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Nuclear Structure and Gene Expression assimilates the contributions of genome organization and of the components of the nuclear matrix to the control of DNA and RNA synthesis. Nuclear domains which accommodate DNA replication and gene expression are considered in relation to short-term developmental and homeostatic requirements as well as to long-term commitments to phenotypic gene expression in differentiated cells. Consideration is given to the involvement of nuclear structure in gene localization as well as to the targeting and concentration of transcription factors. Aberrations in n

Nuclear matrix. --- Gene expression. --- Genes --- Nuclear protein matrix --- Nuclear scaffold --- Nuclear skeleton --- Nucleoskeleton --- Expression --- Genetic regulation --- Cell nuclei --- Nonhistone chromosomal proteins --- Basic Sciences. Genetics --- Molecular Genetics.