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Cell cycle --- Cell Division --- Cycle cellulaire --- Cell cycle. --- Histology. Cytology --- Cell Division. --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms

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It is now known that the adult mammalian brain undergoes repair and renewal from pools of stem cells and that cell cycle alteration may cause a variety of neurological disorders ranging from autism to brain tumors. In The Cell Cycle in the Central Nervous System, prominent researchers, physicians, engineers, and pharmacologists join forces to delineate how the brain is a complex organ composed of widely varying cell types, including blood vessels, and what its cellular-based disorders may be. Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system (CNS) to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle. State-of-the-art and readily understandable, The Cell Cycle in the Central Nervous System illuminates our understanding of how brain development, disease, renewal, and repair may be mediated by vasculogenesis, neurogenesis, and the immune system, and offers an exciting variety of new research opportunities for all those investigating brain tumors, neurodevelopment, and neurological disorders.

Central nervous system --- Cell cycle. --- Growth. --- Differentiation. --- Nervous system, Central --- Nervous system --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms --- Neurosciences. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences

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The ability to detect and quantify apoptosis, to understand its biochemistry, and to identify its regulatory genes and proteins is crucial to biomedical research. In Apoptosis: Methods and Protocols, Second Edition, expert researchers describe the techniques to best investigate the critical steps involved in the apoptotic process. Presented from several different research perspectives, the volume contains sections covering detection of apoptosis, detection of non-apoptotic cell death, modifications of apoptotic proteins during apoptosis, the analysis of its major regulators, as well as analysis of apoptosis in different organs and in model organisms. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Apoptosis: Methods and Protocols, Second Edition constitutes a key technical reference to the significant methodologies used in the field, and offers beginners and experienced researchers powerful tools to illuminate the phenomena of programmed cell death.

Cytology. --- Cell cycle. --- Cell Biology. --- Cell Cycle Analysis. --- Apoptosis. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms

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Cell cycle checkpoints control the fidelity and orderly progression of eukaryotic cell division. By controlling the orderly progression of critical cell cycle events such as DNA replication and chromosome segregation and ensuring proper repair of damaged DNA, cell cycle checkpoints function to ensure genome integrity. Mechanisms of checkpoint controls are not only the research focus of investigators interested in mechanisms that regulate the cell cycle, but are also the interests of researchers studying cancer development as it is increasingly clear that loss of cell cycle checkpoints, which leads to genomic instability as a result, is a hallmark of tumorigenesis. Cell Cycle Checkpoints: Methods and Protocols provides detailed descriptions of methodologies currently employed by researchers in the field, including those commonly used in the mammalian, yeast, C. elegans, Drosophila, and Xenopus model systems. Each chapter describes a specific technique or protocol, such as a method to induce cell cycle checkpoints in a particular model system, to synchronize a population of cells to allow observations of cell cycle progression, to identify genes involved in checkpoint regulation, and to study particular protein components of cell cycle checkpoint pathways. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and easily accessible, Cell Cycle Checkpoints: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies in an effort to further our knowledge of this essential field.

Cytology. --- Cell cycle. --- Cell Biology. --- Cell Cycle Analysis. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms

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A collection of new reviews and protocols from leading experts in cell cycle regulation, Cell Cycle Control: Mechanisms and Protocols, Second Edition presents a comprehensive guide to recent technical and theoretical advancements in the field. Beginning with the overviews of various cell cycle regulations, this title presents the most current protocols and state-of-the-art techniques used to generate latest findings in cell cycle regulation, such as protocols to analyze cell cycle events and molecules. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and easily accessible, Cell Cycle Control: Mechanisms and Protocols, Second Edition will be a valuable resource for a wide audience, ranging from the experienced cell cycle researchers looking for new approaches to the junior graduate students giving their first steps in cell cycle research.

Cytology. --- Cell cycle. --- Cell Biology. --- Cell Cycle Analysis. --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Mitotic cycle --- Nuclear cycle (Cytology) --- Biological rhythms