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Bisphosphonates are commonly prescribed to inhibit bone loss in patients with osteoporosis, as well as osteopenia, cancer, and Paget's disease of the bone. Recently, scientific literature has addressed a possible relationship between bisphosphonates and osteonecrosis of the jaw (ONJ). It is important to note that though the risks for developing ONJ are much higher for cancer patients on intravenous bisphosphonate therapy (used to reduce bone pain), the occurrence of ONJ also in patients treated with oral BF for osteoporosis has been also highlighted, though rarely. On the basis of the large use of BF, of their pharmacokinetics, of the systemic and local risk factors, physicians prescribing them and dental surgeons should be well informed on the various aspects of the problem. Aim of this volume is to offer an update on the current status of prevention, and on the current conservative and surgical treatments. The multidisciplinary approach will be very much appreciated by GP’s, the different specialists using bisphosphonates and by dental surgeons.

Bones -- Necrosis. --- Diphosphonates -- Physiological effect. --- Jaws -- Necrosis. --- Temporomandibular joint --- Organophosphorus Compounds --- Organic Chemicals --- Chemicals and Drugs --- Diphosphonates --- Medicine --- Dentistry --- Health & Biological Sciences --- Diseases by Body Region --- Oral Surgery --- TMJ Diseases --- Diseases --- Jaws --- Bones --- Necrosis. --- Physiological effect. --- Biphosphonates --- Bisphosphonates --- Osteonecrosis --- Phossy jaw --- Dentistry. --- Pharmacy. --- Medicine. --- General practice (Medicine). --- Radiology. --- Hematology. --- Oral surgery. --- Maxillofacial surgery. --- Medicine & Public Health. --- Oral and Maxillofacial Surgery. --- General Practice / Family Medicine. --- Imaging / Radiology. --- Phosphonates --- Surgery. --- Family medicine. --- Radiology, Medical. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Chemistry --- Drugs --- Materia medica --- Pharmacology --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Haematology --- Internal medicine --- Blood --- Dental surgery --- Odontology --- Surgery, Dental --- Oral medicine --- Teeth --- Surgery, Primitive --- Oral surgery --- Surgery, Oral --- Oral surgeons --- Radiological physics --- Physics --- Radiation