Biological and Medical Physics, Biophysics. --- Health physics --- Health radiation physics --- Medical radiation physics --- Radiotherapy physics --- Radiation therapy physics --- Biophysics --- Physics --- Clinical engineering --- Medical engineering --- Bioengineering --- Engineering --- Biocompatible materials --- Biomaterials --- Medical materials --- Biomedical engineering --- Materials --- Biocompatibility --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Bioartificial materials --- Hemocompatible materials --- Biological physics --- Biology --- Radiology --- Biomaterials (Biomedical materials)