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Book
Antipsychotic drugs
Author:
ISBN: 1634844181 9781634844185 1634844033 9781634844031 9781634844185 Year: 2016 Publisher: New York


Book
Antipsychotic drugs
Authors: --- ---
ISBN: 1622574591 9781622574599 9781621000716 1621000710 Year: 2013 Publisher: New York

Antipsychosis
Authors: ---
ISBN: 354060118X 3642646530 3642610072 Year: 1996 Volume: 120 Publisher: Berlin ; Heidelberg ; New York Springer


Book
Antipsychotic drugs : pharmacodynamics and pharmacokinetics.
Authors: --- ---
ISBN: 0080196888 Year: 1976 Volume: v. 25 Publisher: Oxford Pergamon


Book
Psychotic Disorders : A Practical Guide
Author:
ISBN: 3030294501 3030294498 Year: 2020 Publisher: Cham : Springer International Publishing : Imprint: Humana,

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Abstract

This book provides clear and concise guidance for clinicians when they encounter a patient with psychosis, starting with the medical work-up to arrive at a diagnosis and ending with the comprehensive care for patients with established schizophrenia. It covers the optimal use of medications (emphasizing safe use) but also addresses other treatment approaches (psychological treatments, rehabilitation) and the larger societal context of care, including how to work effectively in complex systems. It uniquely condenses the literature into teaching points without simplifying too much, effectively serving as a learning tool for trainees and professionals. For this second edition, the book was extensively updated and its content expanded, with new figures as well. Each chapter begins with an initial summary and includes Tips and Key Points in text boxes. Each chapter also includes links to external websites and additional readings. The book contains clinical and practical wisdom for clinicians who are treating real patients at the front lines, setting it apart from all other texts. Psychotic Disorders is an excellent resource for medical students, early career professionals such as trainees and fellows, and related clinicians seeking additional training and resources, including those in psychiatry, psychology, neurology, and all others.


Book
Phenothiazines and structurally related drugs
Author:
ISBN: 0911216618 9780911216615 Year: 1974 Volume: 9 Publisher: New York (N.Y.): Raven Press

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Book
Guidelines for neuroleptic relapse prevention in schizophrenia : proceedings of a consensus conference held April 19-20, 1989, in Bruges, Belgium
Authors: ---
ISBN: 3540539859 364286922X 0387539859 9783540539858 Year: 1991 Publisher: Berlin ; New York : Springer Verlag,


Book
Genetic Influences on Response to Drug Treatment for Major Psychiatric Disorders
Authors: ---
ISBN: 3319270389 3319270400 Year: 2016 Publisher: Cham : Springer International Publishing : Imprint: Adis,

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Abstract

Written by global experts, this book provides a modern comprehensive insight into the pharmacogenetics of treatment of major psychoses: schizophrenia, bipolar disorder and depression. The pharmacogenomics of three categories of the most important psychiatric drugs, antipsychotics, antidepressants and mood stabilizers, has been updated and reviewed. Some promising directions and perspectives for future research in pharmacogenetics in major psychoses are indicated. They are, among others, connected with the development of new methods in molecular genetics and with linking pharmacogenetics assessment with biomarkers, including neuroimaging ones. Finally, the attempts to use pharmacogenetics of antipsychotic, antidepressant and mood-stabilizing drugs in practice are presented. New pharmacogenetic tools may greatly contribute to introducing personalized medicine into psychiatric clinical practice.


Book
Current antipsychotics
Authors: ---
ISSN: 01712004 ISBN: 3642445470 3642257607 3642257615 1283849402 Year: 2012 Volume: v. 212 Publisher: New York : Springer,

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Abstract

Six decades after the serendipitous discovery of chlorpromazine as an antipsychotic and four decades after the launch of clozapine, the first atypical or second generation antipsychotic, psychopharmacology has arrived at an important crossroad. It is clear that pharmacological research and pharmaceutical development must now focus on complementary or even alternative mechanisms of action to address unmet medical  needs, i.e. poorly treated domains of schizophrenia, improved acceptance by patients, better adherence to medication, safety in psychoses in demented patients, and avoiding cardiac and metabolic adverse effects. The first completely novel mechanisms evolving from our insights into the pathophysiology of psychotic disorders, especially the role of glutamatergic mechanisms in schizophrenia, are now under development, and further principles are on the horizon. This situation, in many respects similar to that when the initial second-generation antipsychotics became available, can be rewarding for all.  Preclinical and clinical researchers now have the opportunity to confirm their hypotheses and the pharmaceutical industry may be able to develop really novel classes of therapeutics. When we were approached by the publishers of the Handbook of Experimental Pharmacology to prepare a new volume on antipsychotics, our intention was to capture both, the accumulated preclinical and clinical knowledge about current antipsychotics as well as prospects for new and potentially more specific antischizophrenia principles. These efforts should be based on the pathophysiology of the diseases and the affected neurotransmitter systems. Since preclinical research on antipsychotic compounds is only reliable when intimately linked through translational aspects to clinical results, we decided to include clinical science as well. It turned out that that this endeavor could not be covered by a single volume. We thank the editorial board and the publishers for supporting our decision to prepare two volumes: Current Antipsychotics and Novel Antischizophrenia Treatments. These topics cannot really be separated from one another and should be seen as a composite entity despite the somewhat arbitrary separation of contributions into two volumes. The continuing challenges of developing improved and safer antipsychotic medications remain of concern and are discussed in the first volume. The new opportunities for the field to develop and license adjunctive treatments for the negative symptoms and cognitive deficits that are treated inadequately by existing compounds have been incentivized recently and provide the focus for the second volume. We hope these collective contributions will facilitate the development of improved treatments for the full range of symptomatology seen in the group of schizophrenias and other major psychotic disorders. Gerhard Gross, Ludwigshafen, Germany Mark A. Geyer, La Jolla, CA This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. Non-schizophrenia indications will be covered to some extent, but not exhaustively.

Keywords

Antipsychotic agents -- Therapeutic use. --- Antipsychotic drugs -- Controlled release. --- Injections. --- Antipsychotic drugs --- Tranquilizing Agents --- Schizophrenia and Disorders with Psychotic Features --- Therapeutics --- Psychotropic Drugs --- Central Nervous System Depressants --- Mental Disorders --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Central Nervous System Agents --- Physiological Effects of Drugs --- Psychiatry and Psychology --- Pharmacologic Actions --- Therapeutic Uses --- Chemical Actions and Uses --- Chemicals and Drugs --- Antipsychotic Agents --- Drug Therapy --- Psychotic Disorders --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Antipsychotic drugs. --- Antipsychotic agents --- Antipsychotics --- Major tranquilizers --- Major tranquilizing agents --- Major tranquilizing drugs --- Neuroleptic agents --- Neuroleptic drugs --- Neuroleptics --- Neurolepts --- Tranquilizing drugs, Major --- Medicine. --- Pharmacy. --- Neurosciences. --- Pharmacology. --- Behavioral sciences. --- Proteins. --- Neurobiology. --- Biomedicine. --- Pharmacology/Toxicology. --- Receptors. --- Behavioral Sciences. --- Psychotropic drugs --- Psychoses --- Chemotherapy --- Toxicology. --- Cell receptors. --- Animal behavior. --- Chemistry --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Animals --- Animals, Habits and behavior of --- Behavior, Animal --- Ethology --- Animal psychology --- Zoology --- Ethologists --- Psychology, Comparative --- Neurosciences --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Binding sites (Biochemistry) --- Cell membranes --- Proteins --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Chemicals --- Poisoning --- Poisons --- Behavior --- Toxicology --- Proteins . --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Drug effects --- Medical pharmacology --- Pharmacy --- Physiological effect

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