Abstract | Keywords | Export | Availability | Bookmark

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Muscle disease represents an important health threat to the general population. For thousands of years, a cure has been deemed extremely remote, if not impossible, for many relentless muscle diseases such as Duchenne muscular dystrophy. The cloning of muscle disease genes and the prospect of introducing the normal gene to diseased muscle by gene therapy finally bring the hope of a cure. Tremendous progress has been made chasing the muscle gene therapy dream over the past two decades. Valuable information is scattered in the literature. This book represents the first compilation specifically dedicated to issues related to muscle gene therapy. It offers a much needed, up-to-date overview and perspective on the current strategies and status of muscle gene therapy. It covers the cutting edge development of a variety of fascinating strategies such as exon-skipping, AAV gene therapy, RNAi and stem cell approaches. With contributions from prominent investigators in the field, it provides a framework to translate bench science to clinical practice in the upcoming years. This book is a must-have for anyone who is interested in muscle gene therapy including established investigators, clinicians, post-doctoral fellows, graduate students, funding agencies, patients and their families and friends.

Muscles -- Disease. --- Muscles -- Diseases -- Gene therapy -- Laboratory manuals. --- Muscles -- Diseases -- Gene therapy. --- Muscles --- Biological Therapy --- Muscular Dystrophies --- Genetic Engineering --- Investigative Techniques --- Biology --- Genetic Diseases, X-Linked --- Muscular Disorders, Atrophic --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Genetic Diseases, Inborn --- Biological Science Disciplines --- Genetic Techniques --- Therapeutics --- Muscular Dystrophy, Duchenne --- Gene Therapy --- Methods --- Genetics --- Natural Science Disciplines --- Congenital, Hereditary, and Neonatal Diseases and Abnormalities --- Muscular Diseases --- Diseases --- Disciplines and Occupations --- Musculoskeletal Diseases --- Neuromuscular Diseases --- Nervous System Diseases --- Medicine --- Health & Biological Sciences --- Pathology --- Musculoskeletal System Diseases --- Gene therapy --- Gene therapy. --- Diseases. --- Myopathy --- Therapy, Gene --- Medicine. --- Human genetics. --- Immunology. --- Virology. --- Developmental biology. --- Biomedicine. --- Human Genetics. --- Developmental Biology. --- Genetic engineering --- Medical virology. --- Medical microbiology --- Virology --- Virus diseases --- Immunobiology --- Life sciences --- Serology --- Development (Biology) --- Growth --- Ontogeny --- Heredity, Human --- Human biology --- Physical anthropology --- Microbiology