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Ancien Testament --- Antico Testamento --- Bibel. Altes Testament --- Bible hébraïque --- Bible. Ancien Testament --- Bible. Antico Testamento --- Bible. Hebrew Bible --- Bible. Hebrew Scriptures --- Bible. Kitve-kodesh --- Bible. Mikra --- Bible. O.T. --- Bible. Old Testament --- Bible. Palaia Diatheke --- Bible. Pentateuch, Prophets, and Hagiographa --- Bible. Sean-Tiomna --- Bible. Stary Testament --- Bible. Tanakh --- Bible. Tawrat --- Bible. Torah, Nevi'im u-Khetuvim --- Bible. Torah, Nevi'im, Ketuvim --- Bible. Velho Testamento --- Bijbel [Hebreeuwse ] --- Bijbel. Oud Testament --- Chansons sacrées --- Gewijde liederen --- Hebreeuwse bijbel --- Hebrew Bible --- Hebrew Scriptures --- Hébraïque [Bible ] --- Kitve-kodesh --- Mikra --- Old Testament --- Oud Testament --- Palaia Diatheke --- Pentateuch, Prophets, and Hagiographa --- Sacred songs --- Sean-Tiomna --- Stary Testament --- Tanakh --- Tawrat --- Torah, Nevi'im u-Khetuvim --- Torah, Nevi'im, Ketuvim --- Velho Testamento --- Music --- Early works to 1800

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Paul Gerson Unna’s “Abtropfung” theory that nevi develop through migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the “Hochsteigerung” theory postulated the reverse pattern of migration based on newly acquired observations from histopathology and studies of embryogenesis. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of the aforementioned theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis.

Medicine. --- Nevus -- Physiopathology. --- Skin neoplasms -- Physiopathology. --- Mole (Dermatology) --- Skin Diseases --- Neoplasms by Site --- Nevi and Melanomas --- Neoplasms by Histologic Type --- Neoplasms --- Skin and Connective Tissue Diseases --- Diseases --- Skin Neoplasms --- Nevus --- Medicine --- Health & Biological Sciences --- Dermatology --- Skin --- Melanoma. --- Diseases. --- Moles (Dermatology) --- Naevus --- Malignant melanoma --- Melanocytic tumor --- Cutaneous diseases --- Dermatoses --- Dermatology. --- Oncology. --- Medicine & Public Health. --- Cancer --- Neuroendocrine tumors --- Oncology  . --- Tumors

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This book provides the first full-length literary and form-critical study of Aaron, a central yet long-neglected biblical figure. Using a range of methodologies, it carefully examines key Pentateuchal texts which present Aaron in multiple ways.

221-05 --- 221 --- 221 Bible: Ancien Testament --- 221 Bijbel: Oud Testament --- Bible: Ancien Testament --- Bijbel: Oud Testament --- 221-05 Personen in het Oude Testament --- Personen in het Oude Testament --- Aaron --- Bible. --- Chumash --- Five Books of Moses --- Ḥamishah ḥumshe Torah --- Ḥumash --- Kitāb-i Muqqadas --- Mose Ogyŏng (Book of the Old Testament) --- Pentateuch --- Pi︠a︡toknizhīe Moiseevo --- Sefer Ḥamishah ḥumshe Torah --- Tawrāh --- Torà (Pentateuch) --- Torah (Pentateuch) --- Tʻoris xutʻcigneuli --- Ureta --- תורה --- Haftarot --- Criticism, interpretation, etc. --- Ancien Testament --- Antico Testamento --- Bibel. Altes Testament --- Bible hébraïque --- Bible. Ancien Testament --- Bible. Antico Testamento --- Bible. Hebrew Bible --- Bible. Hebrew Scriptures --- Bible. Kitve-kodesh --- Bible. Mikra --- Bible. O.T. --- Bible. Old Testament --- Bible. Palaia Diatheke --- Bible. Pentateuch, Prophets, and Hagiographa --- Bible. Sean-Tiomna --- Bible. Stary Testament --- Bible. Tanakh --- Bible. Tawrat --- Bible. Torah, Nevi'im u-Khetuvim --- Bible. Torah, Nevi'im, Ketuvim --- Bible. Velho Testamento --- Bijbel [Hebreeuwse ] --- Bijbel. Oud Testament --- Hebreeuwse bijbel --- Hebrew Bible --- Hebrew Scriptures --- Hébraïque [Bible ] --- Kitve-kodesh --- Mikra --- Old Testament --- Oud Testament --- Palaia Diatheke --- Pentateuch, Prophets, and Hagiographa --- Sean-Tiomna --- Stary Testament --- Tanakh --- Tawrat --- Torah, Nevi'im u-Khetuvim --- Torah, Nevi'im, Ketuvim --- Velho Testamento --- Aaron, --- Aron --- אהרן --- Aharon --- Hārūn b. ʻImrān --- هارون --- Hārūn --- Аарон --- Ααρών --- 아론 --- Aronne --- Aroni --- Ārons --- Aaronas --- アロン --- Aarão --- Arão --- Арон --- Aaroona --- אהרן, --- Aharon, --- Áárọ́nì --- 亞倫 --- Yalun --- Ya lun --- Exegese Oude Testament --- Bijbelcommentaar --- Bijbelse theologie

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Skin inflammation is associated with a wide range of conditions which represent major health issues worldwide. Skin and mucosal surfaces represent the primary interface between the human body and the environment, susceptible to numerous factors whose action results in diseases produced by chemical substances, mechanical trauma, microbial agents, radiation, etc. Inflammation, a complex network of interactions between soluble molecules and cells, represents the main modality of the skin’s response to injuries. Numerous studies have revealed close links between chronic inflammation, oxidative stress, and carcinogenesis. Chronic inflammation induces the activation of various cell types and an increase in the production of reactive oxygen species, promoting the initiation of a malignant process. Identifying specific biomarkers is essential for understanding molecular mechanisms and developing therapies appropriate to the patient’s characteristics.Personalized medicine is an emerging field of medicine that has the potential to predict which therapy will be safe and efficacious for specific patients using an individual’s genetic profile to guide decisions regarding the diagnosis, treatment, as well as prevention of disease. This book gathers articles that present recent advancements in research involving the mechanisms that underlie the development of inflammatory skin disorders, skin and mucosal inflammation in general.

sea-buckthorn seed oil --- long-chain fatty acids --- skin dysplastic keratinocytes --- UVA --- CD36 --- SR-B2 --- atopic dermatitis --- eczema --- JAK inhibitors --- systematic review --- meta-analysis --- evidence-based medicine --- immune-mediated skin diseases --- target therapy --- skin conditions and systemic inflammatory diseases --- systemic sclerosis --- biomarker --- calumenin --- S100A6 --- cytohesin 2 --- cannabinoids --- inflammation --- gut-lung-skin barrier --- signaling pathways --- inflammatory biomarkers --- psoriasis vulgaris --- prevalence --- comorbidities --- risk factors --- systemic lupus erythematous --- lupus nephritis --- lipid peroxidation --- DNA oxidation --- oxidized proteins --- carbohydrate oxidation --- antioxidative stress strategies --- biomarkers --- IgY --- psoriatic dermatitis --- imiquimod --- C57 BL/6 mice --- alginate --- biomaterial --- dressing --- fibers --- hydrogel --- nanofibers --- commercially available --- wound care --- wound healing --- cutaneous melanoma --- epigenetic regulation --- drug resistance --- therapeutic targets --- epigenetic therapy --- immune response --- Sutton nevi --- halo nevi --- skin tumor --- psoriasis --- proteome analysis --- estrogen --- menopause --- cSCC --- AK --- sialylation --- sialyltransferase --- sialidase --- COVID-19 --- pyoderma gangrenosum --- immunosuppression --- cyclosporine --- corticosteroids --- autoinflammatory disease --- androgenic alopecia --- clinical trial --- hair density --- platelet-rich plasma --- n/a

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Melanoma is an increasingly important public health problem. Although the cause of most malignant melanomas – over-exposure to ultraviolet light – is well known, effective treatment has remained challenging. The past several years have been marked by extraordinary developments in melanoma treatment in the arena of targeted therapeutics. This book describes these ground-breaking discoveries and their implications for clinical use. As melanoma biology is increasingly understood, so the development of targeted therapies for this disease is spurred ahead. This book covers both established signal transduction inhibitors and the fascinating emerging realm of molecularly-guided immunotherapies. This benchmark book provides the most up-to-date information on the new breed of melanoma therapies. Composed of the works of major researchers and clinicians, this book offers new insights, novel approaches, and promising data for effective treatment planning. Illuminating the latest advances in the field, it is a solid resource for clinical oncologists, translational scientists, and basic cancer researchers.

Melanoma -- drug therapy. --- Melanoma -- Treatment. --- Molecular Targeted Therapy -- methods. --- Melanoma --- Investigative Techniques --- Neuroendocrine Tumors --- Nevi and Melanomas --- Therapeutics --- Neoplasms by Histologic Type --- Neuroectodermal Tumors --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms, Nerve Tissue --- Neoplasms, Germ Cell and Embryonal --- Neoplasms --- Diseases --- Molecular Targeted Therapy --- Methods --- Drug Therapy --- Medicine --- Health & Biological Sciences --- Oncology --- Treatment --- Treatment. --- Malignant melanoma --- Melanocytic tumor --- Medicine. --- Cancer research. --- Oncology. --- Medicine & Public Health. --- Cancer Research. --- Cancer --- Neuroendocrine tumors --- Oncology  . --- Tumors --- Cancer research