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Biomolecules --- Mass spectrometry. --- Analysis. --- MASS SPECTROMETRY --- PROTEINS --- PEPTIDES --- OLIGOSACCHARIDES --- LIPIDS --- GLYCOLIPIDS --- OLIGONUCLEOTIDES --- PEPTIDE LIBRARY --- ANALYSIS

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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Antigeen-determinanten --- Antigen determinants --- Antigenic determinant groups --- Antigenic determinants --- Determinanten [Antigeen-] --- Determinants [Antigenic ] --- Déterminants antigéniques --- Epitopes --- Epitypes --- Expressie [Gen-] --- Expression génétique --- Gen-expressie --- Gene expression --- Genes--Expression --- Fusion genique --- Proteines --- Expression genique --- Analyse --- Gene fusion. --- Proteins. --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Proteins --- Gene expression. --- Analysis. --- Fixation protéique --- Gene mapping --- Genetic mapping --- Genetisch materiaal [In kaart brengen van ] --- Genome --- Genome mapping --- Genomen --- Genomes --- Génomes --- In kaart brengen van genetisch materiaal --- Linkage mapping (Genetics) --- Mapping [Gene ] --- Protein binding --- Proteïnenbinding --- Représentation génétique --- Genes --- Fusion, Gene --- Expression --- Cytofysiologie --- Cytophysiologie --- Fysiologie [Cyto] --- Physiologie [Cyto] --- Antigenic determinants. --- Cytology --- Cell physiology --- Analysis --- Purification --- Reactivity --- Genetic regulation --- Microbial mutation --- Transduction --- Translocation (Genetics) --- Proteines - Analyse --- Cell lineage --- Chimeric proteins --- Gene fusion --- Membrane proteins --- Protein hybridization --- Peptide library --- Antibodies --- Antigens

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Shmuel Cabilly presents in Combinatorial Peptide Library Protocols a collection of new and unique techniques for the construction and use of peptide libraries. These powerful methods-often detailed here by their pioneers-include protocols for the chemical synthesis of peptide libraries, for constructing peptide libraries that are displayed on the surface of filamentous phage or bacteria, and for the rapid screening of these libraries for molecules with biospecific properties. Additional methods permit identifying specific enzyme substrates, investigating the recognition spectra of various binding proteins, epitope mapping, and identifying mimotopes. Combinatorial Peptide Library Protocols offers novice and experienced investigators alike the ability to select molecules from a randomized pool having specific biological activities. Its state-of-the-art techniques, combined with clear step-by-step instructions, make this book an essential tool in the selection of peptides suitable for drug development.

Protein binding --- Combinatorial chemistry --- Peptides --- Synthesis --- Protein Binding --- Peptide Library --- Molecular Sequence Data --- Gene Library --- Amino Acids, Peptides, and Proteins --- Metabolism --- Amino Acid Sequence --- Biochemical Processes --- Documentation --- Genetic Structures --- Chemical Processes --- Chemicals and Drugs --- Information Services --- Metabolic Phenomena --- Molecular Structure --- Biochemical Phenomena --- Phenomena and Processes --- Information Science --- Genetic Phenomena --- Chemical Phenomena --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Combinatorial chemistry. --- Protein binding. --- Synthesis. --- Life sciences. --- Biochemistry. --- Life Sciences. --- Biochemistry, general. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Biosciences --- Sciences, Life --- Science --- Composition --- Binding, Protein --- Biochemistry --- Allosteric proteins --- Radioligand assay --- Combinatorial organic synthesis --- Combinatorial synthesis (Organic chemistry) --- High-throughput organic synthesis --- High-throughput synthesis (Organic chemistry) --- Multiple parallel synthesis (Organic chemistry) --- Organic compounds --- Pharmaceutical chemistry --- Biochips --- Peptide synthesis --- Peptides - Synthesis

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Combinatorial Chemistry encompasses both the design of compounds for specific pharmacological use and the screening of molecules in high throughput automated tests to find active agents with specific functions.*Analytical techniques*Direct sorting split and pool combinatorial synthesis*Linkers and their applications*Microwave assisted synthesis*Oligosaccharide chemistry*Peptide Synthesis and Screening*Polymer assisted approaches*Small molecule and heterocycle synthesis

Chemistry, Pharmaceutical. --- Combinatorial chemistry techniques. --- Combinatorial chemistry. --- Molecular biology. --- Molecular pharmacology. --- Combinatorial Chemistry Techniques --- Chemistry, Pharmaceutical --- Pharmacology --- Chemistry --- Technology, Pharmaceutical --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biological Science Disciplines --- Natural Science Disciplines --- Disciplines and Occupations --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Pharmaceutic Technology --- Pharmaceutical Technology --- Pharmacy Technology --- Technology, Pharmaceutic --- Technology, Pharmacy --- Drug Industry --- Pharmacologies --- Pharmaceutical Preparations --- Chemistry, Pharmaceutic --- Pharmaceutic Chemistry --- Pharmaceutical Chemistry --- Medicinal Chemistry --- Chemistry, Medicinal --- Chemistry Technic, Combinatorial --- Chemistry Technics, Combinatorial --- Chemistry Technique, Combinatorial --- Combinatorial Chemistry Technic --- Combinatorial Chemistry Technics --- Combinatorial Chemistry Technique --- Technic, Combinatorial Chemistry --- Technics, Combinatorial Chemistry --- Technique, Combinatorial Chemistry --- Chemistry Techniques, Combinatorial --- Techniques, Combinatorial Chemistry --- Gene Library --- Peptide Library --- Oligonucleotide Array Sequence Analysis --- High-Throughput Screening Assays --- Click Chemistry --- pharmacology --- Organic compounds --- Synthesis.