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Neuropeptides --- Neurotransmitters --- Adenohypophysis --- Neuroendocrinology --- Pituitary Hormones, Anterior --- Brain

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Growth Hormone-Releasing Hormone --- Thyrotropin --- Pituitary Hormones, Anterior --- Acromegaly --- Calcitonin --- pharmacology --- secretion --- drug therapy

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The Pituitary, Fourth Edition, continues the tradition of a cogent blend of basic science and clinical medicine which has been the successful hallmark of prior editions. This comprehensive text is devoted to the pathogenesis, diagnosis, and treatment of pituitary disorders. The new edition has been extensively revised to reflect new knowledge derived from advances in molecular and cell biology, biochemistry, diagnostics, and therapeutics as they apply to the pituitary gland. The wide spectrum of clinical disorders emanating from dysfunction of the master gland is described in detail by experts in the field. Fundamental mechanisms underlying disease pathogenesis are presented to provide the reader with an in-depth understanding of mechanisms subserving both normal and disordered pituitary hormone secretion and action. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders. Chapters provide medical students, clinical and basic endocrinology trainees, endocrinologists, internists, pediatricians, gynecologists, and neurosurgeons with a comprehensive, yet integrated, text devoted to the science and art of pituitary medicine. Brings together pituitary experts from all areas of research and practice who take readers all the way from bench research, to genomic and proteomic analysis, clinical analysis, and new therapeutic approaches to pituitary disordersSaves researchers and clinicians time in quickly accessing the very latest details on a broad range of issues related to normal and diseased pituitary functionProvides a common language for endocrinologists, neurosurgeons, OB/GYNs, and endocrine researchers to discuss how the pituitary gland and hormones affect each major organ system.

Pituitary gland --- Pituitary Diseases --- Pituitary Gland --- Pituitary Hormones, Anterior --- Diseases. --- Pathophysiology. --- Physiology. --- physiopathology. --- diagnosis. --- physiology. --- Hypophysis cerebri --- Pituitary body --- Brain --- Endocrine glands --- Hypothalamo-hypophyseal system

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The pituitary, albeit a small gland, is known as the "master gland" of the endocrine system and contributes to a wide spectrum of disorders, diseases, and syndromes. Since the publication of the second edition of The Pituitary, in 2002, there have been major advances in the molecular biology research of pituitary hormone production and action and there is now a better understanding of the pathogenesis of pituitary tumors and clinical syndromes resulting in perturbation of pituitary function. There have also been major advances in the clinical management of pituitary disorders. Medical researchers and practitioners now better understand the morbidity and mortality associated with pituitary hormone hyposecretion and hypersecretion. Newly developed drugs, and improved methods of delivering established drugs, are allowing better medical management of acromegaly and prolactinoma. These developments have improved the worldwide consensus around the definition of a "cure" for pituitary disease, especially hormone hypersecretion, and hence will improve the success or lack of success of various forms of therapy. It is therefore time for a new edition of The Pituitary. The third edition will continue to be divided into sections that summarize normal hypothalamic-pituitary development and function, hypothalamic-pituitary failure, and pituitary tumors; additional sections will describe pituitary disease in systemic disorders and diagnostic procedures, including imaging, assessment of the eyes, and biochemical testing. The first chapter will be completely new - placing a much greater emphasis on physiology and pathogenesis. Two new chapters will be added on the Radiation and Non-surgical Management of the Pituitary and Other Pituitary Lesions. Other chapters will be completely updated and many new author teams will be invited. The second edition published in 2002 and there have been incredible changes in both the research and clinical aspects of the pituitary over the past 8 years - from new advances in growth hormones to pituitary tumor therapy. Feature Presents a comprehensive, translational source of information about the pituitary in one reference work Pituitary experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches. Clear presentation by endocrine researchers of the cellular and molecular mechanisms underlying pituitary hormones and growth factors as well as new techniques used in detecting lesions (within the organ) and other systemic disorders Clear presentation by endocrinologists and neuroendocrine surgeons of how imaging, assessment of the eyes, and biochemical testing can lead to new therapeutic approaches Benefit Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of issues related to normal and diseased pituitary function, as opposed to searching through thousands of journal articles. Provides a common language for endocrinologists, neurosurgeons, OB/GYNs, and endocrine researchers to discuss how the pituitary gland and hormones affect each major organ system Correct diagnosis (and therefore correct treatment) of pituitary disorders depends on a strong understanding of the pathophysiology of the organ as well as the molecular actions of pituitary hormones - practicing endocrinologists and other interested clinicians will benefit Endocrine researchers will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays

Pituitary gland --- Pituitary Diseases --- Pituitary Gland --- Pituitary Hormones, Anterior --- Diseases --- Physiology --- Treatment --- physiopathology --- diagnosis --- physiology --- Diseases. --- Pathophysiology. --- Physiology. --- Hypophysis cerebri --- Pituitary body --- Brain --- Endocrine glands --- Hypothalamo-hypophyseal system --- Pituitary gland - Diseases --- Pituitary gland - Physiology --- Pituitary gland - Diseases - Treatment --- Pituitary Diseases - physiopathology --- Pituitary Diseases - diagnosis --- Pituitary Gland - physiology --- Pituitary Hormones, Anterior - physiology

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Neuroendocrinology --- PITUITARY HORMONES, ANTERIOR --- NERVOUS SYSTEM DISEASES --- ENDOCRINE GLANDS --- Endocrine Diseases --- HORMONES --- Hypothalamus --- Endocrine System Diseases. --- Endocrine Glands. --- Hormones. --- Hypothalamus. --- Nervous System Diseases. --- Pituitary Hormones, Anterior. --- Endocrinology --- Neurology --- Neurohormones --- Adenohypophyseal Hormones --- Anterior Pituitary Hormones --- Hormones, Adenohypophyseal --- Hormones, Anterior Pituitary --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Preoptico-Hypothalamic Area --- Lamina Terminalis --- Area, Preoptico-Hypothalamic --- Areas, Preoptico-Hypothalamic --- Preoptico Hypothalamic Area --- Preoptico-Hypothalamic Areas --- Hormone --- Hormone Receptor Agonists --- Agonists, Hormone Receptor --- Receptor Agonists, Hormone --- Endocrine Glands --- Endocrine Gland --- Gland, Endocrine --- Diseases of Endocrine System --- Disease, Endocrine --- Disease, Endocrine System --- Diseases, Endocrine --- Diseases, Endocrine System --- Endocrine Disease --- Endocrine System Disease --- System Disease, Endocrine --- System Diseases, Endocrine --- Endocrine System Diseases --- Hormones --- Nervous System Diseases --- Pituitary Hormones, Anterior --- Endocrine glands. --- Nervous system --- Diseases. --- Diseases