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Memory disorders --- Memory Disorders --- Nervous system --- Nervous System Diseases --- Diseases --- Complications --- Wounds and injuries --- etiology --- complications --- Organs (Anatomy) --- Neurosciences --- Impairment, Memory --- Memory, Disorders of --- Memory impairment --- Paramnesia --- Cognition disorders --- Diseases&delete& --- Wounds and injuries&delete& --- Nervous system - Diseases - Complications --- Nervous system - Wounds and injuries - Complications --- Memory Disorders - etiology --- Nervous System Diseases - complications
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Since the beginning of the 21st Century there has been a rapid increase in our understanding of the cellular trafficking mechanisms of molecular chaperones in eukaryotes and in prokaryotes. In the former, molecular chaperone trafficking can occur between the various cellular compartments, with concomitant movement of other proteins. Such events can also result in the release of molecular chaperones from cells. In bacteria, molecular chaperones are involved in the trafficking of other proteins and are themselves released into the external milieu. The increasing appreciation of the role of molecular chaperones and Protein-Folding Catalysts in the interplay between bacteria and the cells of their hosts is now an important area of research for understanding the mechanisms of infectious diseases. This volume brings together experts in the biochemistry, cellular biology, immunology and molecular biology of molecular chaperones and Protein-Folding Catalysts with a focus on the mechanisms of cellular trafficking of these proteins and the role of these variegated trafficking mechanisms in both human and animal health and disease.
Brain -- Wounds and injuries -- Pathophysiology. --- Central Nervous System -- drug effects. --- Central Nervous System -- injuries. --- Central nervous system -- Wounds and injuries -- Chemotherapy. --- Central nervous system -- Wounds and injuries -- Pathophysiology. --- Molecular chaperones --- Eukaryotic cells --- Prokaryotes --- Proteins --- Heat shock proteins --- Diseases --- Biological Science Disciplines --- Biological Transport --- Amino Acids, Peptides, and Proteins --- Metabolism --- Natural Science Disciplines --- Disciplines and Occupations --- Metabolic Phenomena --- Chemicals and Drugs --- Phenomena and Processes --- Physiology --- Protein Transport --- Heat-Shock Proteins --- Molecular Chaperones --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Physiological transport --- Molecular chaperones. --- Eukaryotic cells. --- Prokaryotes. --- Heat shock proteins. --- Diseases. --- Physiological transport. --- Human beings --- Illness --- Illnesses --- Morbidity --- Sickness --- Sicknesses --- Stress proteins --- Monera --- Procaryotae --- Procaryotes --- Prokaryonta --- Prokaryotae --- Prokaryotic protists --- Eucaryotic cells --- Chaperone proteins --- Chaperones, Molecular --- Chaperonins --- Medicine. --- Human physiology. --- Molecular biology. --- Neurosciences. --- Life sciences. --- Biomedicine. --- Human Physiology. --- Life Sciences, general. --- Molecular Medicine. --- Biosciences --- Sciences, Life --- Science --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Human biology --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Medicine --- Epidemiology --- Health --- Sick --- Cells --- Protista --- Microorganisms --- Health Workforce
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Suspected vascular, peripheral nerve, and root nerve injuries present a particular challenge to any physician diagnosing and treating athletes. Injuries can range from "stingers" to effort vein thrombosis, and yet despite the common occurrence and potential severity of these and other conditions, little attention is paid to nerve and vascular injuries in sports medicine literature. This book is the first to gather experts in the field to fully address the complexity of neurovascular sports injuries. Nerve and Vascular Injuries in Sports Medicine takes a comprehensive look at anatomy, pathophysiology, examination and diagnosis of neurovascular sports injury, upper limb neurovascular syndrome, radicular and bracial plexus injury, and the lower extremity, including peripheral nerve injury. Illustrated throughout and dedicated to presenting the essential for managing nerve and vascular injuries, this book is an ideal resource for sports medicine physicians, athletic trainers, physical therapists, and all physicians who treat active patients.
Blood-vessels --Wounds and injuries --Diagnosis. --- Blood-vessels --Wounds and injuries --Treatment. --- Blood-vessels --Wounds and injuries. --- Emergency medicine. --- Family medicine. --- Medicine. --- Nervous system --Wounds and injuries --Diagnosis. --- Nervous system --Wounds and injuries --Treatment. --- Nervous system --- Blood-vessels --- Sports injuries --- Diagnosis --- Upper Extremity --- Peripheral Nerves --- Lower Extremity --- Trauma, Nervous System --- Extremities --- Sports Medicine --- Methods --- Athletes --- Blood Vessels --- Athletic Injuries --- Vascular Diseases --- Investigative Techniques --- Wounds and Injuries --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Persons --- Cardiovascular Diseases --- Nervous System Diseases --- Cardiovascular System --- Body Regions --- Medicine --- Peripheral Nervous System --- Named Groups --- Anatomy --- Diseases --- Nervous System --- Health Occupations --- Disciplines and Occupations --- Surgery - General and By Type --- Surgery & Anesthesiology --- Health & Biological Sciences --- Wounds and injuries --- Treatment --- Sports injuries. --- Sports medicine. --- Wounds and injuries. --- Athletic medicine --- Athletics --- Medicine and sports --- Physical education and training --- Sports --- Athletic injuries --- Sporting injuries --- Nerves --- Neurotrauma --- Neurotraumatology --- Angiology --- Vascular system --- Vasculature --- Medical aspects --- Accidents and injuries --- General practice (Medicine). --- Orthopedics. --- Primary care (Medicine). --- Physiotherapy. --- Medicine & Public Health. --- Sports Medicine. --- Primary Care Medicine. --- General Practice / Family Medicine. --- Sports sciences --- Sports medicine --- Cardiovascular system --- Family practice (Medicine) --- General practice (Medicine) --- Physicians (General practice) --- Medicine, Emergency --- Critical care medicine --- Disaster medicine --- Medical emergencies --- Orthopaedics --- Orthopedia --- Surgery --- Primary medical care --- Medical care
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Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.
Animal models in research. --- Nervous system -- Diseases -- Animal models. --- Nervous system -- Wounds and injuries -- Animal models. --- Nervous system -- Wounds and injuries. --- Nervous system --- Brain Diseases --- Trauma, Nervous System --- Back Injuries --- Investigative Techniques --- Wounds and Injuries --- Models, Animal --- Spinal Injuries --- Brain Injuries --- Craniocerebral Trauma --- Diseases --- Nervous System Diseases --- Central Nervous System Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Surgery & Anesthesiology --- Medicine --- Surgery - General and By Type --- Neurology --- Health & Biological Sciences --- Animal models --- Wounds and injuries --- Animal models. --- Medicine. --- Neurosciences. --- Neurology. --- Biomedicine. --- Animal Models. --- Animal experimentation --- Biological models --- Laboratory animals --- Research --- Organs (Anatomy) --- Neurosciences --- Laboratory animals. --- Animals, Experimental --- Animals, Laboratory --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Traumatisme --- Neurologia --- Models animals en la investigació --- Animals de laboratori --- Experimentació animal --- Investigació --- Models biològics --- Medicina --- Electrofisiologia --- Inhibició --- Neurocirurgia --- Neurooftalmologia --- Neuroimmunologia --- Neurologia pediàtrica --- Neurologia geriàtrica --- Neurologia veterinària --- Psicofisiologia --- Psicopatologia --- Urgències en neurologia --- Neuròlegs --- Lesions --- Traumatismes --- Accidents --- Cirurgia operatòria --- Etiologia --- Neurosi traumàtica --- Traumatismes dentals --- Ferides i lesions --- Xoc
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Edited by Sigrid Veasey, M.D. Center for Sleep and Respiratory Neurobiology Department of Medicine University of Pennsylvania Oxidative changes are observed in healthy aging of the nervous system, neurodegenerative processes and other forms of neural injury. At the same time, reactive oxygen species and reactive nitrogen species play critical roles in rapid response signaling, in learning, plasticity and in neuronal homeostasis. How do reactive oxygen and nitrogen molecules play such divergent roles in physiology and pathophysiology? How do these molecules contribute to neural injury, dysfunction and loss? The text Oxidative Neural Injury brings together international experts to systematically describe the biochemistry of reactive oxygen and nitrogen species signaling and then integrate this biochemistry into the neurobiology of redox in learning and plasticity and in healthy aging. This information will serve as the much-needed infrastructure for understanding in a more comprehensive manner how redox modifications contribute to neurodegenerative processes, in both early and late injury. Indeed, it is apparent that the development of effective therapies for neurodegenerative processes will first require a careful understanding of these critical roles of reactive oxygen and nitrogen molecules in neuronal signaling and cellular homeostasis, and this must be complemented with a comprehensive understanding of how reactive oxygen and nitrogen species perturb specific organelle and cellular functions.
Nervous system --Degeneration. --- Nervous system --Wounds and injuries. --- Oxidative stress. --- Nervous system --- Oxidative stress --- Oxidation-Reduction --- Oxidative Stress --- Physiology --- Reactive Oxygen Species --- Aging --- Neurodegenerative Diseases --- Reactive Nitrogen Species --- Biological Science Disciplines --- Growth and Development --- Oxygen Compounds --- Energy Metabolism --- Metabolism --- Nitroso Compounds --- Physicochemical Processes --- Free Radicals --- Nervous System Diseases --- Stress, Physiological --- Nitrogen Compounds --- Chemical Processes --- Diseases --- Physiological Processes --- Natural Science Disciplines --- Inorganic Chemicals --- Organic Chemicals --- Physicochemical Phenomena --- Metabolic Phenomena --- Chemical Phenomena --- Chemicals and Drugs --- Physiological Phenomena --- Phenomena and Processes --- Disciplines and Occupations --- Neurology --- Medicine --- Health & Biological Sciences --- Degeneration --- Wounds and injuries --- Degeneration. --- Degeneration, Nerve --- Nerve degeneration --- Nervous system degeneration --- Neurodegenerative disease --- Neurodegenerative diseases --- Neurodegenerative disorders --- Neuron degeneration --- Nissl degeneration --- Retrograde degeneration --- Wallerian degeneration --- Degeneration and regeneration --- Medicine. --- Human physiology. --- Neurosciences. --- Neurology. --- Biochemistry. --- Neurobiology. --- Medicine & Public Health. --- Biochemistry, general. --- Human Physiology. --- Oxidation-reduction reaction --- Stress (Physiology) --- Degeneration (Pathology) --- Human biology --- Medical sciences --- Human body --- Neurosciences --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Neural sciences --- Neurological sciences --- Neuroscience --- Neuropsychiatry --- Composition --- Neurology .
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