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This book is a review on the evolution of cell-based microarrays and an update to the author's earlier book Methods in Molecular Biology: Cell-Based Microarrays. Since their development in 2001, cell-based microarrays have advanced significantly to include expression arrays, short interfering RNA arrays and antibody arrays. The surface used to coat the glass slides has also been significantly improved to allow non-adherent cells to bind to the arrays.

Protein microarrays --- Life sciences --- Statistical methods. --- Biology. --- Biosciences --- Sciences, Life --- Science --- Microarrays, Protein --- Peptide biochips --- Peptide microarrays --- Protein biochips --- Biochips --- Immobilized proteins --- Cytology. --- DNA microarrays. --- Human genetics. --- Cell Biology. --- Microarrays. --- Human Genetics. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- DNA biochips --- Microarrays, DNA --- Immobilized nucleic acids --- Cell biology.

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New Antibody Microarray Tube for Cellular Localization and Signaling Pathways describes a new integrated protein biochip system including protein localization, biocomputing and signaling pathways. In the post-genome era, proteomics study for direct analysis of a group of proteins becomes more and more important. Identification of its location often provides crucial information for understanding the function or regulation of a given protein in biological pathways. The book discusses a new microarray tube with incorporation of nuclear and cytoplasmic protein purification and biocomputing technologies, intended for setting-up signaling pathways and making new discoveries. The book is intended for researchers in the fields of medicine, biology, electronics, pharmacy, computer science and mathematics. Lin Wang is an associate professor at the Biomedical Engineering Center, Beijing University of Posts and Telecommunications, China. .

Bioinformatics. --- Protein microarrays. --- Proteomics. --- Microarrays, Protein --- Peptide biochips --- Peptide microarrays --- Protein biochips --- Engineering. --- Biomedical engineering. --- Biomedical Engineering. --- Molecular biology --- Proteins --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Data processing --- Biochips --- Immobilized proteins --- Biomedical Engineering and Bioengineering. --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine

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Frontiers in Biochip Technology Dr. Wan-Li Xing and Dr. Jing Cheng Frontiers in Biochip Technology serves as an essential collection of new research in the field of biochip technology. This comprehensive collection covers emerging technologies and cutting –edge research in the field of biochip technology, with all chapters written by the international stars of this evolving field. Key topics and current trends in biochip technology covered include: -microarray technology and its applications - microfluidics - drug discovery - detection technology - lab-on-chip technology and bioinformatics. Frontiers in Biochip Technology is an important volume for all biotechnologists, bioengineers, genetic engineers, pharmacological researchers, and general bench researchers who want to be up-to-date on the latest advances in the rapidly growing field of biochip technology. The Editors: Dr. Wan-Li Xing, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China Dr. Xing is a Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, and also serves as the Executive Deputy Director at NERCBBT, CapitalBio Corporation, a world-leader in biochip research. Dr. Xing has published widely and obtained many patents and applications. Dr. Jing Cheng, Tsinghua University School of Medicine, National Engineering Research Center for Beijing Biochip Technology (NERCBBT), and CapitalBio Corporation, Beijing, China Dr. Jing Cheng is the Cheung Kong Professor at Medical Systems Biology Research Center, Tsinghua University School of Medicine, the Director of NERCBBT and CEO & CTO of CapitalBio. Dr. Cheng developed the world’s first system of laboratory-on-a-chip in 1998; this work was featured in the front-cover story of the June 1998 issue of Nature Biotechnology and cited as the breakthrough of the year by Science in the same year. He has been awarded Nanogen’s most prestigious award Nano Grant, Distinguished Achievement Award for Overseas Chinese Scholars Returned, China’s Science & Technology Award for Outstanding Youth, and Qiushi Technology Transfer Award for Outstanding Youth. Dr. Cheng has published over 90 peer-reviewed papers. In addition, he has obtained over 60 European and U.S. patents and applications.

Biochips --- Genomics --- Bioinformatics --- DNA microarrays. --- Protein microarrays. --- Microfluidics. --- Research. --- Fluidics --- Nanofluids --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Genome research --- Genomes --- Molecular genetics --- Bioreactors --- Molecular computers --- Combinatorial chemistry --- DNA biochips --- Microarrays, DNA --- Immobilized nucleic acids --- Microarrays, Protein --- Peptide biochips --- Peptide microarrays --- Protein biochips --- Immobilized proteins --- Data processing --- Research --- Biomedical engineering. --- Biotechnology. --- Human genetics. --- Toxicology. --- Biomedical Engineering and Bioengineering. --- Human Genetics. --- Pharmacology/Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Chemical engineering --- Genetic engineering --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Toxicology --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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This detailed book presents a technical overview and practical methodology of a variety of antibody array formats and technologies. As advantages and disadvantages of antibody array types are explored, the volume also delves into practical applications of antibody arrays pertaining to investigations of specific research topics and biological processes as well as guidance on the methods of processing, analysis, and storage of array data. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Antibody Arrays: Methods and Protocols aims to empower the reader with the information required to select the most appropriate array for their research application, with the technical knowledge to use and process the array, and with the knowledge to perform analysis that realizes the maximum benefit from the data generated.

Immunoglobulins. --- Protein microarrays. --- Antibodies. --- Protein Array Analysis. --- Microarray Analysis. --- Microarrays, Protein --- Peptide biochips --- Peptide microarrays --- Protein biochips --- Biochips --- Immobilized proteins --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Microarray Analytical Devices --- Microarray Microchips --- Nanoarray Analytical Devices --- Analysis, Microarray --- Analytical Device, Microarray --- Analytical Device, Nanoarray --- Analytical Devices, Microarray --- Analytical Devices, Nanoarray --- Device, Microarray Analytical --- Device, Nanoarray Analytical --- Devices, Microarray Analytical --- Devices, Nanoarray Analytical --- Microarray Analytical Device --- Microarray Microchip --- Microchip, Microarray --- Microchips, Microarray --- Nanoarray Analytical Device --- Protein Array Assay --- Protein Arrays --- Protein Biochips --- Protein Microarray Analysis --- Protein Microarray Assay --- Protein Profiling Microarrays --- ProteinChip --- Protein Chips --- Protein Microarrays --- Protein Microchips --- Protein Profiling Chips --- Analyses, Protein Array --- Analyses, Protein Microarray --- Analysis, Protein Array --- Analysis, Protein Microarray --- Array Analyses, Protein --- Array Analysis, Protein --- Array Assay, Protein --- Array Assays, Protein --- Array, Protein --- Arrays, Protein --- Assay, Protein Array --- Assay, Protein Microarray --- Assays, Protein Array --- Assays, Protein Microarray --- Biochip, Protein --- Biochips, Protein --- Chip, Protein --- Chip, Protein Profiling --- Chips, Protein --- Chips, Protein Profiling --- Microarray Analyses, Protein --- Microarray Analysis, Protein --- Microarray Assay, Protein --- Microarray Assays, Protein --- Microarray, Protein --- Microarray, Protein Profiling --- Microarrays, Protein Profiling --- Microchip, Protein --- Microchips, Protein --- Profiling Chip, Protein --- Profiling Chips, Protein --- Profiling Microarray, Protein --- Profiling Microarrays, Protein --- Protein Array --- Protein Array Analyses --- Protein Array Assays --- Protein Biochip --- Protein Chip --- Protein Microarray --- Protein Microarray Analyses --- Protein Microarray Assays --- Protein Microchip --- Protein Profiling Chip --- Protein Profiling Microarray --- ProteinChips --- Protein Interaction Mapping --- Biology—Technique. --- Chemistry. --- Biological Techniques. --- Physical sciences