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With the advances in nanomaterials and nanofabrication, surface-enhanced Raman spectroscopy (SERS) has been extensively developed and applied in the trace detection of various analytes in either a simple or a complicated sample matrix. This includes, but is not limited to, the detection of antibiotic residues in animal-producing meat products, detection of pathogenic bacteria in human body fluid, and detection of heavy metal contamination of water. This book, consisting two review articles and five research articles, covers the most recent progress and advancement in the development and application of various nanomaterials in SERS trace detection. In this book, a broad range of topics is covered, from the synthesis of novel nanomaterials that can provide improved reproducibility of SERS signals to the development of new application protocols that can facilitate the reliable detection of trace amounts of analytes without interfered by the sample matrices significantly. This book is a useful source for both new and advanced researchers in the field of SERS and its application.

SERS --- Ag NPs --- coffee ring --- pesticide detection --- Surface-enhanced Raman spectroscopy (SERS) --- wire mesh --- steel mesh --- SERS platform --- Escherichia coli --- Bacillus subtilis --- biomolecule --- surface enhanced Raman spectroscopy (SERS) --- nanomaterial --- analysis --- identification --- biology --- chemometrics --- resistance --- biosensing --- rapid detection --- Ag nanowires --- tartrazine --- large yellow croaker --- surface-enhanced Raman spectroscopy --- transformer aging --- concentration detection --- circulating tumor cells (CTC) --- prostate cancer (PC3) --- cervical carcinoma (HeLa) --- label-free detection

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Public law. Constitutional law --- Political systems --- European law --- Representative government and representation --- Ministerial responsibility --- International and municipal law --- Gouvernement représentatif --- Responsabilité ministérielle --- Droit international et droit interne --- -Ministerial responsibility --- -328.3456094 --- Pc3 --- Countersignature (Constitutional law) --- Responsibility, Ministerial --- Cabinet officers --- Cabinet system --- Legislative bodies --- Monarchy --- Political science --- Parliamentary government --- Political representation --- Representation --- Self-government --- Constitutional history --- Constitutional law --- Democracy --- Elections --- Republics --- Suffrage --- Gouvernement représentatif --- Responsabilité ministérielle

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The search for bioactive secondary metabolites from marine organisms has been an active area of research since the 1950s. The distinct biodiversity of the marine environment has afforded a vast array of unique secondary metabolites, many of which possess potent biological activities. This Special Issue of Marine Drugs will highlight recent bioactive marine natural product studies conducted by southern hemisphere scientists on an array of marine organisms.

Medicine --- Sinularia --- Alcyoniidae --- anticancer activity --- lobane --- cembrane --- diterpene --- conotoxins --- ShK toxin --- ion channels --- docking --- molecular dynamics --- potential of mean force --- free energy perturbation --- bioactivity --- biosynthesis --- brominated secondary metabolites --- choline ester --- indole --- sea cucumber --- viscera --- saponins --- mass spectrometry --- MALDI --- ESI --- HPCPC --- triterpene glycosides --- structure elucidation --- bioactive compounds --- marine invertebrate --- Echinodermata --- holothurian --- Cnemidocarpa stolonifera --- taurine amide --- PC3 cell line --- immunofluorescence assay --- thiaplidiaquinone --- Aplidium --- ascidian --- thiazinoquinone --- apoptosis --- Jurkat --- cytotoxicity --- malaria --- farnesyltransferase --- synthesis --- thiaplakortone --- regioisomer --- tricyclic --- natural product scaffold --- X-ray --- crystal --- Plasmodium falciparum --- antiplasmodial --- cephalostatin --- mandelalide --- methicillin resistant Staphylococcus aureus --- MRSA PK --- bisindole alkaloids --- salternamide A (SA) --- HIF-1α --- PI3K/Akt/mTOR --- p42/p44 MAPK --- STAT3 --- cell death

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The search for bioactive secondary metabolites from marine organisms has been an active area of research since the 1950s. The distinct biodiversity of the marine environment has afforded a vast array of unique secondary metabolites, many of which possess potent biological activities. This Special Issue of Marine Drugs will highlight recent bioactive marine natural product studies conducted by southern hemisphere scientists on an array of marine organisms.

Medicine --- Sinularia --- Alcyoniidae --- anticancer activity --- lobane --- cembrane --- diterpene --- conotoxins --- ShK toxin --- ion channels --- docking --- molecular dynamics --- potential of mean force --- free energy perturbation --- bioactivity --- biosynthesis --- brominated secondary metabolites --- choline ester --- indole --- sea cucumber --- viscera --- saponins --- mass spectrometry --- MALDI --- ESI --- HPCPC --- triterpene glycosides --- structure elucidation --- bioactive compounds --- marine invertebrate --- Echinodermata --- holothurian --- Cnemidocarpa stolonifera --- taurine amide --- PC3 cell line --- immunofluorescence assay --- thiaplidiaquinone --- Aplidium --- ascidian --- thiazinoquinone --- apoptosis --- Jurkat --- cytotoxicity --- malaria --- farnesyltransferase --- synthesis --- thiaplakortone --- regioisomer --- tricyclic --- natural product scaffold --- X-ray --- crystal --- Plasmodium falciparum --- antiplasmodial --- cephalostatin --- mandelalide --- methicillin resistant Staphylococcus aureus --- MRSA PK --- bisindole alkaloids --- salternamide A (SA) --- HIF-1α --- PI3K/Akt/mTOR --- p42/p44 MAPK --- STAT3 --- cell death --- Sinularia --- Alcyoniidae --- anticancer activity --- lobane --- cembrane --- diterpene --- conotoxins --- ShK toxin --- ion channels --- docking --- molecular dynamics --- potential of mean force --- free energy perturbation --- bioactivity --- biosynthesis --- brominated secondary metabolites --- choline ester --- indole --- sea cucumber --- viscera --- saponins --- mass spectrometry --- MALDI --- ESI --- HPCPC --- triterpene glycosides --- structure elucidation --- bioactive compounds --- marine invertebrate --- Echinodermata --- holothurian --- Cnemidocarpa stolonifera --- taurine amide --- PC3 cell line --- immunofluorescence assay --- thiaplidiaquinone --- Aplidium --- ascidian --- thiazinoquinone --- apoptosis --- Jurkat --- cytotoxicity --- malaria --- farnesyltransferase --- synthesis --- thiaplakortone --- regioisomer --- tricyclic --- natural product scaffold --- X-ray --- crystal --- Plasmodium falciparum --- antiplasmodial --- cephalostatin --- mandelalide --- methicillin resistant Staphylococcus aureus --- MRSA PK --- bisindole alkaloids --- salternamide A (SA) --- HIF-1α --- PI3K/Akt/mTOR --- p42/p44 MAPK --- STAT3 --- cell death