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This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Neural crest.

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Animal embryology and growth --- Neural crest.

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Human genetics --- Orthopaedics. Traumatology. Plastic surgery --- Human embryology --- Face --- Abnormalities --- Genetic aspects --- Congresses --- Skull --- Neural crest

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The book offers readers an understanding of the development of neural crest cells, which is crucial as many birth defects and tumours are of neural crest origin. The neural crest is a transient tissue of the vertebrate embryo. It originates from the future spinal cord and neural crest stem cells emigrate from this location to various places in the embryo, giving rise to many different cell types and tissues. Neural crest derivatives include the peripheral nervous systems, endocrine cells such as the adrenal medulla, smooth musculature of the cardiac outflow tract and great blood vessels, as we

Neural crest --- Stem cells --- Crest, Neural --- Ganglionic crest --- Ganglionic ridge --- Embryology --- Nervous system --- Research.

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Aortic Coarctation --- Aortic Valve --- Family Health --- Heart Defects, Congenital --- Neural Crest --- surgery --- abnormalities --- complications --- embryology