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"Fighting the Opioid Epidemic: The Role of Providers and the Clinical Laboratory in Understanding Who Is Vulnerable covers the important aspects that are essential in fighting the opioid epidemic. This succinct reference highlights how the toxicology laboratory can play a vital role in fighting the opioid epidemic by implementing a robust system for drugs of abuse testing as well as drug testing in pain management patients. It targets health care professionals in a technical manner, discussing polymorphisms of important genes that may be associated with increased vulnerability of alcohol and drug addiction to an individual. Covers all important aspects of opioid abuse, including genetic and environmental factors Discusses pharmacology, toxicology and the pharmacogenomics related to opioid metabolism Presents genetic and environmental factors associated with those vulnerable to opioid addiction, as well as the pitfalls of drug testing in pain management."--

Opioid abuse. --- Opioid addiction --- Opioid habit --- Drug abuse

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Out of 238 million American adults, 100 million live in chronic pain. And yet the press has paid more attention to the abuses of pain medications than the astoundingly widespread condition they are intended to treat. Ethically, the failure to manage pain better is tantamount to torture. When chronic pain is inadequately treated, it undermines the body and mind. Indeed, the risk of suicide for people in chronic pain is twice that of other people. Far more than just a symptom, writes author Judy Foreman, chronic pain can be a disease in its own right -- the biggest health problem facing America

Chronic pain --- Opioid abuse --- Pain --- Opioid addiction --- Opioid habit --- Drug abuse --- Persistent pain --- Diseases --- Treatment --- History. --- Alternative treatment.

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This text will provide readers with a thorough review of the complex condition of chronic pain and addictions. The book was originally commissioned due to the need in the field for more literature on the topic. This concise pocket book will review epidemiology, clinical features, diagnosis, and medical management of both chronic pain and addiction. Busy healthcare professionals will benefit from this text, which will not only cover the foundation of the management of both conditions and together, but discuss up-to-date national and international treatment guidelines, upcoming therapies and REMS.

Medicine & Public Health. --- Pain Medicine. --- Medicine. --- Médecine --- Chronic pain -- Treatment. --- Opioid abuse. --- Medicine --- Surgery & Anesthesiology --- Health & Biological Sciences --- Anesthesiology --- Pathology --- Chronic pain --- Treatment. --- Opioid addiction --- Opioid habit --- Pain medicine. --- Drug abuse --- Algiatry

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This unique and timely title offers a comprehensive assessment of the previously underappreciated risks and potentially overstated benefits of chronic opioid therapy. It does so by approaching the rampant problem of opioid abuse and addiction – currently labeled an epidemic in the United States -- from a public health/epidemiologic perspective. That is, following a thorough overview in Part 1 that compares (and contrasts) classic infectious disease epidemiology concepts with the epidemic, the book categorizes our current understanding of basic science and best clinical practices in opioid therapy in terms of Agent (opioid), Vector (prescriber) and Host (patient) factors. The majority of the book, which includes a plethora of instructional case studies, is organized according to these three arenas. Opioid Dependence: A Clinical and Epidemiologic Approach is designed to update all clinicians on opioid basic science, current areas of drug improvement research and development, alternatives to opioid therapy, evidence-based indications for opioid therapy, and clinical strategies for preventing and overcoming opioid dependence. Importantly, an overview of clinical practice guidelines from the American Society of Addiction Medicine, with its biopsychosocial-spiritual “multidimensional assessment” focus is provided, along with a discussion of medication-assisted treatment, organized by the three currently FDA-approved pharmacotherapeutics (methadone, buprenorphine and naltrexone). Developed for practitioners at every level, this ground-breaking title offers a fresh and novel approach to improving the care and outcomes of patients receiving opioid therapy.

Medicine. --- General practice (Medicine). --- Internal medicine. --- Neurology. --- Pain medicine. --- Psychiatry. --- Medicine & Public Health. --- Pain Medicine. --- Internal Medicine. --- General Practice / Family Medicine. --- Medicine, Internal --- Clinical sciences --- Medical profession --- Opioid abuse --- Chemotherapy. --- Opioid addiction --- Opioid habit --- Drug abuse --- Family medicine. --- Family practice (Medicine) --- General practice (Medicine) --- Medicine --- Physicians (General practice) --- Medicine and psychology --- Mental health --- Psychology, Pathological --- Nervous system --- Neuropsychiatry --- Diseases --- Algiatry --- Neurology .

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Substance use disorder (SUD) and opioid use disorder are significant public health threats that affect millions of Americans each year. To help address overdose deaths and lack of access to treatment, the Comprehensive Addiction and Recovery Act (CARA) was signed into law on July 22, 2016. CARA is extensive legislation intended to address many facets of the opioid epidemic, including prevention, treatment, recovery, law enforcement, criminal justice reform, and overdose reversal. It authorizes more than $181 million each year in new funding to fight the opioid epidemic and it requires the implementation of programs and services across the United States to address SUD and recovery. Following the passage of CARA, the Departments of Education, Health and Human Services (HHS), and Labor, along with the 2018 Related Agencies Appropriations Act, included appropriations for a study of the Substance Abuse and Mental Health Services Administration (SAMHSA) components in CARA, to be conducted by the National Academies of Sciences, Engineering, and Medicine. In response to this charge, the National Academies formed an ad hoc committee to review outcomes achieved by four programs funded by SAMHSA through CARA: State Pilot Grant Program for Treatment for Pregnant and Postpartum Women (PPW-PLT), Building Communities of Recovery (BCOR), Improving Access to Overdose Treatment (OD Treatment Access), and First Responders (FR-CARA). The committee's review is designed to result in three reports over 5 years. This report, the second in the series, reviews reported outcomes and metrics to assess progress toward achieving program goals.

Space shuttles --- Reusable space vehicles --- Propulsion systems --- Outcome assessment (Medical care) --- Heroin abuse --- Opioid abuse --- Heroin addiction --- Heroin habit --- Drug abuse --- Opioid addiction --- Opioid habit --- Assessment of outcome (Medical care) --- Outcome evaluation (Medical care) --- Outcome measures (Medical care) --- Outcomes assessment (Medical care) --- Outcomes measurement (Medical care) --- Outcomes research (Medical care) --- Patient outcome assessment --- Medical care --- Prevention. --- Evaluation --- Outer space --- Outer space. --- United States. --- Exploration