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The book will take a systematic look at nanoparticle risks within the paradigm of risk assessment, consider the limitations of this paradigm in dealing with the extreme uncertainties regarding many aspects of nanoparticle exposure and toxicity, and suggest new methods for assessing and managing risks in this context. It will consider the occupational environment where the potential for human exposure is the greatest as well as the issues relevant to occupational exposure assessment (e.g., the exposure metric) and the evidence from toxicological and epidemiological studies. A chapter will b
Biocompatible Materials. --- Biotechnlogy. --- Biotechnology. --- Nanoparticles - Environmental aspects. --- Nanoparticles -- Health aspects. --- Nanoparticles - Risk assessment. --- Nanostructured materials -- Biocompatibility. --- Nanostructures. --- Nanotechnology. --- Nanoparticles --- Environmental Pollution --- Epidemiologic Measurements --- Risk --- Nanostructures --- Risk Management --- Probability --- Public Health --- Organization and Administration --- Manufactured Materials --- Statistics as Topic --- Environment and Public Health --- Health Services Administration --- Technology, Industry, and Agriculture --- Epidemiologic Methods --- Health Care --- Technology, Industry, Agriculture --- Health Care Evaluation Mechanisms --- Investigative Techniques --- Quality of Health Care --- Health Care Quality, Access, and Evaluation --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Risk Assessment --- Environmental Exposure --- Civil & Environmental Engineering --- Health & Biological Sciences --- Chemical & Materials Engineering --- Engineering & Applied Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Environmental Engineering --- Materials Science --- Risk assessment --- Environmental aspects --- Nanoparticles. --- Environmental aspects. --- Nano-particles --- NPs (Nanoparticles) --- Nanostructured materials --- Particles --- Nanoscale particles --- Health aspects. --- Risk assessment.
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"Environmental safety and health has become an existential issue for the nanotechnology movement, and the international community is responding to this challenge with major multi-disciplinary research efforts. This compilation covers both the toxicology and biomedical applications of nanomaterials in a form that will be a useful reference and starting point for people working in or entering this rapidly growing field." --Dr. Robert Hurt, Director, The Institute for Molecular and Nanoscale Innovation (IMaNI) at Brown University, Professor, Brown University, Providence, RI 02917 USA In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first detailed overviews of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.
Biomedical engineering -- Safety measures. --- Biomedical engineering. --- Nanoparticles -- Environmental aspects. --- Nanoparticles -- Health aspects. --- Nanoparticles -- Toxicity. --- Nanoparticles -- Toxicology. --- Nanostructured materials. --- Safety. --- Nanoparticles --- Biomedical engineering --- Nanostructured materials --- Nanomedicine --- Safety --- Toxicity Tests --- Biomedical Technology --- Investigative Techniques --- Nanostructures --- Accident Prevention --- Nanotechnology --- Technology --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Manufactured Materials --- Miniaturization --- Accidents --- Natural Science Disciplines --- Public Health --- Disciplines and Occupations --- Technology, Industry, and Agriculture --- Technology, Industry, Agriculture --- Environment and Public Health --- Health Care --- Biomedical Engineering --- Pharmacy, Therapeutics, & Pharmacology --- Health & Biological Sciences --- Health aspects --- Toxicology --- Safety measures --- Environmental aspects --- Safety measures. --- Nanomaterials --- Nanometer materials --- Nanophase materials --- Nanostructure controlled materials --- Nanostructure materials --- Ultra-fine microstructure materials --- Clinical engineering --- Medical engineering --- Materials science. --- Immunology. --- Biophysics. --- Biological physics. --- Nanotechnology. --- Materials Science. --- Biomedical Engineering. --- Characterization and Evaluation of Materials. --- Biophysics and Biological Physics. --- Microstructure --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Surfaces (Physics). --- Biomedical Engineering and Bioengineering. --- Biological and Medical Physics, Biophysics. --- Immunobiology --- Life sciences --- Serology --- Physics --- Surface chemistry --- Surfaces (Technology) --- Molecular technology --- Nanoscale technology --- High technology --- Biological physics --- Biology --- Medical sciences --- Material science --- Physical sciences
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A huge effort is put into the science of nanoparticles and their production. In many cases it is unavoidable that nanoparticles are released into the environment, either during the production processes or during the use of a product made from these particles. It is also realized that combustion processes like traffic and power plants release nanoparticles into the atmosphere. However it is not known how nanoparticles interact with the human body, especially upon inhalation. At the same time research activities are devoted to understand how nano-sized medicine particles can be used to administer medicines via inhalation. In any case it is absolutely necessary to know how the nanoparticles interfere with the inhalation system, how they deposit and affect on the human system. Three main themes are discussed: Nanoparticle sources and production Nanoparticle inhalation and deposition Toxicological and medical consequences of nanoparticles Each theme is covered comprehensively, starting at nano-quantum effects up to technical and medical applications such as measuring equipment and inhalation instrumentation. This book brings together all sub-disciplines in the field related to aerosol nanoparticles. Each chapter is written by a world expert, giving the state of the art information and challenging open questions. The last chapter summarizes in an interdisciplinary way what is already known and what still is ahead of us. .
Nanoparticles --Environmental aspects. --- Nanoparticles --Health aspects. --- Nanoparticles --Toxicology. --- Nanoparticles --- Nanotechnology --- Biomedical Technology --- Environmental Exposure --- Nanostructures --- Environmental Pollutants --- Drug Therapy --- Investigative Techniques --- Drug Delivery Systems --- Nanomedicine --- Inhalation Exposure --- Methods --- Air Pollutants --- Therapeutics --- Environmental Pollution --- Miniaturization --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Manufactured Materials --- Technology --- Natural Science Disciplines --- Toxic Actions --- Technology, Industry, and Agriculture --- Chemical Actions and Uses --- Public Health --- Disciplines and Occupations --- Environment and Public Health --- Technology, Industry, Agriculture --- Chemicals and Drugs --- Health Care --- Civil & Environmental Engineering --- Health & Biological Sciences --- Biomedical Engineering --- Environmental Engineering --- Engineering & Applied Sciences --- Toxicology --- Health aspects --- Environmental aspects --- Toxicology. --- Health aspects. --- Environmental aspects. --- Medicine. --- Pharmacology. --- Public health. --- Nanotechnology. --- Environmental health. --- Biomedicine. --- Biomedicine general. --- Nanotechnology and Microengineering. --- Public Health. --- Environmental Health. --- Pharmacology/Toxicology. --- Nanostructured materials --- Particles --- Engineering. --- Environmental Medicine. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Construction --- Industrial arts --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Biomedicine, general. --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Environmental quality --- Health --- Health ecology --- Public health --- Environmental engineering --- Health risk assessment --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Molecular technology --- Nanoscale technology --- High technology --- Physiological effect
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