Listing 1 - 6 of 6 |
Sort by
|
Choose an application
In recent years, an increasing number of manuscripts have been published addressing the deleterious role of arginase in endothelial dysfunction. ROS have been shown to play a crucial role in arginase activation, which in turn leads to eNOS dysfunction.
Immunologic diseases. --- eNOS --- Reactive Oxygen Species --- L-citrulline --- arginase inhibitors --- vessel wall remodeling --- impaired vasorelaxation --- microvascular permeability
Choose an application
The vascular endothelium lining the inner surface of blood vessels serves as the first interface for circulating blood components to interact with cells of the vascular wall and surrounding extravascular tissues. In addition to regulating blood delivery and perfusion, a major function of vascular endothelia, especially those in exchange microvessels (capillaries and postcapillary venules), is to provide a semipermeable barrier that controls blood-tissue exchange of fluids, nutrients, and metabolic wastes while preventing pathogens or harmful materials in the circulation from entering into tissues. During host defense against infection or tissue injury, endothelial barrier dysfunction occurs as a consequence as well as cause of inflammatory responses. Plasma leakage disturbs fluid homeostasis and impairs tissue oxygenation, a pathophysiological process contributing to multiple organ dysfunction associated with trauma, infection, metabolic disorder, and other forms of disease. In this book, we provide an updated overview of microvascular endothelial barrier structure and function in health and disease. The discussion is initiated with the basic physiological principles of fluid and solute transport across microvascular endothelium, followed by detailed information on endothelial cell-cell and cell-matrix interactions and the experimental techniques that are employed to measure endothelial permeability. Further discussion focuses on the signaling and molecular mechanisms of endothelial barrier responses to various stimulations or drugs, as well as their relevance to several common clinical conditions. Taken together, this book provides a comprehensive analysis of microvascular endothelial cell and molecular pathophysiology. Such information will assist scientists and clinicians in advanced basic and clinical research for improved health care.
Vascular endothelium. --- Blood Vessels --- Endothelium --- Epithelium --- Cardiovascular System --- Anatomy --- Tissues --- Endothelium, Vascular --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Capillaries --- Endothelium, Vascular. --- Capillary Permeability. --- Permeability. --- Microvascular permeability --- Endothelial barrier --- Cell-cell junction --- Cell-matrix adhesion --- Cytoskeleton --- Signal transduction
Choose an application
Blood physiology. Circulatory physiology --- CAPILLARY PERMEABILITY --- Capillary Permeability. --- Microvascular Permeability --- Permeability, Capillary --- Permeability, Microvascular --- Vascular Permeability --- Capillary Permeabilities --- Microvascular Permeabilities --- Permeabilities, Capillary --- Permeabilities, Microvascular --- Permeabilities, Vascular --- Permeability, Vascular --- Vascular Permeabilities --- Blood-Brain Barrier --- Blood-Retinal Barrier --- Blood-Testis Barrier --- Blood-Air Barrier --- Blood-Aqueous Barrier --- Blood-Nerve Barrier --- Transendothelial and Transepithelial Migration --- Capillary Permeability
Choose an application
This book collects 17 original research papers and 9 reviews that are part of the Special Issue “Cellular Oxidative Stress”, published in the journal Antioxidants. Oxidative stress on a cellular level affects the function of tissues and organs and may eventually lead to disease. Therefore, a precise understanding of how oxidative stress develops and can be counteracted is of utmost importance. The scope of the book is to emphasize the latest findings on the cellular targets of oxidative stress and the potential beneficial effect of antioxidants on human health.
Medicine --- neuroinflammation --- clinical --- palmitoylethanolamide --- luteolin --- co-ultramicronization --- CNS pathology --- adaptive immune response --- cell homeostasis --- legumes --- liver --- hepatic steatosis --- lipid dyshomeostasis --- ROS --- traumatic brain injury --- palmitoylethanolamide (PEA) --- therapeutic strategies --- oxidative stress. --- RNA-Seq --- RPE --- Retinitis pigmentosa --- A2E --- diabetes --- glucose exposure --- oxidative stress --- Band 3 protein --- erythrocytes --- SO42− --- 4-hydroxy-2-nonenal --- 3-glutathionyl-4-hydroxynonanal --- astrocytoma cells --- soy --- soybeans --- soy foods --- antioxidants --- reactive oxygen species --- cardiovascular diseases --- cancer --- paw edema --- cashew nuts --- antioxidant --- inflammation --- polyphenols --- analgesic --- d-Galactose --- glycation --- SO42− uptake --- anion exchange --- diseases --- immune system --- NF-κB --- cigarette smoke extract --- nasal fibroblasts --- tissue inhibitor of metalloproteinases --- matrix metalloproteinase --- steroids --- Plasmodium falciparum --- syk kinase inhibitors --- artemisinin derivatives --- hemichromes --- cellular redox state --- mitochondrial function --- cisplatin nephrotoxicity --- acute pancreatitis --- obesity --- nitrosative stress --- PGC-1α --- microparticles --- vesiculation --- band 3 --- tert-Bytyl hydroperoxide t-BOOH --- nitric oxide donor --- calcium ionophore A23187 --- age-related macular degeneration (AMD) --- diet --- Substance-P --- adipose-derived stem cells --- paracrine factors --- epilepsy --- status epilepticus --- Trolox --- HeLa --- prooxidant --- AVD --- apoptosis --- neurodegeneration --- ncRNA --- miRNA --- tRNA fragments --- lncRNA --- circRNA --- preeclampsia --- hemostasis --- platelets --- coagulation --- fish --- mucosal immunity --- nasal immunity --- peroxide --- vitamin C --- NAC --- immunosenescence --- T cells --- vaccination --- aging --- microvascular permeability --- bradykinin --- interleukin 1β --- NADPH oxidase --- simvastatin --- molecular hydrogen --- autophagy --- matrix metalloproteinases --- reactive oxygen species (ROS) --- phytochemicals --- dietary chemicals --- natural compounds --- programmed cell death --- anoikis --- ferroptosis --- pyroptosis --- neuroinflammation --- clinical --- palmitoylethanolamide --- luteolin --- co-ultramicronization --- CNS pathology --- adaptive immune response --- cell homeostasis --- legumes --- liver --- hepatic steatosis --- lipid dyshomeostasis --- ROS --- traumatic brain injury --- palmitoylethanolamide (PEA) --- therapeutic strategies --- oxidative stress. --- RNA-Seq --- RPE --- Retinitis pigmentosa --- A2E --- diabetes --- glucose exposure --- oxidative stress --- Band 3 protein --- erythrocytes --- SO42− --- 4-hydroxy-2-nonenal --- 3-glutathionyl-4-hydroxynonanal --- astrocytoma cells --- soy --- soybeans --- soy foods --- antioxidants --- reactive oxygen species --- cardiovascular diseases --- cancer --- paw edema --- cashew nuts --- antioxidant --- inflammation --- polyphenols --- analgesic --- d-Galactose --- glycation --- SO42− uptake --- anion exchange --- diseases --- immune system --- NF-κB --- cigarette smoke extract --- nasal fibroblasts --- tissue inhibitor of metalloproteinases --- matrix metalloproteinase --- steroids --- Plasmodium falciparum --- syk kinase inhibitors --- artemisinin derivatives --- hemichromes --- cellular redox state --- mitochondrial function --- cisplatin nephrotoxicity --- acute pancreatitis --- obesity --- nitrosative stress --- PGC-1α --- microparticles --- vesiculation --- band 3 --- tert-Bytyl hydroperoxide t-BOOH --- nitric oxide donor --- calcium ionophore A23187 --- age-related macular degeneration (AMD) --- diet --- Substance-P --- adipose-derived stem cells --- paracrine factors --- epilepsy --- status epilepticus --- Trolox --- HeLa --- prooxidant --- AVD --- apoptosis --- neurodegeneration --- ncRNA --- miRNA --- tRNA fragments --- lncRNA --- circRNA --- preeclampsia --- hemostasis --- platelets --- coagulation --- fish --- mucosal immunity --- nasal immunity --- peroxide --- vitamin C --- NAC --- immunosenescence --- T cells --- vaccination --- aging --- microvascular permeability --- bradykinin --- interleukin 1β --- NADPH oxidase --- simvastatin --- molecular hydrogen --- autophagy --- matrix metalloproteinases --- reactive oxygen species (ROS) --- phytochemicals --- dietary chemicals --- natural compounds --- programmed cell death --- anoikis --- ferroptosis --- pyroptosis
Choose an application
This book collects 17 original research papers and 9 reviews that are part of the Special Issue “Cellular Oxidative Stress”, published in the journal Antioxidants. Oxidative stress on a cellular level affects the function of tissues and organs and may eventually lead to disease. Therefore, a precise understanding of how oxidative stress develops and can be counteracted is of utmost importance. The scope of the book is to emphasize the latest findings on the cellular targets of oxidative stress and the potential beneficial effect of antioxidants on human health.
Medicine --- neuroinflammation --- clinical --- palmitoylethanolamide --- luteolin --- co-ultramicronization --- CNS pathology --- adaptive immune response --- cell homeostasis --- legumes --- liver --- hepatic steatosis --- lipid dyshomeostasis --- ROS --- traumatic brain injury --- palmitoylethanolamide (PEA) --- therapeutic strategies --- oxidative stress. --- RNA-Seq --- RPE --- Retinitis pigmentosa --- A2E --- diabetes --- glucose exposure --- oxidative stress --- Band 3 protein --- erythrocytes --- SO42− --- 4-hydroxy-2-nonenal --- 3-glutathionyl-4-hydroxynonanal --- astrocytoma cells --- soy --- soybeans --- soy foods --- antioxidants --- reactive oxygen species --- cardiovascular diseases --- cancer --- paw edema --- cashew nuts --- antioxidant --- inflammation --- polyphenols --- analgesic --- d-Galactose --- glycation --- SO42− uptake --- anion exchange --- diseases --- immune system --- NF-κB --- cigarette smoke extract --- nasal fibroblasts --- tissue inhibitor of metalloproteinases --- matrix metalloproteinase --- steroids --- Plasmodium falciparum --- syk kinase inhibitors --- artemisinin derivatives --- hemichromes --- cellular redox state --- mitochondrial function --- cisplatin nephrotoxicity --- acute pancreatitis --- obesity --- nitrosative stress --- PGC-1α --- microparticles --- vesiculation --- band 3 --- tert-Bytyl hydroperoxide t-BOOH --- nitric oxide donor --- calcium ionophore A23187 --- age-related macular degeneration (AMD) --- diet --- Substance-P --- adipose-derived stem cells --- paracrine factors --- epilepsy --- status epilepticus --- Trolox --- HeLa --- prooxidant --- AVD --- apoptosis --- neurodegeneration --- ncRNA --- miRNA --- tRNA fragments --- lncRNA --- circRNA --- preeclampsia --- hemostasis --- platelets --- coagulation --- fish --- mucosal immunity --- nasal immunity --- peroxide --- vitamin C --- NAC --- immunosenescence --- T cells --- vaccination --- aging --- microvascular permeability --- bradykinin --- interleukin 1β --- NADPH oxidase --- simvastatin --- molecular hydrogen --- autophagy --- matrix metalloproteinases --- reactive oxygen species (ROS) --- phytochemicals --- dietary chemicals --- natural compounds --- programmed cell death --- anoikis --- ferroptosis --- pyroptosis --- n/a
Choose an application
This book collects 17 original research papers and 9 reviews that are part of the Special Issue “Cellular Oxidative Stress”, published in the journal Antioxidants. Oxidative stress on a cellular level affects the function of tissues and organs and may eventually lead to disease. Therefore, a precise understanding of how oxidative stress develops and can be counteracted is of utmost importance. The scope of the book is to emphasize the latest findings on the cellular targets of oxidative stress and the potential beneficial effect of antioxidants on human health.
neuroinflammation --- clinical --- palmitoylethanolamide --- luteolin --- co-ultramicronization --- CNS pathology --- adaptive immune response --- cell homeostasis --- legumes --- liver --- hepatic steatosis --- lipid dyshomeostasis --- ROS --- traumatic brain injury --- palmitoylethanolamide (PEA) --- therapeutic strategies --- oxidative stress. --- RNA-Seq --- RPE --- Retinitis pigmentosa --- A2E --- diabetes --- glucose exposure --- oxidative stress --- Band 3 protein --- erythrocytes --- SO42− --- 4-hydroxy-2-nonenal --- 3-glutathionyl-4-hydroxynonanal --- astrocytoma cells --- soy --- soybeans --- soy foods --- antioxidants --- reactive oxygen species --- cardiovascular diseases --- cancer --- paw edema --- cashew nuts --- antioxidant --- inflammation --- polyphenols --- analgesic --- d-Galactose --- glycation --- SO42− uptake --- anion exchange --- diseases --- immune system --- NF-κB --- cigarette smoke extract --- nasal fibroblasts --- tissue inhibitor of metalloproteinases --- matrix metalloproteinase --- steroids --- Plasmodium falciparum --- syk kinase inhibitors --- artemisinin derivatives --- hemichromes --- cellular redox state --- mitochondrial function --- cisplatin nephrotoxicity --- acute pancreatitis --- obesity --- nitrosative stress --- PGC-1α --- microparticles --- vesiculation --- band 3 --- tert-Bytyl hydroperoxide t-BOOH --- nitric oxide donor --- calcium ionophore A23187 --- age-related macular degeneration (AMD) --- diet --- Substance-P --- adipose-derived stem cells --- paracrine factors --- epilepsy --- status epilepticus --- Trolox --- HeLa --- prooxidant --- AVD --- apoptosis --- neurodegeneration --- ncRNA --- miRNA --- tRNA fragments --- lncRNA --- circRNA --- preeclampsia --- hemostasis --- platelets --- coagulation --- fish --- mucosal immunity --- nasal immunity --- peroxide --- vitamin C --- NAC --- immunosenescence --- T cells --- vaccination --- aging --- microvascular permeability --- bradykinin --- interleukin 1β --- NADPH oxidase --- simvastatin --- molecular hydrogen --- autophagy --- matrix metalloproteinases --- reactive oxygen species (ROS) --- phytochemicals --- dietary chemicals --- natural compounds --- programmed cell death --- anoikis --- ferroptosis --- pyroptosis --- n/a
Listing 1 - 6 of 6 |
Sort by
|