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Molecular Medicine. --- Bioengineering. --- Bio engineering --- Biological Engineering --- Bio-Engineering --- Bio engineerings --- Bioengineerings --- Engineering, Biological --- engineering, Bio --- engineerings, Bio --- Medicine, Molecular --- Medicines, Molecular --- Molecular Medicines --- Genetics, Medical
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Molecular biology. --- Human physiology. --- Molecular medicine and medicinal chemistry. --- Human biology --- Medical sciences --- Physiology --- Human body --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Molecular Medicine. --- Medicine, Molecular --- Medicines, Molecular --- Molecular Medicines --- Genetics, Medical
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Molecular genetics. --- Genetic Phenomena --- Genetic Techniques. --- Genomics. --- Biological Evolution. --- Molecular Medicine. --- genetics. --- Medicine, Molecular --- Medicines, Molecular --- Molecular Medicines --- Genetics, Medical --- Evolution, Biological --- Sociobiology --- Comparative Genomics --- Comparative Genomic --- Genomic, Comparative --- Genomics, Comparative --- Human Genome Project --- Genome --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Genetics --- Genetic Counseling --- Molecular biology --- methods
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biomedicine --- genetics --- bioinformatics --- molecular biology --- gene editing --- Molecular biotechnology --- Biomedical engineering --- Biotechnology. --- Biomedical Engineering. --- Molecular biotechnology. --- Biomedical engineering. --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Biotechnology --- Engineering, Biomedical --- Clinical Engineering --- Engineering, Clinical --- Biomedical Technology --- Biotechnologies --- Molecular Medicine --- Biomedical Engineering --- Medicine, Molecular --- Medicines, Molecular --- Molecular Medicines --- Genetics, Medical
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Clinical biochemistry --- Molecular biology --- Molecular Medicine. --- Molecular Biology. --- Clinical biochemistry. --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Medicine, Molecular --- Medicines, Molecular --- Molecular Medicines --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemical Genetics --- Biology, Molecular --- Genetics, Biochemical --- Genetics, Molecular --- Molecular Genetics --- Biochemical Genetic --- Genetic, Biochemical --- Genetic, Molecular --- Molecular Genetic --- Biochemistry. --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Pathology --- Genetic Phenomena --- Biochimie --- Biologie moléculaire --- Biologie moléculaire --- Molecular Biology --- Pathology, Molecular --- Biochimie clinique --- Pathologie moléculaire --- Biochimie. --- biochemistry. --- Pathology, Molecular. --- Molecular pathology --- Physiology, Pathological --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Composition
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This book focuses on the biological mechanisms of minimal residual disease (MRD) and recurrence. It integrates this biology in solid cancers and in hematological malignancies. It reports also on technological advancements for monitoring MRD, derived from mechanistic insights. Chapters in solid and hematological malignancies address stem cell biology, genetics, epigenetics and micro-environmental regulation of dormant MRD. Novel insight into technologies for molecular phenotyping of MRD and monitoring of CTCs, DTCs and cell free RNA and DNA are also addressed extensively. Five chapters explore the above concepts in solid cancers such as prostate, breast, melanoma, head and neck and esophageal. Two chapters also explore the basic mechanisms of vascular biology targeting and epigenetic mechanisms regulating pluripotency programs during dormancy. Similar biology is explored in hematological malignancies such as T-ALL, CML, AML and multiple myeloma in additional four chapters. This book is edited and prefaced by Dr. Julio Aguirre-Ghiso, an expert in dormancy and recurrence. The chapters are written by world-recognized experts Drs. Ravi Bahtia, Samir Parekh, Russel Taichman, Monica Guzman, David Hoon, Denis Schewe, Irmela Jeremias, Cyrus Ghajar, Maria Soledad Sosa and Nicholas Stoecklein. The topic of this book is of particular interest to both basic cancer cell biologists and physician scientists that are working to provide a more integrated view of the biology of MRD and to those interested in working on or learning about this paradigm. The integrated and cross-disciplinary focus of the book from biology to medicine seeks to help bridge gaps to improve cancer care and prevent recurrences.
Cancer --- Neoplasm, Residual. --- Molecular aspects. --- Oncology. --- Human genetics. --- Medicine. --- Cytology. --- Drug interactions. --- Cancer Research. --- Human Genetics. --- Molecular Medicine. --- Cell Biology. --- Drug Resistance. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Genetics --- Heredity, Human --- Physical anthropology --- Tumors --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Interactions, Drug --- Drugs --- Side effects --- Health Workforce --- Cancer research. --- Molecular biology. --- Cell biology. --- Drug resistance. --- Resistance to drugs --- Pharmacology --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cancer research --- Drug Resistance, Neoplasm. --- Antineoplastic Agent Resistance --- Neoplasm Drug Resistance --- Resistance, Antineoplastic Agent --- Resistance, Antineoplastic Drug --- Antibiotic Resistance, Neoplasm --- Antineoplastic Drug Resistance --- Drug Resistance, Antineoplastic --- Cellular Biology --- Cytology --- Biologies, Cell --- Biologies, Cellular --- Biology, Cell --- Biology, Cellular --- Cell Biologies --- Cellular Biologies --- Medicine, Molecular --- Medicines, Molecular --- Molecular Medicines --- Genetics, Medical --- Genetics, Human
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