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Excitatory amino acids : clinical results with antagonists
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ISBN: 9780125468206 0125468202 9780080531342 0080531342 9786611033484 1281033480 Year: 1997 Publisher: San Diego, Calif. : Academic Press,

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Abstract

Glutamate is the major excitatory neurotransmitter in the brain and dysfunction of glutamate transmission is the likely cause of a variety of diseases including neurodegeneration following cerebral ischemia, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, spasticity, emesis, chronic pain, and schizophrenia. Excitatory amino acid receptor agonists and antagonists are therefore of major interest as potential drugs for central nervous system disorders. Excitatory Amino Acids is the first book entirely dedicated to the results of human testing of modulators of excitatory amino

Biology of the NMDA receptor
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ISBN: 1420044141 9786611863135 1281863130 142004415X 0429144849 Year: 2008 Publisher: Boca Raton, Fla. : Taylor & Francis,

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Abstract

The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world's leading authorities on NMDA receptors, ""Biology of the NMDA Receptor"" brings together virtually all the players in this important field.

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