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Pathology, Molecular. --- Molecular pathology --- Molecular biology --- Physiology, Pathological

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The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care. This text focuses on clinical utility and validity and serves as an “owner’s manual” in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.

Pathology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Pathology, Molecular. --- Molecular pathology --- Molecular biology --- Physiology, Pathological --- Medical genetics. --- Diagnostic Molecular Pathology --- Molecular Diagnostics --- Diagnostic Molecular Pathologies --- Diagnostic, Molecular --- Diagnostics, Molecular --- Molecular Diagnostic --- Molecular Pathologies --- Molecular Pathologies, Diagnostic --- Molecular Pathology --- Molecular Pathology, Diagnostic --- Pathologies, Diagnostic Molecular --- Pathologies, Molecular --- Pathology, Diagnostic Molecular --- Clinical genetics --- Heredity of disease --- Human genetics --- Pathology --- Genetic disorders --- Genetic aspects

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Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare.

Molecular diagnosis. --- Cells --- Pathology, Molecular. --- Diagnostic use. --- Molecular pathology --- Molecular biology --- Physiology, Pathological --- Organisms --- Cytology --- Diagnosis --- Molecular diagnostics --- Molecular aspects

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Pathology, Molecular --- Pathology, Experimental --- Pathology --- Pathologie moléculaire --- Pathologie expérimentale --- Pathology, Experimental. --- Pathology, Molecular. --- Molecular pathology --- Experimental pathology --- Molecular biology --- Physiology, Pathological --- moleculaire biologie

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Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer.This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step

Pathology, Molecular. --- Prostate --- Rectum --- Immunochemistry. --- In situ hybridization. --- Cancer. --- Diseases. --- Nucleic acid hybridization --- Biochemistry --- Immunity --- Proctology --- Molecular pathology --- Molecular biology --- Physiology, Pathological