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Eye --- Ocular pharmacology --- Ophthalmic drugs --- Therapeutics, Ophthalmological --- Ocular therapeutics --- Ophthalmological therapeutics --- Therapeutics, Ocular --- Materia medica, Ophthalmological --- Ophthalmic agents --- Drugs --- Ophthalmopharmacology --- Pharmacology --- Diseases --- Drug effects --- Effect of drugs on

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This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of nanotechnology and nano­ material design for biological applications. For this field to evolve, there is a need to understand the dynamic forces and molecular components that shape these interactions. While it is impossible to describe with certainty all the bio­ physicochemical interactions at play at the interface, we are at a point where the pockets of assembled knowledge are providing a conceptual framework to guide this exploration, and review the impact on future product development. The book is intended as a valuable resource for academics and pharmaceutical scientists working in the field of polymers, polymers materials for drug delivery, drug delivery systems and ophthalmic drug delivery systems, in addition to medical and health care professionals in these areas.

Medicine. --- Pharmaceutical technology. --- Biotechnology. --- Ophthalmology. --- Biomedicine. --- Pharmaceutical Sciences/Technology. --- Ophthalmic drugs. --- Materia medica, Ophthalmological --- Ophthalmic agents --- Drugs --- Therapeutics, Ophthalmological --- Ocular pharmacology --- Medicine --- Eye --- Chemical engineering --- Genetic engineering --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Diseases

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This book comprises an integrated review of ocular therapeutics across all relevant fields. It addresses the real-world requirements of ophthalmologists, pharmacists and optometrists, as observed through working alongside these practitioners for two decades. Knowledge surrounding agents used in ophthalmic practice has, historically, been scattered. The book facilitates understanding of ocular drug therapy by compiling all key aspects of the pharmacology, toxicology, pharmaceutical science, ocular biochemistry and cell biology of these agents. Chapters detail drug transfer across barriers, systemic toxicity of topically applied drugs, autonomic drugs used for diagnostics, as well as anti-inflammatory, antiallergic, glaucoma and antimicrobial therapies, and avenues for the development of new ocular drugs. Applications of extemporaneously prepared formulations are described to inform day-to-day clinical practice. The use of mucoadhesive polymers in tear substitutes, ocular drug delivery systems, stem cell therapy, pharmacogenomics and antiangiogenic ocular chemotherapy are also explored. The book also provides insights from drugs of herbal origin, and a historical perspective on drugs for ocular use. Practicing and resident ophthalmologists, optometrists, pharmacists, nursing professionals, scholars in ocular drug research and students will equally benefit from this comprehensive guide.

Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Toxicology. --- Ophthalmology. --- Pharmacology/Toxicology. --- Medicine --- Eye --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Diseases --- Toxicology --- Ocular pharmacology. --- Ophthalmic drugs. --- Treatment. --- Eyeball --- Eyes --- Visual system --- Face --- Photoreceptors --- Vision --- Materia medica, Ophthalmological --- Ophthalmic agents --- Drugs --- Therapeutics, Ophthalmological --- Ocular pharmacology --- Ophthalmopharmacology --- Ophthalmic drugs --- Drug effects --- Effect of drugs on --- Pharmacology. --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Pharmacy --- Physiological effect

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This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles. .

Ophthalmic drugs. --- Drug delivery systems. --- Delivery systems, Drug --- Drug administration technology --- Drug delivery technology --- Drugs --- Pharmaceutical technology --- Materia medica, Ophthalmological --- Ophthalmic agents --- Therapeutics, Ophthalmological --- Ocular pharmacology --- Delivery systems --- Pharmaceutical technology. --- Ophthalmology. --- Pharmaceutical Sciences/Technology. --- Medicine --- Eye --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Diseases

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The updated edition of this popular pocket guide includes new drugs available and FDA-approved since publication of the first edition and also guidance on using the growing number of drugs now prescribed for off-label purposes, such as anti-VEGF agents, used in cancer treatments, which are also being used to stop cell growth in age-related macular degeneration. Drugs are grouped by presenting disease (e.g., glaucoma, retinal disease, cataracts), and readers may also access information via the Product Index or the Subject Index. The entire book is presented in a table format to facilitate quick look-up.

Eye Diseases -- Drug therapy. --- Ocular pharmacology. --- Ophthalmic drugs. --- Eye --- Therapeutic Uses --- Chemicals and Drugs --- Diseases --- Publication Formats --- Therapeutics --- Publication Characteristics --- Pharmacologic Actions --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemical Actions and Uses --- Anti-Infective Agents --- Eye Diseases --- Handbooks --- Pharmaceutical Preparations --- Drug Therapy --- Anti-Inflammatory Agents --- Medicine --- Health & Biological Sciences --- Ophthalmology & Optometry --- Ophthalmopharmacology --- Materia medica, Ophthalmological --- Ophthalmic agents --- Drug effects --- Effect of drugs on --- Medicine. --- Ophthalmology. --- Medicine & Public Health. --- Pharmacology --- Ophthalmic drugs --- Drugs --- Therapeutics, Ophthalmological --- Ocular pharmacology