Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Neuropeptide Y (NPY) is a ubiquitous and important messenger in the nervous system, with a wide range of physiological roles. It is involved in the body energy balance and is one of the most potent stimuli of food intake known. NPY also acts to regulate central and peripheral autonomic functions.This book, written by academic and industrial experts in the field, links the most recent basic experimental knowledge about NPY and its receptors with areas of clinical importance.This book will be of interest to those working in all areas of research affected by NPY, such as food intak

Neuropeptide Y. --- Neuropeptides. --- Brain peptides --- Nerve tissue proteins --- Neurotransmitters --- Peptides --- Neuropeptide tyrosine --- NPY (Neuropeptide) --- Neuropeptides

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via multiple receptors, Y1-Y5, which are widespread not only in neurons but also in a variety of non-neural and immune cells. These peptides have been known as important regulators of many essential systems, such as blood pressure and cardiac function, food consumption and energy homeostasis. However, in recent years, they have also become recognized for their role as potent modulators of cell growth and immune functions with broad implications in chronic inflammatory diseases, cancer and angiogenesis. In this book, experts in the field analyze recent evidence supporting the role of NPY family of peptides in regulation of the immune/inflammatory system with special reference to its medical and therapeutic implications.

Neuropeptide Y --- Neuropeptides. --- Pathophysiology. --- Brain peptides --- Nerve tissue proteins --- Neurotransmitters --- Peptides --- Neuropeptide tyrosine --- NPY (Neuropeptide) --- Neuropeptides --- Immunology. --- Cytology. --- Neurobiology. --- Oncology. --- Cell Biology. --- Cancer Research. --- Tumors --- Neurosciences --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Immunobiology --- Life sciences --- Serology --- Cell biology. --- Cancer research. --- Cancer research

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders. The identification of multiple receptors for the members of the NPY and PYY family of peptides provides new opportunities for discovery of specific NPY antagonists and agonists that have vast clinical potential. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists, which are in clinical development for obesity. NPY Y1 receptor antagonists are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders is also actively pursued. The chapters in this book are written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine. The ideal complement to this volume is the book NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis, and Cancer, recently published by the same editors in the Birkhäuser book series Progress in Inflammation Research. Both volumes together give a comprehensive overview of the NPY family of peptides. .

Neuropeptide Y - Pathophysiology. --- Neuropeptide Y --- Gastrointestinal hormones --- Neuropeptides --- Peptides --- Nerve Tissue Proteins --- Amino Acids, Peptides, and Proteins --- Proteins --- Chemicals and Drugs --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Pathophysiology --- Derivatives --- Pathophysiology. --- Endocrinological gastroenterology --- Gut hormones --- Regulatory gut peptides --- RGP (Hormones) --- Neuropeptide tyrosine --- NPY (Neuropeptide) --- Medicine. --- Biomedicine. --- Biomedicine general. --- Hormones --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Biomedicine, general. --- Medicine --- Biology --- Biomedical Research. --- Research. --- Biological research --- Biomedical research